Compound
D1154 | tyrphostin 23
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 17.70±6.46 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 17.34 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. H371 (100%): May cause damage to organs [Warning Specific target organ toxicity, single exposure] H373 (100%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P260, P264, P270, P309+P311, P314, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| (3,4-Dihydroxybenzylidene)malononitrile | (3,4-Dihydroxyphenyl)methylene propanedinitrile | (3,4-dihydroxybenzylidene)propanedinitrile |
| 118409-57-7 | 2-(3,4-Dihydroxy-benzylidene)-malononitrile | 2-(3,4-dihydroxybenzylidene)malononitrile |
| 2-[(3,4-dihydroxyphenyl)methylidene]propanedinitrile | 2085AH | 2773AH |
| 3,4-(Dihydroxybenzylidene)malononitrile | 3,4-Dihydroxybenzylidene malononitrile | 3,4-dihydroxybenzylidenemalononitrile |
| 4CH-004570 | AB0152128 | AC-30286 |
| ACMC-20dhi7 | AG 18 | AG 18 (Tyrphostin 23) |
| AG-18 | AG18;Tyrphostin 23 | AK326227 |
| AKOS005715658 | AOB5120 | AS-69033 |
| BBL008106 | BCP06838 | BDBM4339 |
| BMK1-B11 | BRD-K49657628-001-02-3 | BRD-K49657628-001-03-1 |
| BRD-K49657628-001-05-6 | BiomolKI2_000021 | BiomolKI_000011 |
| C10H6N2O2 | CAS-118409-57-7 | CCG-100615 |
| CHEBI:92862 | CHEMBL76904 | CS-1387 |
| CTK4B0662 | DB-093180 | DSSTox_CID_25215 |
| DSSTox_GSID_45215 | DSSTox_RID_80754 | DTXSID9045215 |
| EC-000.2086 | EU-0101160 | EX-A901 |
| FT-0675716 | HMS2233I22 | HMS3263H21 |
| HMS3266E18 | HMS3369M02 | HMS3414G15 |
| HMS3653D19 | HMS3678G15 | HSCI1_000108 |
| HY-15644 | J-003744 | KS-0000185K |
| LP01160 | LS-172378 | Lopac-T-7165 |
| Lopac0_001160 | MCK100778 | MCULE-8159081339 |
| MFCD00133899 | MLS002153315 | NCGC00016043-01 |
| NCGC00016043-02 | NCGC00016043-03 | NCGC00016043-04 |
| NCGC00016043-05 | NCGC00016043-06 | NCGC00016043-07 |
| NCGC00016043-08 | NCGC00024615-01 | NCGC00024615-02 |
| NCGC00024615-03 | NCGC00024615-04 | NCGC00261845-01 |
| Oprea1_072726 | Propanedinitrile, ((3,4-dihydroxyphenyl)methylene)- | Propanedinitrile,2-[(3,4-dihydroxyphenyl)methylene]- |
| Q27164614; | RG 50810 | RG-50810 |
| RG-50810 | RT-016155 | RV0GCD31OJ |
| SC-95402 | SCHEMBL241922 | SMR001230729 |
| SR-01000075506 | SR-01000075506-1 | SR-01000075506-3 |
| SR-01000075506-6 | STL139213 | SW219523-1 |
| T 7165 | TX 825 | Tocris-0493 |
| Tox21_110287 | Tox21_110287_1 | Tox21_501160 |
| Tyrphostin 23 | Tyrphostin 23, >=98% | Tyrphostin A23 |
| Tyrphostin AG18 | Tyrphostin RG50810 | UNII-RV0GCD31OJ |
| VTJXFTPMFYAJJU-UHFFFAOYSA-N | W-5079 | ZINC15331 |
| [(3,4-Dihydroxyphenyl)methylene]-propenedinitrile | ag-18-tyrphostin-23 | ag18 |
| alpha-Cyano-(3,4-dihydroxy)cinnamonitrile | benzylidenemalononitrile (BMN) deriv. 23 | cid_2052 |
| s8009 | tyrphostin-23 |
| CAS Number | 118409-57-7, 119736-65-1 |
| PubChem Compound | 2052 |