D0733 | 4-cumylphenol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 3.70±0.82 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 3.55 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 48.02±11.61 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Warning |
Aggregated GHS information provided by 133 companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 1 of 133 companies. For more detailed information, please visit ECHA C&L website Of the 13 notification(s) provided by 132 of 133 companies with hazard statement code(s): H302 (10.61%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (87.88%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (90.15%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (87.12%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P264, P270, P281, P301+P312, P308+P313, P314, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| frog | LD50 | oral | 335mg/kg (335mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 12(12), Pg. 44, 1968. | |
| (alpha, alpha-dimethylbenzyl) phenol, p- | 1OH; | 2-(4'-Hydroxyphenyl)-2-phenylpropane |
| 2-Phenyl-2-(4-hydroxyphenyl)propane | 2-Phenyl-2-(p-hydroxyphenyl)propane | 2RLA3OL3QT |
| 2zas | 4-(.alpha.,.alpha.-Dimethylbenzyl)phenol | 4-(1-Methyl-1-Phenethyl) Phenol |
| 4-(1-Methyl-1-phenethyl)phenol | 4-(1-Methyl-1-phenyl-ethyl)-phenol | 4-(1-Methyl-1-phenylethyl)-phenol |
| 4-(1-Methyl-1-phenylethyl)phenol | 4-(2-PHENYLISOPROPYL)PHENOL | 4-(2-Phenylisopropyl) phenol |
| 4-(2-phenylpropan-2-yl)phenol | 4-(Dimethylphenylmethyl)phenol | 4-(alpha,alpha-Dimethylbenzyl)phenol |
| 4-Cumylphenol | 4-Cumylphenol, 99% | 4-Hydroxydiphenyldimethylmethane |
| 4-Isopropylphenyl phenol | 4-alpha-Cumylphenol | 599-64-4 |
| ACMC-1AOGA | AI3-08269 | AKOS000120751 |
| ANW-33399 | AS-57116 | BDBM29609 |
| BIDD:ER0173 | BRD-K94049994-001-01-5 | BRN 1870517 |
| C14258 | CAS-599-64-4 | CCRIS 8908 |
| CHEBI:35092 | CHEMBL194805 | CTK3J2730 |
| Cambridge id 5142949 | Cumyl phenol (Related) | Cumylphenol, p- |
| DB-072734 | DB06902 | DSSTox_CID_2536 |
| DSSTox_GSID_22536 | DSSTox_RID_76617 | DTXSID3022536 |
| EC 209-968-0 | EINECS 209-968-0 | F0020-1559 |
| FT-0616686 | HMS1540M04 | HMS3604L17 |
| HSDB 8089 | KS-000010UM | KSC-19-030 |
| KSC492O3B | KUC105982N | LS-104498 |
| LS-104913 | MCULE-5968866162 | MFCD00002365 |
| NCGC00090941-01 | NCGC00090941-02 | NCGC00090941-03 |
| NCGC00090941-04 | NCGC00090941-05 | NCGC00253961-01 |
| NCGC00258849-01 | NE10182 | NSC 6237 |
| NSC-6237 | NSC6237 | Phenol, 4-(1-methyl-1-phenethyl)- |
| Phenol, 4-(1-methyl-1-phenethyl)- (9CI) | Phenol, 4-(1-methyl-1-phenylethyl)- | Phenol, 4-(1-methyl-1-phenylethyl)- |
| Phenol, p-(.alpha.,.alpha.-dimethylbenzyl)- | Phenol, p-(alpha, alpha-dimethylbenzyl)- | Phenol, p-(alpha,alpha-dimethylbenzyl)- |
| Phenol,.alpha.-dimethylbenzyl)- | Q27095806 | QBDSZLJBMIMQRS-UHFFFAOYSA-N |
| RT-000950 | SBB043700 | SCHEMBL51117 |
| ST029283 | STK831902 | TRA0094532 |
| TimTec1_002380 | Tox21_201297 | Tox21_300056 |
| UNII-2RLA3OL3QT | UNII-E76192MWPA component QBDSZLJBMIMQRS-UHFFFAOYSA-N | W-105293 |
| Z57068819 | ZINC1085204 | [1, ar'-(1-methylethyl)- |
| p-(.alpha.,.alpha.-Dimethylbenzyl)phenol | p-(.alpha.-Cumenyl)phenol | p-(.alpha.-Cumyl)phenol |
| p-(alpha,alpha-Dimethylbenzyl)phenol | p-(alpha-Cumenyl)phenol | p--cumylphenol |
| p-Cumyl phenol | p-Cumylphenol | p-Hydroxy-2,2-diphenylpropane |
| p-[alpha,alpha-dimethylbenzyl)phenol | para-cumylphenol | paracumylphenol |