Compound

D0764 | acetaldehyde

Molecular Formula C2H4O
Molecular Weight 44.05
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 18.02±6.38 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL human HepG2 MMP assay Negative IC50 163
MEMBRANE POTENTIAL 6.65±4.48 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

H224: Extremely flammable liquid and vapor [Danger Flammable liquids]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H350: May cause cancer [Danger Carcinogenicity]


P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P281, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P312, P337+P313, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

Aggregated GHS information provided by 3088 companies from 34 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H224 (100%): Extremely flammable liquid and vapor [Danger Flammable liquids]


H302 (63.18%): Harmful if swallowed [Warning Acute toxicity, oral]


H311 (14.28%): Toxic in contact with skin [Danger Acute toxicity, dermal]


H317 (14.28%): May cause an allergic skin reaction [Warning Sensitization, Skin]


H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335 (98.96%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


H341 (13.02%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H350 (12.4%): May cause cancer [Danger Carcinogenicity]


H351 (87.6%): Suspected of causing cancer [Warning Carcinogenicity]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P272, P280, P281, P301+P312, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P312, P321, P322, P330, P333+P313, P337+P313, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H224: Extremely flammable liquid and vapor [Danger Flammable liquids]


H302: Harmful if swallowed [Warning Acute toxicity, oral]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H351: Suspected of causing cancer [Warning Carcinogenicity]


P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P281, P301+P312, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P312, P330, P337+P313, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H224: Extremely flammable liquid and vapor [Danger Flammable liquids]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


H351: Suspected of causing cancer [Warning Carcinogenicity]


H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]


P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P273, P280, P281, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P312, P337+P313, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H224: Extremely flammable liquid and vapor [Danger Flammable liquids]


H302: Harmful if swallowed [Warning Acute toxicity, oral]


H311: Toxic in contact with skin [Danger Acute toxicity, dermal]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H332: Harmful if inhaled [Warning Acute toxicity, inhalation]


H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure


Narcotic effects]


H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H350: May cause cancer [Danger Carcinogenicity]


H360: May damage fertility or the unborn child [Danger Reproductive toxicity]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]


P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P273, P280, P281, P301+P312, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P307+P311, P308+P313, P312, P314, P321, P322, P330, P333+P313, P337+P313, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


P264, P280, P305+P351+P338, and P337+P313; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H224: Extremely flammable liquid and vapor [Danger Flammable liquids]


H302: Harmful if swallowed [Warning Acute toxicity, oral]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H332: Harmful if inhaled [Warning Acute toxicity, inhalation]


H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure


Narcotic effects]


H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H351: Suspected of causing cancer [Warning Carcinogenicity]


H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P281, P301+P312, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P307+P311, P308+P313, P312, P314, P321, P330, P333+P313, P337+P313, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H224: Extremely flammable liquid and vapor [Danger Flammable liquids]


H302: Harmful if swallowed [Warning Acute toxicity, oral]


H315: Causes skin irritation [Warning Skin corrosion/irritation]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure


Narcotic effects]


H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H351: Suspected of causing cancer [Warning Carcinogenicity]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P307+P311, P308+P313, P312, P314, P321, P330, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Organism Test type Route Dose (normalized dose) Effect Source
rat LDLo intraperitoneal 500mg/kg (500mg/kg) Journal of Biological Chemistry. Vol. 152, Pg. 41, 1944.
rabbit LDLo intravenous 300mg/kg (300mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
rabbit LDLo subcutaneous 1200mg/kg (1200mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
mouse LD50 subcutaneous 560mg/kg (560mg/kg) behavioral: general anesthetic Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
rat LD50 oral 661mg/kg (661mg/kg) Agents and Actions, A Swiss Journal of Pharmacology. Vol. 4, Pg. 125, 1974.
frog LDLo intravenous 800mg/kg (800mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
mouse LC50 inhalation 23gm/m3/4H (23000mg/m3) Current Toxicology. Vol. 1, Pg. 47, 1993.
mouse LD50 intraperitoneal 500mg/kg (500mg/kg) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 36, Pg. 101, 1985.
rat LD50 subcutaneous 640mg/kg (640mg/kg) behavioral: general anesthetic Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
human TCLo inhalation 134ppm/30M (134ppm) lungs, thorax, or respiration: other changes JAMA, Journal of the American Medical Association. Vol. 165, Pg. 1908, 1957.
rabbit LD50 skin 3540mg/kg (3540mg/kg) Union Carbide Data Sheet. Vol. 12/13/1963,
mammal (species unspecified) LC50 inhalation 20100mg/m3 (20100mg/m3) Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(7), Pg. 54, 1975.
mouse LD50 oral 900mg/kg (900mg/kg) Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(11), Pg. 57, 1981.
rat LC50 inhalation 13300ppm/4H (13300ppm) National Technical Information Service. Vol. OTS0534485,
hamster LD50 intratracheal 96mg/kg (96mg/kg) Progress in Experimental Tumor Research. Vol. 24, Pg. 162, 1979.
hamster LC50 inhalation 17000ppm/4H (17000ppm) Progress in Experimental Tumor Research. Vol. 24, Pg. 162, 1979.


  • 1-oxapropylene 108796-EP2277864A1 108796-EP2280002A1
    108796-EP2298305A1 108796-EP2298769A1 170111-EP2275413A1
    170111-EP2287156A1 21553-EP2287165A2 21553-EP2314295A1
    21553-EP2314574A1 26915-EP2280009A1 26915-EP2305662A1
    26915-EP2308857A1 26915-EP2314583A1 37566-EP2277867A2
    37566-EP2280003A2 37566-EP2281820A2 37566-EP2284157A1
    37566-EP2286811A1 37566-EP2287159A1 37566-EP2292227A2
    37566-EP2298746A1 37566-EP2298750A1 37566-EP2298754A1
    37566-EP2298758A1 37566-EP2298759A1 37566-EP2298763A1
    37566-EP2298778A1 37566-EP2305664A1 37566-EP2305682A1
    37566-EP2308861A1 37566-EP2308879A1 37566-EP2311802A1
    37566-EP2311803A1 37566-EP2311840A1 37566-EP2374783A1
    37566-EP2377841A1 37566-EP2377842A1 37566-EP2380874A2
    4998-EP0930075A1 4998-EP1441224A2 4998-EP2269979A1
    4998-EP2269988A2 4998-EP2269989A1 4998-EP2269992A1
    4998-EP2270004A1 4998-EP2270005A1 4998-EP2270010A1
    4998-EP2270011A1 4998-EP2270014A1 4998-EP2270113A1
    4998-EP2270114A1 4998-EP2272491A1 4998-EP2272517A1
    4998-EP2272813A2 4998-EP2272825A2 4998-EP2272826A1
    4998-EP2272831A1 4998-EP2272832A1 4998-EP2272834A1
    4998-EP2272839A1 4998-EP2272840A1 4998-EP2272843A1
    4998-EP2272848A1 4998-EP2272935A1 4998-EP2272972A1
    4998-EP2272973A1 4998-EP2275102A1 4998-EP2275105A1
    4998-EP2275395A2 4998-EP2275404A1 4998-EP2275409A1
    4998-EP2275411A2 4998-EP2275412A1 4998-EP2277848A1
    4998-EP2277865A1 4998-EP2277872A1 4998-EP2277878A1
    4998-EP2277880A1 4998-EP2280000A1 4998-EP2280002A1
    4998-EP2280006A1 4998-EP2280007A1 4998-EP2280008A2
    4998-EP2280012A2 4998-EP2281812A1 4998-EP2281824A1
    4998-EP2284146A2 4998-EP2284147A2 4998-EP2284148A1
    4998-EP2284157A1 4998-EP2284160A1 4998-EP2286812A1
    4998-EP2286915A2 4998-EP2287147A2 4998-EP2287153A1
    4998-EP2287158A1 4998-EP2287159A1 4998-EP2287165A2
    4998-EP2287166A2 4998-EP2289868A1 4998-EP2289871A1
    4998-EP2289882A1 4998-EP2289890A1 4998-EP2289893A1
    4998-EP2289894A2 4998-EP2292227A2 4998-EP2292576A2
    4998-EP2292586A2 4998-EP2292589A1 4998-EP2292593A2
    4998-EP2292610A1 4998-EP2292620A2 4998-EP2295401A2
    4998-EP2295407A1 4998-EP2295411A1 4998-EP2295414A1
    4998-EP2295418A1 4998-EP2295426A1 4998-EP2295427A1
    4998-EP2295433A2 4998-EP2295434A2 4998-EP2295435A1
    4998-EP2295437A1 4998-EP2295439A1 4998-EP2298312A1
    4998-EP2298734A2 4998-EP2298736A1 4998-EP2298744A2
    4998-EP2298749A1 4998-EP2298757A2 4998-EP2298758A1
    4998-EP2298759A1 4998-EP2298767A1 4998-EP2298770A1
    4998-EP2298775A1 4998-EP2298778A1 4998-EP2298780A1
    4998-EP2298783A1 4998-EP2299509A1 4998-EP2301544A1
    4998-EP2301911A1 4998-EP2301912A2 4998-EP2301916A2
    4998-EP2301927A1 4998-EP2301929A1 4998-EP2301930A1
    4998-EP2301931A1 4998-EP2301933A1 4998-EP2301935A1
    4998-EP2301940A1 4998-EP2302382A2 4998-EP2302383A2
    4998-EP2305250A1 4998-EP2305627A1 4998-EP2305629A1
    4998-EP2305633A1 4998-EP2305648A1 4998-EP2305652A2
    4998-EP2305660A1 4998-EP2305664A1 4998-EP2305668A1
    4998-EP2305672A1 4998-EP2305674A1 4998-EP2305677A1
    4998-EP2305679A1 4998-EP2305682A1 4998-EP2305684A1
    4998-EP2305685A1 4998-EP2305686A1 4998-EP2305687A1
    4998-EP2305808A1 4998-EP2305825A1 4998-EP2308562A2
    4998-EP2308833A2 4998-EP2308838A1 4998-EP2308840A1
    4998-EP2308841A2 4998-EP2308844A2 4998-EP2308845A2
    4998-EP2308846A2 4998-EP2308848A1 4998-EP2308850A1
    4998-EP2308851A1 4998-EP2308852A1 4998-EP2308861A1
    4998-EP2308867A2 4998-EP2308870A2 4998-EP2308872A1
    4998-EP2308874A1 4998-EP2308879A1 4998-EP2308882A1
    4998-EP2308883A1 4998-EP2308960A1 4998-EP2311796A1
    4998-EP2311797A1 4998-EP2311798A1 4998-EP2311799A1
    4998-EP2311801A1 4998-EP2311802A1 4998-EP2311803A1
    4998-EP2311806A2 4998-EP2311808A1 4998-EP2311818A1
    4998-EP2311820A1 4998-EP2311822A1 4998-EP2311827A1
    4998-EP2311829A1 4998-EP2311830A1 4998-EP2311837A1
    4998-EP2311841A1 4998-EP2311842A2 4998-EP2314295A1
    4998-EP2314574A1 4998-EP2314576A1 4998-EP2314579A1
    4998-EP2314587A1 4998-EP2316470A2 4998-EP2316824A1
    4998-EP2316825A1 4998-EP2316826A1 4998-EP2316829A1
    4998-EP2316831A1 4998-EP2316832A1 4998-EP2316833A1
    4998-EP2316836A1 4998-EP2316974A1 4998-EP2371811A2
    4998-EP2371814A1 4998-EP2372017A1 4998-EP2374454A1
    4998-EP2374780A1 4998-EP2374781A1 4998-EP2374783A1
    4998-EP2374788A1 4998-EP2377841A1 4998-EP2377844A2
    4998-EP2380871A1 75-07-0 A838317
    ACETALD ACETYL GROUP ACMC-20alvc
    AI3-31167 AKOS000120180 Acetaldehyd
    Acetaldehyd [German] Acetaldehyde (natural) Acetaldehyde 10%
    Acetaldehyde Natural Acetaldehyde [UN1089] [Flammable liquid] Acetaldehyde [UN1089] [Flammable liquid]
    Acetaldehyde polymerized Acetaldehyde solution, 40 wt. % in H2O Acetaldehyde solution, 40 wt. % in isopropanol
    Acetaldehyde solution, 5 M in THF Acetaldehyde solution, 50 wt. % (triacetin) Acetaldehyde solution, 50 wt. % in ethanol
    Acetaldehyde solution, natural, 50 wt. % ethanol, FG Acetaldehyde solution, natural, 50 wt. % in ethanol Acetaldehyde solution, natural, 50 wt. % in ethanol, analytical standard;
    Acetaldehyde, 99.5%, extra pure Acetaldehyde, 99.5%, extra pure, AcroSeal(R) Acetaldehyde, >=90.0%, SAJ first grade
    Acetaldehyde, >=99%, FCC Acetaldehyde, >=99%, FCC, stabilized Acetaldehyde, >=99%, FG
    Acetaldehyde, >=99%, meets FCC analytical specification Acetaldehyde, ACS reagent, >=99.5% Acetaldehyde, ReagentPlus(R), 99%
    Acetaldehyde, ReagentPlus(R), >=99.0% (GC) Acetaldehyde, United States Pharmacopeia (USP) Reference Standard Acetaldehyde, analytical standard
    Acetaldehyde, natural, >=99%, FG Acetaldehyde, puriss. p.a., anhydrous, >=99.5% (GC) Acetaldeyde
    Aceteldehyde Acetic ethanol Acetylaldehyde
    Aldehyde C(2) Aldehyde acetique Aldehyde acetique [French]
    Aldeide acetica Aldeide acetica [Italian] Azetaldehyd
    BIDD:ER0621 BRD-K77914232-001-01-3 C00084
    CAS-75-07-0 CCRIS 1396 CH2CHO
    CH3CHO CHEBI:15343 CHEBI:16571
    CHEMBL170365 CTK2H7190 DSSTox_CID_2
    DSSTox_GSID_39224 DSSTox_RID_79423 DTXSID5039224
    EC 200-836-8 EINECS 200-836-8 Epitope ID:145667
    Ethylaldehyde F2190-0651 FEMA No. 2003
    FT-0621719 GO1N1ZPR3B GTPL6277
    HSDB 230 IKHGUXGNUITLKF-UHFFFAOYSA-N InChI=1/C2H4O/c1-2-3/h2H,1H
    KS-00000WLM KSC377C9B LS-1654
    MCULE-6800925955 MFCD00006991 MeCHO
    NATURAL ALDEFRESH NCGC00091753-01 NCGC00260028-01
    NCI-C56326 NSC 7594 NSC-7594
    NSC7594 Octowy aldehyd Octowy aldehyd [Polish]
    Oxidized polyvinyl alcohol Q57695648 Q61457
    RCRA waste no. U001 RCRA waste number U001 RTR-024198
    SC-16387 STL264249 STR01382
    TR-024198 TRA0071966 Tox21_202479
    UN 1089 UN1089 UNII-GO1N1ZPR3B
    WLN: VH1 acetaldehyde acetaldehydes
    acetaldhyde acetic aldehyde acetic hydride
    acetoaldehyde aldehyde an oxidized polyvinyl alcohol
    bmse000647 ethaldehyde ethan-1-one
    ethanal ethanone ethyl aldehyde
    oxidised poly(vinyl alcohol)

    CAS Number 101-48-4, 1632-89-9, 25067-34-9, 4122-13-8, 7440-34-8, 75-07-0
    PubChem Compound 177
    KEGG Compound ID C00084
    ChEBI 15343
    PharmGKB PA166186245