Compound

D0816 | bromocriptine mesylate

Molecular Formula C33H44BrN5O8S
Molecular Weight 750.7
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 11.19±2.78 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 13.5 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 12.57±1.60 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Warning

Aggregated GHS information provided by 11 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


Reported as not meeting GHS hazard criteria by 1 of 11 companies. For more detailed information, please visit ECHA C&L website


Of the 5 notification(s) provided by 10 of 11 companies with hazard statement code(s):


H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]


H332 (40%): Harmful if inhaled [Warning Acute toxicity, inhalation]


H361 (50%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]


H400 (50%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (80%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P201, P202, P261, P264, P270, P271, P273, P281, P301+P312, P304+P312, P304+P340, P308+P313, P312, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (+)-Bromocriptine methanesulfonate (5'a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione mesylate (5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-2'-(propan-2-yl)-3',6',18-trioxoergotaman methanesulfonate
    (5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman methanesulfonate (salt) (5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman methanesulfonate (5xi,5'alpha)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-3',6',18-trioxoergotaman methanesulfonate (salt)
    (5xi,5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman methanesulfonate (salt) (6aR,9R)-5-Bromo-N-[(2R,5S,10aS,10bS)-10b-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quin .alpha.-Ergocryptine, methanesulfonate
    2-Bromine-alpha-ergocryptine methanesulfonate 2-Bromo alpha-Ergocryptine Mesylate 2-Bromo-.alpha.-ergocryptine monomethanesulfonate
    2-Bromo-12'-hydroxy-5'alpha-isobutyl-2'-isopropylergotaman-3',6',18-trione monomethanesulphonate 2-Bromo-a-ergocryptine methanesulfonate salt 2-Bromo-alpha-ergocryptine mesylate
    2-Bromo-alpha-ergocryptine methanesulfonate 2-Bromo-alpha-ergokryptine-mesilate 2-Bromo-alpha-ergokryptine-mesilate [German]
    2-Bromoergocryptine Mesylate 2-Bromoergocryptine monomethanesulfonate (salt) 2-bromo-12'-hydroxy-5'a-isobutyl-2'-isopropylergotaman-3',6',18-trione monomethanesulphonate;
    22260-51-1 93201-EP2272825A2 93201-EP2305633A1
    AKOS015896276 B 2134 B6298
    BROMOCRIPTINE MESYLATE Bagren Bromergon
    Bromocriptine (mesylate) Bromocriptine mesilate Bromocriptine mesilate (JP17)
    Bromocriptine mesylate (USP) Bromocriptine mesylate [USAN:USP] Bromocriptine mesylate [USAN]
    Bromocriptine methanesulfonate Bromocryptine mesylate Bromocryptine methanesulfonate
    C32H40BrN5O5.CH3SO3H C32H40BrN5O5.CH4O3S CAS-22260-51-1
    CB 154 CB 154 methanesulfonate (salt) CB-154
    CB-154 mesylate CCG-220121 CCG-221475
    CHEBI:3182 CHEMBL1200503 CS-6048
    Cycloset D00780 DSSTox_CID_197
    DSSTox_GSID_20197 DSSTox_RID_75426 DTXSID6020197
    EINECS 244-881-1 EU-0100171 Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, monomethanesulfonate (salt), (5'alpha)-
    FFP983J3OD HMS1568I04 HMS3260D03
    HMS3411K09 HMS3675K09 HMS3712I04
    HY-12705A LP00171 LS-7234
    NCGC00257268-01 NCGC00260856-01 NOJMTMIRQRDZMT-GSPXQYRGSA-N
    NSC-169774 NSC169774 Parlodel
    Parlodel (TN) Pravidel Prestwick_771
    Q27105974 SCHEMBL40559 SR-01000075356
    SR-01000075356-1 SR-01000597796 SR-01000597796-1
    SR-01000597796-2 Tox21_303597 Tox21_500171
    UNII-FFP983J3OD alpha-Ergocryptine, 2-bromo-, methanesulfonate oline-9-carboxamide methanesulfonate

    CAS Number 22260-51-1
    PubChem Compound 31100
    KEGG Drug D00780
    ChEBI 3182