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2021 MitoTox | (CC BY-NC 4.0)
Compound

D1155 | vatalanib

Molecular Formula C20H15ClN4
Molecular Weight 346.8
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 25.60±4.41 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 30.83 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 20.73±14.69 rat hepatocytes MMP assay decrease IC50 163


  • (4-chlorophenyl)-(4-pyridin-4-ylmethyl-phthalazin-1-yl)amine (4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine (A) PTK787
    1 -(4-Chloroanilino)-4-(4-pyridylmethyl)phthalazine 1-(4-Chloranilino)-4-(4-pyridylmethyl)-phthalazin 1-(4-chlor-anilino)-4-(pyridin-4-yl-methyl)-phthalazine
    1-(4-chloranilino)-4-(4-pyridylmethyl)-phthalazine 1-(4-chloroanilino)-4-(4-pyridylmethyl)phthalazine 1-Phtalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-
    1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)- 1-Phthalazinamine,N-(4-chlorophenyl)-4-(4-pyridinylmethyl)- 139368-EP2270008A1
    139368-EP2292617A1 141V543 212141-54-3
    5DX9U76296 A1778 A815203
    AB0019678 AB01275455-01 AB1004881
    AC-25025 ACT06794 AKOS015896483
    API0004576 AS-17435 BAY-86-5127
    BCP16436 BCPP000021 BDBM4851
    BIFK0006 BRD-K70163715-001-02-8 C20H15ClN4
    CAS-212141-54-3 CCG-220471 CGP 79787
    CGP-7978 CGP-79787 CGP-797870
    CGP79787 CHEBI:90620 CHEMBL101253
    CS-5248 CTK4E6114 D06285
    DB-066452 DB04879 DSSTox_CID_26919
    DSSTox_GSID_46919 DSSTox_RID_82015 DTXSID2046919
    EX-A1398 F9995-0196 FT-0657115
    GTPL5705 HMS2089D11 HMS3713O04
    HMS3745G07 HY-10203 K-222584
    Kinome_3657 LS-187006 LS-187641
    MCULE-3078477385 N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-1-phthalazinamine
    N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phtalazin-1-amine N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine N-(p-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine;
    NCGC00181350-01 NCGC00181350-03 NCGC00181350-06
    NVP-PTK787 PTK-787 PTK/ZK
    PTK787 Pynasunate Q7917084
    QCR-126 RT-016221 SB16582
    SCHEMBL18286 SR-05000001457 SR-05000001457-1
    SR-05000001457-2 Tox21 112808 Tox21_112808
    Tox21_112808_1 UNII-5DX9U76296 VU0549317-1
    Vatalanib Vatalanib (USAN/INN) Vatalanib (free base)
    Vatalanib [USAN:INN] Vatalanib base Vatalanib free base
    Vatalinib YCOYDOIWSSHVCK-UHFFFAOYSA-N ZINC7460
    ZK-222584 ZK-232934 ZK222584
    ZX-AFC002994 cid_151194

    CAS Number 212141-51-0, 212141-54-3, 212142-18-2
    PubChem Compound 151194
    ChEBI 90620