D0642 | 2,4-bis(1-methyl-1-phenylethyl)phenol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 3.49±1.51 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 2.82 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 43.93±17.40 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Warning |
Aggregated GHS information provided by 41 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 1 of 41 companies. For more detailed information, please visit ECHA C&L website Of the 3 notification(s) provided by 40 of 41 companies with hazard statement code(s): H319 (97.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H413 (95%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P273, P280, P305+P351+P338, P337+P313, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | unreported | 3500mg/kg (3500mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 655, 1969. | |
| rat | LD50 | oral | 4100mg/kg (4100mg/kg) | SPI Bulletin. Vol. 1/75-19B, | |
| 106060-52-0 | 2,4-BIS(,-DIMETHYLBENZYL)PHENOL | 2,4-Bis(1-methyl-1-phenylethyl)phenol |
| 2,4-Bis(2-phenyl-2-propanyl)phenol | 2,4-Bis(alpha,alpha-dimethylbenzyl)phenol | 2,4-Bis(alpha,alpha-dimethylbenzyl)phenol, 95% |
| 2,4-Bis(dimethylbenzyl)phenol | 2,4-DICUMYL PHENOL | 2,4-Di(alpha-methylstyryl)phenol |
| 2,4-Di-(alpha, alpha-dimethylbenzyl)phenol | 2,4-Di-(alpha,alpha-dimethylbenzyl)phenol | 2,4-Di-alpha-cumylphenol |
| 2,4-Dicumylphenol | 2,4-bis(2-phenylpropan-2-yl)phenol | 2,4-di(alpha,alpha-dimethylbenzyl)phenol |
| 2772-45-4 | 9U10Z6U3JP | AB01323211-02 |
| AC-18053 | ACM2772454 | ACMC-1CKGN |
| AK140080 | AKOS001017927 | AM84873 |
| ANW-26261 | AX8066432 | CAS-2772-45-4 |
| CHEMBL3183863 | CTK3J6798 | DSSTox_CID_9241 |
| DSSTox_GSID_29241 | DSSTox_RID_78727 | DTXSID7029241 |
| EINECS 220-466-0 | FMUYQRFTLHAARI-UHFFFAOYSA-N | FT-0624735 |
| FT-0741130 | KS-00001002 | KSC496O9R |
| LS-195338 | MCULE-2528008858 | NCGC00247990-01 |
| NCGC00247990-02 | NCGC00247990-03 | NCGC00254226-01 |
| NCGC00260005-01 | Oprea1_366720 | Phenol, 2,4-bis(1-methyl-1-phenylethyl)- |
| Phenol, 2,4-bis(alpha,alpha-dimethylbenzyl)- | Phenol,2,4-bis(1-methyl-1-phenylethyl)- | Q27273223 |
| RTR-012374 | SCHEMBL745012 | TR-012374 |
| Tox21_202456 | Tox21_300317 | UNII-9U10Z6U3JP |
| W-107097 | Z56812043; | ZINC2026035 |
| CAS Number | 106060-52-0, 2772-45-4, 80-43-3, 847-90-5 |
| PubChem Compound | 76013 |