D0946 | folpet
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 8.25±0.54 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 14.13 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 33.72±20.15 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
   |
Warning |
H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] H351: Suspected of causing cancer [Warning Carcinogenicity] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] |
P201, P202, P261, P264, P271, P272, P273, P280, P281, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P321, P333+P313, P337+P313, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
Aggregated GHS information provided by 2620 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation] H351 (100%): Suspected of causing cancer [Warning Carcinogenicity] H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P261, P264, P271, P272, P273, P280, P281, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P321, P333+P313, P337+P313, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] H351: Suspected of causing cancer [Warning Carcinogenicity] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] |
P201, P202, P261, P264, P271, P272, P273, P280, P281, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P321, P333+P313, P337+P313, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Danger |
H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H351: Suspected of causing cancer [Warning Carcinogenicity] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] |
P201, P202, P260, P261, P271, P272, P280, P281, P284, P302+P352, P304+P340, P308+P313, P310, P320, P321, P333+P313, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LDLo | skin | 5gm/kg (5000mg/kg) | Journal of the American College of Toxicology. Vol. 9, Pg. 642, 1991. | |
| rat | LD50 | unreported | > 10gm/kg (10000mg/kg) | Residue Reviews. Vol. 36, Pg. 240, 1971. | |
| rabbit | LD50 | oral | 1115mg/kg (1115mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(5), Pg. 50, 1974. | |
| mouse | LD50 | intraperitoneal | 80mg/kg (80mg/kg) | behavioral: convulsions or effect on seizure threshold | Acta Biologica et Medica Germanica. Vol. 7, Pg. 502, 1961. |
| rat | LC50 | inhalation | > 5gm/m3/2H (5000mg/m3) | Toxicology and Applied Pharmacology. Vol. 45, Pg. 320, 1978. | |
| mouse | LD50 | oral | 1546mg/kg (1546mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(5), Pg. 50, 1974. | |
| mouse | LD50 | unreported | 750mg/kg (750mg/kg) | Acta Biologica et Medica Germanica. Vol. 1, Pg. 450, 1958. | |
| rabbit | LD50 | skin | > 22600mg/kg (22600mg/kg) | Pesticide Manual. Vol. 9, Pg. 431, 1991. | |
| rat | LD50 | intraperitoneal | 68400ug/kg (68.4mg/kg) | Journal of Toxicology and Environmental Health. Vol. 9, Pg. 867, 1982. | |
| mouse | LC50 | inhalation | > 6gm/m3/2H (6000mg/m3) | Toxicology and Applied Pharmacology. Vol. 45, Pg. 320, 1978. | |
| rat | LD50 | oral | 2636mg/kg (2636mg/kg) | National Technical Information Service. Vol. OTS0533649-9, | |
| 133-07-3 | 133F073 | 1H-Isoindole-1,3(2H)-dione, 2-((trichloromethyl)thio)- |
| 1H-Isoindole-1,3(2H)-dione, 2-[(trichloromethyl)thio]- | 2-((Trichloromethyl)thio)-1H-isoindole-1,3(2H)-dione | 2-((Trichloromethyl)thio)isoindoline-1,3-dione |
| 2-(Trichloromethylsulfanyl)isoindole-1,3-dione | 2-(trichloromethylthio)isoindole-1,3-dione | 2-(trichloromethylthio)isoindoline-1,3-dione |
| 2-[(Trichloromethyl)sulfanyl]-1H-isoindole-1,3(2H)-dione | 2-[(Trichloromethyl)sulfanyl]-1H-isoindole-1,3(2H)-dione # | 2-[(Trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione |
| 2-[(Trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione, 9CI | 2-[(trichloromethyl)sulfanyl]-2,3-dihydro-1H-isoindole-1,3-dione | 5-21-11-00118 (Beilstein Handbook Reference) |
| A806547 | AC-997 | AI3-26539 |
| AKOS015895774 | Acryptan | BRN 0193373 |
| C-34942 | C18860 | C9H4Cl3NO2S |
| CAS-133-07-3 | CC-28811 | CCRIS 1036 |
| CHEBI:82019 | CHEMBL1883819 | CS-0013944 |
| Caswell No. 464 | Cosan I | Cosan T |
| DSSTox_CID_1385 | DSSTox_GSID_21385 | DSSTox_RID_76127 |
| DTXSID0021385 | EINECS 205-088-6 | ENT 26539 |
| EPA Pesticide Chemical Code 081601 | FCH2709964 | FT-0659392 |
| Faltan | Faltex | Folnit |
| Folpan | Folpel | Folpel [French] |
| Folpet | Folpet 10 microg/mL in Cyclohexane | Folpet 100 microg/mL in Cyclohexane |
| Folpet [ANSI:BSI:ISO] | Folpet, PESTANAL(R), analytical standard | Folpex |
| Ftalan | Fungitrol | Fungitrol 11 |
| Fungitrol II | HKIOYBQGHSTUDB-UHFFFAOYSA-N | HSDB 2651 |
| HY-B1878 | InChI=1/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4; | Intercide TMP |
| J-006303 | LS-7733 | MCULE-7604769697 |
| MFCD00047303 | Murphy's rose fungicide | N-((Trichloromethyl)thio)-Phthalimide |
| N-(TRICHLOROMETHYL)THIOPHTHALIMIDE | N-(Trichlor-methylthio)-phthalamid | N-(Trichlor-methylthio)-phthalamid [German] |
| N-(Trichlormethylthio)phthalimide | N-(Trichloromethanesulphenyl)phthalimide | N-(Trichloromethylmercapto)phthalimide |
| N-(Trichloromethylthio)phthalimide | N-(trichloromethanesulfenyl)phthalimide | N-(trichloromethyl)-thiophthalimide |
| N-[(Trichloromethyl)thio]-Phthalimide | N-[(Trichloromethyl)thio]phthalimide | NCGC00168313-01 |
| NCGC00168313-02 | NCGC00168313-03 | NCGC00254978-01 |
| NCGC00259536-01 | O669 | Ortho phaltan 50W |
| Orthophaltan | PHALTAN | PHTHALIC ACID,IMIDE,N-TRICHLOROMETHYL SULFENYL |
| Phaltane | Phalton | Phthalimide, N-((trichloromethyl)thio)- |
| Phthalimide, N-[(trichloromethyl)thio]- | Phthaltan | Q426485 |
| SCHEMBL19853 | Spolacid | Thiophal |
| Tox21_201987 | Tox21_301077 | Trichlormethylthioimid kyseliny ftalove |
| Trichlormethylthioimid kyseliny ftalove [Czech] | Trichloromethyl(thio)phthalimide | Trichloromethylthiophthalimide |
| Trifol | Troysan anti-mildew O | UNII-X5NFK36917 |
| Vinicoll | X5NFK36917 | ZINC2041008 |