Compound

D1154 | tyrphostin 23

Molecular Formula C10H6N2O2
Molecular Weight 186.17
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 17.70±6.46 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 17.34 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Warning

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.


H371 (100%): May cause damage to organs [Warning Specific target organ toxicity, single exposure]


H373 (100%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P260, P264, P270, P309+P311, P314, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (3,4-Dihydroxybenzylidene)malononitrile (3,4-Dihydroxyphenyl)methylene propanedinitrile (3,4-dihydroxybenzylidene)propanedinitrile
    118409-57-7 2-(3,4-Dihydroxy-benzylidene)-malononitrile 2-(3,4-dihydroxybenzylidene)malononitrile
    2-[(3,4-dihydroxyphenyl)methylidene]propanedinitrile 2085AH 2773AH
    3,4-(Dihydroxybenzylidene)malononitrile 3,4-Dihydroxybenzylidene malononitrile 3,4-dihydroxybenzylidenemalononitrile
    4CH-004570 AB0152128 AC-30286
    ACMC-20dhi7 AG 18 AG 18 (Tyrphostin 23)
    AG-18 AG18;Tyrphostin 23 AK326227
    AKOS005715658 AOB5120 AS-69033
    BBL008106 BCP06838 BDBM4339
    BMK1-B11 BRD-K49657628-001-02-3 BRD-K49657628-001-03-1
    BRD-K49657628-001-05-6 BiomolKI2_000021 BiomolKI_000011
    C10H6N2O2 CAS-118409-57-7 CCG-100615
    CHEBI:92862 CHEMBL76904 CS-1387
    CTK4B0662 DB-093180 DSSTox_CID_25215
    DSSTox_GSID_45215 DSSTox_RID_80754 DTXSID9045215
    EC-000.2086 EU-0101160 EX-A901
    FT-0675716 HMS2233I22 HMS3263H21
    HMS3266E18 HMS3369M02 HMS3414G15
    HMS3653D19 HMS3678G15 HSCI1_000108
    HY-15644 J-003744 KS-0000185K
    LP01160 LS-172378 Lopac-T-7165
    Lopac0_001160 MCK100778 MCULE-8159081339
    MFCD00133899 MLS002153315 NCGC00016043-01
    NCGC00016043-02 NCGC00016043-03 NCGC00016043-04
    NCGC00016043-05 NCGC00016043-06 NCGC00016043-07
    NCGC00016043-08 NCGC00024615-01 NCGC00024615-02
    NCGC00024615-03 NCGC00024615-04 NCGC00261845-01
    Oprea1_072726 Propanedinitrile, ((3,4-dihydroxyphenyl)methylene)- Propanedinitrile,2-[(3,4-dihydroxyphenyl)methylene]-
    Q27164614; RG 50810 RG-50810
    RG-50810 RT-016155 RV0GCD31OJ
    SC-95402 SCHEMBL241922 SMR001230729
    SR-01000075506 SR-01000075506-1 SR-01000075506-3
    SR-01000075506-6 STL139213 SW219523-1
    T 7165 TX 825 Tocris-0493
    Tox21_110287 Tox21_110287_1 Tox21_501160
    Tyrphostin 23 Tyrphostin 23, >=98% Tyrphostin A23
    Tyrphostin AG18 Tyrphostin RG50810 UNII-RV0GCD31OJ
    VTJXFTPMFYAJJU-UHFFFAOYSA-N W-5079 ZINC15331
    [(3,4-Dihydroxyphenyl)methylene]-propenedinitrile ag-18-tyrphostin-23 ag18
    alpha-Cyano-(3,4-dihydroxy)cinnamonitrile benzylidenemalononitrile (BMN) deriv. 23 cid_2052
    s8009 tyrphostin-23

    CAS Number 118409-57-7, 119736-65-1
    PubChem Compound 2052