Compound
D0774 | ami-193
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 5.82±3.05 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 7.74 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 25.96±12.20 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(4-fluorophenoxy)propyl)-1-phenyl- | 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(4-fluorophenoxy)propyl]-1-phenyl- | 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(p-fluorophenoxy)propyl]-1-phenyl-; |
| 471LF4O004 | 510-74-7 | 8-(3-(4-Fluorophenoxy)propyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one |
| 8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]-decanone | 8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one | ACM510747 |
| AKOS024458544 | AMI-193 | API0006556 |
| B6335 | BDBM86525 | BN0070 |
| BPBio1_001087 | BPBio1_001259 | BRD-K94512704-001-02-1 |
| Biomol-NT_000039 | Biomol-NT_000087 | CAS-510-74-7 |
| CAS_77445 | CHEBI:64207 | CHEMBL79834 |
| CTK8F7702 | DSSTox_CID_22579 | DSSTox_GSID_42579 |
| DSSTox_RID_80051 | DTXSID6042579 | Espiramida |
| Espiramida [INN-Spanish] | FJUKDAZEABGEIH-UHFFFAOYSA-N | Fluroxyspiramine |
| GS-9308 | GTPL175 | L023992 |
| NCGC00024633-01 | NCGC00024633-02 | NCGC00024633-03 |
| NCGC00024633-04 | NCGC00024633-05 | NCGC00024633-06 |
| NCGC00024633-07 | NSC_77445 | Q7577785 |
| R 5808 | R-5808 | SCHEMBL2110721 |
| SR-01000597677 | SR-01000597677-1 | Spiramide |
| Spiramide [INN] | Spiramidum | Spiramidum [INN-Latin] |
| Tocris-0524 | Tox21_110914 | Tox21_110914_1 |
| UNII-471LF4O004 | ZINC1846593 |