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| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 45.79±2.99 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 39.04 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 26.13±2.13 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Danger |
Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory. H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P301+P310, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| 2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid | 2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid | 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID |
| 3,3',5,5'-TETRAIODOTHYROACETIC ACID | 3,3,5,5-Tetraiodothyroacetic acid | 3,5,3',5'-Tetraiodo Thyroacetic Acid |
| 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneacetic acid | 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenylacetic acid | 67-30-1 |
| AKOS027427106 | Acetic acid, (4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)- | Acetic acid, (4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)- (8CI) |
| Acide 3,5,3',5'-tetraiodothyroacetique | Acide 3,5,3',5'-tetraiodothyroacetique [French] | BRD-K71437774-001-02-3 |
| BSPBio_002144 | Benzeneacetic acid, 3,5-diiodo-4-(4-hydroxy-3,5-diiodophenoxy)- | Benzeneacetic acid, 4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo- |
| CAS-67-30-1 | CCG-39583 | CHEBI:131194 |
| CHEMBL549748 | CTK8F4763 | DB01751 |
| DSSTox_CID_28160 | DSSTox_GSID_48186 | DSSTox_RID_82722 |
| DTXSID5048186 | DivK1c_006947 | EINECS 200-649-1 |
| FT-0675069 | KBio1_001891 | KBio2_000889 |
| KBio2_003457 | KBio2_006025 | KBio3_001644 |
| KBioGR_001140 | KBioSS_000889 | KS-00001854 |
| LS-28756 | NCGC00095962-01 | NCGC00095962-02 |
| NCGC00257434-01 | PA7UX1FFYQ | PPJYSSNKSXAVDB-UHFFFAOYSA-N |
| Q27092911 | SC-83104 | SCHEMBL365951 |
| SPBio_000589 | SPECTRUM1500775 | STL451043 |
| SpecPlus_000851 | Spectrum2_000545 | Spectrum3_000612 |
| Spectrum4_000610 | Spectrum5_001610 | Spectrum_000409 |
| T4A | Tetrac | Tetraiodothyroacetic acid |
| Thyroacetic acid, 3,3',5,5'-tetraiodo- | Tox21_303492 | UNII-PA7UX1FFYQ |
| ZINC8681598 | [4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic Acid (Tetraiodothyroacetic Acid); | [4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid |
| DrugBank Name | 3,3',5,5'-tetraiodothyroacetic acid |
| DrugBank | DB01751 |
| CAS Number | 67-30-1 |
| PubChem Compound | 65552 |
| ChEBI | 131194 |