Compound

D0952 | gentian violet

Molecular Formula C25H30ClN3
Molecular Weight 408
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 0.08±0.04 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 0.35 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 1.34±0.11 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]


H351: Suspected of causing cancer [Warning Carcinogenicity]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P201, P202, P264, P270, P273, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]


H350: May cause cancer [Danger Carcinogenicity]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P201, P202, P264, P270, P273, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

Aggregated GHS information provided by 458 companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H302 (99.78%): Harmful if swallowed [Warning Acute toxicity, oral]


H318 (99.78%): Causes serious eye damage [Danger Serious eye damage/eye irritation]


H350 (34.06%): May cause cancer [Danger Carcinogenicity]


H351 (65.94%): Suspected of causing cancer [Warning Carcinogenicity]


H400 (99.78%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (99.78%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P201, P202, P264, P270, P273, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]


H351: Suspected of causing cancer [Warning Carcinogenicity]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P201, P202, P264, P270, P273, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H350: May cause cancer [Danger Carcinogenicity]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P201, P202, P260, P264, P270, P280, P281, P301+P310, P305+P351+P338, P308+P313, P314, P321, P330, P337+P313, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H351: Suspected of causing cancer [Warning Carcinogenicity]


H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P201, P202, P260, P264, P270, P281, P301+P312, P308+P313, P314, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Organism Test type Route Dose (normalized dose) Effect Source
rat LD50 unreported 975mg/kg (975mg/kg) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 43(4), Pg. 102, 1978.
mouse LD50 intraperitoneal 6mg/kg (6mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 1, Pg. 5, 1951.
rat LD50 oral 413mg/kg (413mg/kg) United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0382-0436,
mouse LD50 oral 105mg/kg (105mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 1, Pg. 5, 1951.


  • ((4-bis(p-(dimethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)dimethylammonium chloride (4-(4,4'-Bis(dimethylamino)benzhydrylidene)cyclohexa-2,5-dien-1-ylidene)dimethylammonium chloride (4-(Bis(p-(dimethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)dimethylammonium chloride
    (4-{bis[-(dimethylamino)phenyl]methylene}-2,5-cyclohexadien-1-ylidene)dimethylammonium chloride (4-{bis[4-(dimethylamino)phenyl]methylene}cyclohexa-2,5-dienylidene)dimethylam ine, chloride 12416 Violet
    39393-39-0 4-{bis[4-(dimethylamino)phenyl]methylene}-N,N-dimethylcyclohexa-2,5-dien-1-iminium chloride 4-{bis[4-(dimethylamino)phenyl]methylidene}-N,N-dimethylcyclohexa-2,5-dien-1-iminium chloride
    548-62-9 548-62-9 (comp.) A10245
    AB2000374 AC-12933 ACM39393390
    AKOS000282988 AKOS015901288 ARONIS27044
    AS-49338 Adergon Aizen Crystal Violet
    Aizen Crystal Violet Extra Pure Ammonium, (4-(bis(p-(dimethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)dimethyl-, chloride Andergon
    Aniline Violet Aniline Violet Pyoktanine Atmonil
    Avermin Axur is Axuris
    Badil Basic Violet 3 100 microg/mL in Methanol Basic Violet 3;Gentian Violet;Hexamethylpararosaniline chloride;Methyl Violet 10B
    Basic Violet BN Basic Violet-3 Basic violet 3
    Bismuth Violet Blaues pyoktanin Blaues pyoktanin [German]
    Brilliant Violet 5B C .I. basic violet 3 C-8650
    C-8651 C-8652 C.I. 42555
    C.I. Basic Violet 3 (8CI) C.I. Basic violet 3 C.I.Basic Violet 11:1
    C25H30ClN3 C25H30N3.Cl C25H30N3Cl
    CAS-548-62-9 CCG-39763 CCRIS 2464
    CHEBI:41688 CHEMBL64894 CI 42555
    CI Basic Violet 3 CS-2365 Calcozine Violet 6BN
    Calcozine Violet C Caswell No. 264A Chlorure de methylrosanilinum
    Chlorure de methylrosanilinum [INN-French] Cloruro de metilrosanilina Cloruro de metilrosanilina [INN-Spanish]
    Crystal Violet 10B Crystal Violet 5BO Crystal Violet 6B
    Crystal Violet 6BO Crystal Violet AO Crystal Violet AON
    Crystal Violet BP Crystal Violet BPC Crystal Violet Base
    Crystal Violet Extra Pure Crystal Violet Extra Pure APN Crystal Violet Extra Pure APNX
    Crystal Violet FN Crystal Violet HL2 Crystal Violet O
    Crystal Violet Pure DSC Crystal Violet Pure DSC Brilliant Crystal Violet SS
    Crystal Violet Technical Crystal Violet USP Crystal Violet chloride
    Crystal Violet chloride salt Crystal Violet, 97.0-103.0% Crystal Violet, A.C.S. reagent
    Crystal Violet, ACS reagent, >=90.0% anhydrous basis Crystal Violet, Dye content >=90 % Crystal Violet, JIS special grade
    Crystal Violet, SAJ first grade Crystal Violet, SAJ special grade Crystal Violet, VETRANAL(TM), analytical standard
    Crystal Violet, certified Crystal Violet, certified by the Biological Stain Commission Crystal Violet, for microscopy (Bact., Bot., Hist., Vit.), indicator (pH 0.1-2.0)
    Crystal Violet, indicator for the determination of the redox potential, S. No.: 785 Crystal Violet, micronized Crystal Violet, pure, high purity biological stain
    Crystal Violet, pure, indicator Crystal violet Crystal violet solution
    Crystal violet solution, 1%, aqueous solution Crystal violet, ACS reagent Crystal-violet
    D01046 DSSTox_CID_653 DSSTox_GSID_20653
    DSSTox_RID_75713 DTXSID5020653 EC 208-953-6
    EINECS 208-953-6 EN300-113977 EPA Pesticide Chemical Code 039502
    FT-0628821 GA9809 GNF-PF-880
    GV-Eleven GVS Genapax
    Genapax (TN) Gentersal Gentian Violet
    Gentian Violet solution Gentian Violet solution, for microscopy Gentian Violet, United States Pharmacopeia (USP) Reference Standard
    Gentian Violet, meets USP testing specifications Gentian violet (USP) Gentian violet [USP]
    Gentian violet, 95.0-105.0% Gentian violet, for microscopy (Bact., Hist.) Gentian violet;Hexamethyl pararosaniline chloride
    Gentianaviolett Gentianaviolett [German] Gentiaverm
    Genticid Gentioletten Gram's Crystal Violet Solution
    Gram-Hucker's stain solution (I) HEXAMETHYL-P-ROSANILINE CHLORIDE HMS1920B11
    HMS2091H15 HMS3655D03 HMS500B13
    HSDB 4366 HY-B0324A Hecto Violet R
    Hectograph Violet SR Hectograph violet Hexamethyl Violet
    Hexamethyl p-rosaniline hydrochloride Hexamethyl pararosaniline chloride Hexamethyl-p-rosaniline hydrochloride
    Hexamethylpararosaniline chloride Hexamethylpararosaniline chloride Hidaco Brilliant Crystal Violet
    Hidaco crystal Violet J4Z741D6O5 KS-00000YEO
    KS-000048JJ Kristall-violett Kristall-violett [German]
    LS-1348 M ethyl Violet 10BNS M211
    MCULE-6095016251 MFCD00011750 Meroxyl
    Meroxyl-Wander Meroxylan Meroxylan-Wander
    Methanaminium, N-(4-(bis(4-(dimethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-methyl-, chloride Methanaminium, N-(4-(bis(4-(dimethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-methyl-, chloride (1:1) Methanaminium, N-[4-[bis[4-(dimethylamino)phen yl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride
    Methanaminium, N-[4-[bis[4-(dimethylamino)phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride Methanaminium, N-[4-[bis[4-(dimethylamino)phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride (1:1) Methanaminium,N-[4-[bis[4-(dimethylamino)phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride
    Methanaminium,N-[4-[bis[4-(dimethylamino)phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-,chloride Methyl Violet 10B Methyl Violet 10BD
    Methyl Violet 10BK Methyl Violet 10BN Methyl Violet 10BNS
    Methyl Violet 10BO Methyl Violet 5BNO Methyl Violet 5BO
    Methyl Violet 6B (biological stain) Methylrosanilinchlorid [German] Methylrosaniline chloride
    Methylrosanilini chloridum Methylrosanilinii chloridum Methylrosanilinii chloridum [INN-Latin]
    Methylrosanilinium chloride (JP17/INN) Methylrosanilinium chloride [INN] Methylrosanilinium chloride, European Pharmacopoeia (EP) Reference Standard
    Methylrosanilinium for system suitability, European Pharmacopoeia (EP) Reference Standard Methylrosanilinum chloratum Methylviolett
    Methylviolett [German] Metilrosanilinio cloruro Metilrosanilinio cloruro [DCIT]
    Mitsui Crystal Violet N-(-4-{bis[4-(dimethylamino)phenyl]methylene}2,5-cyclohexadien-1-ylidene)-N-methyltrimethanaminium chloride N-(4-(Bis(4-(dimethylamino)phenyl)methylene)cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride
    N-(4-(bis(4-(dimethylamino)phenyl)methylene)cyclohexa-2,5-dienylidene)-N-methylmethanaminium chloride N-(4-{bis[4-(dimethylamino)phenyl]methylene}-2,5-cyclohexadien-1-ylidene)-N-methylmethanaminium chloride N-(4-{bis[4-(dimethylamino)phenyl]methylene}cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium;
    N-(4-{bis[4-(dimethylamino)phenyl]methylidene}cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride NCGC00091112-01 NCGC00091112-02
    NCGC00091112-09 NCGC00094687-01 NCGC00094687-02
    NCGC00254524-01 NCGC00259311-01 NCI-C55969
    NSC 3090 NSC-3090 NSC-757050
    NSC3090 NSC757050 Oxiuran
    Oxycolor Oxyozyl Paper Blue R
    Pararosaniline, N,N,N',N',N'',N''-hexamethyl-, chloride Pararosaniline,N,N',N',N'',N''-hexamethyl-, chloride Pharmakon1600-01500315
    Plastoresin Violet 5BO Pyoktanin Pyoverm
    Q420705 SBB009016 SCHEMBL9171
    SPECTRUM1500315 SR-05000001923 SR-05000001923-1
    ST50411633 SW219351-1 Sentry aq mardel quick aid
    Tox21_111084 Tox21_111084_1 Tox21_201762
    Tox21_300571 UNII-H2G44K8M7S component ZXJXZNDDNMQXFV-UHFFFAOYSA-M UNII-J4Z741D6O5
    Vermicid Vianin Viocid
    Violet 5BO Violet 6BN Violet CP
    Violet XXIII Violet cristallise Violet gencianova
    Violet gencianova [Czech] Violet krystalova Violet krystalova [Czech]
    Violet zasadita 3 Violet zasadita 3 [Czech] WLN: L6Y DYJ AUYR DN1&1&R DN1&1& DUK1&1 &Q &G
    Z2786051713 ZXJXZNDDNMQXFV-UHFFFAOYSA-M [4-[bis[4-(dimethylamino)phenyl]methylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium;chloride
    brilliant violet 58 chlorure de methylrosanilinium cryst al violet fn
    genetian violet gentian violet hexamethylparaosaniline chloride
    meroxylanwander methylrosanilinium chloride s1917
    tris(4-(dimethylamino)phenyl)methylium chloride

    CAS Number 14426-25-6, 39393-39-0, 52080-58-7, 548-62-9, 60662-33-1, 8004-87-3
    PubChem Compound 11057
    KEGG Drug D01046
    ChEBI 41688