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Compound

D0675 | 2-isovaleryl-1,3-indanedione

Molecular Formula C14H14O3
Molecular Weight 230.26
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 5.24±0.90 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 56.23 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 22.25±11.09 rat hepatocytes MMP assay decrease IC50 163

Organism Test type Route Dose (normalized dose) Effect Source
rat LDLo oral 100mg/kg (100mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 160, 1944.
rabbit LDLo oral 150mg/kg (150mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 160, 1944.


  • 1, 2-isovaleryl- 1,3-Indandione, 2-isovaleryl- 1H-Indene-1, 2-(3-methyl-1-oxobutyl)-
    1H-Indene-1,3(2H)-dione, 2-(3-methyl-1-oxobutyl)- 1H-Indene-1,3(2H)-dione, 2-(3-methyl-1-oxobutyl)- (9CI) 2,3-Dihydro-2-(3-methyl-1-oxobutyl)-1H-indene-1,3-dione
    2-(3-methylbutanoyl)-1H-indene-1,3(2H)-dione 2-(3-methylbutanoyl)-2,3-dihydro-1H-indene-1,3-dione 2-(3-methylbutanoyl)-2-hydrocyclopenta[1,2-a]benzene-1,3-dione;
    2-(3-methylbutanoyl)indene-1,3-dione 2-Isopentanoyl-1,3-indanedione 2-Isovaleryl-1,3-indandion
    2-Isovaleryl-1,3-indandione 2-Isovaleryl-1,3-indanedione 2-Isovaleryl-1.3-indanedione
    2-Isovalerylindan-1,3-dione 2-Isovalerylindane-1,3-dione 2V8VCY004E
    83-28-3 AI3-00366 AKOS015994348
    BRN 2116374 CAS-83-28-3 CHEMBL3186888
    CTK3I9529 Caswell No. 515 DSSTox_CID_22509
    DSSTox_GSID_42509 DSSTox_RID_80045 DTXSID8042509
    EINECS 201-464-9 EPA Pesticide Chemical Code 067702 HSDB 7118
    Isoval Isovaleryl indandione KS-000028PS
    LS-81212 MCULE-9149823750 MS-6623
    Motomco tracking powder NCGC00255947-01 NSC 404427
    NSC-404427 NSC-5754 NSC404427
    NSC5754 PVWMAOPFDINGAY-UHFFFAOYSA-N Q27255646
    SBB062049 SCHEMBL353367 Tox21_301261
    UNII-2V8VCY004E VALONE WLN: L56 BV DV CHJ CV1Y1&1
    ZINC100682446

    CAS Number 23710-76-1, 83-28-3, 88590-46-9
    PubChem Compound 6733