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Compound

D0655 | 2,6-di-tert-butyl-4-nitrophenol

Molecular Formula C14H21NO3
Molecular Weight 251.32
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 0.17±0.05 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 0.11 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 0.29±0.30 rat hepatocytes MMP assay decrease IC50 163

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 intraperitoneal 700mg/kg (700mg/kg) behavioral: somnolence (general depressed activity) Toxicology and Applied Pharmacology. Vol. 3, Pg. 713, 1961.
guinea pig LD50 intraperitoneal 580mg/kg (580mg/kg) behavioral: somnolence (general depressed activity) Toxicology and Applied Pharmacology. Vol. 3, Pg. 713, 1961.
rat LD50 oral 250mg/kg (250mg/kg) "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 4, Pg. 141, 1969.
guinea pig LD50 oral 800mg/kg (800mg/kg) behavioral: somnolence (general depressed activity) Toxicology and Applied Pharmacology. Vol. 3, Pg. 713, 1961.
rat LD50 intraperitoneal 260mg/kg (260mg/kg) behavioral: somnolence (general depressed activity) Toxicology and Applied Pharmacology. Vol. 3, Pg. 713, 1961.


  • 1,3-DITERT.BUTYL,2-HYDROXY,5-NITRO-BENZENE 10452-78-5 2,6-Bis(1,1-dimethylethyl)-4-nitrophenol
    2,6-Di-tert-butyl-4-nitrophenol 2,6-bis(tert-butyl)-4-nitrophenol 2,6-di(tert-butyl)-4-Nitrobenzenol, AldrichCPR
    2,6-di(tert-butyl)-4-nitrobenzenol 2,6-di-t-butyl-4-nitrophenol 2,6-ditert-butyl-4-nitro-phenol
    2,6-ditert-butyl-4-nitrophenol 3,5-Di-t-butyl-4-hydroxy-nitrobenzene 4-nitro-2,6-bis-(1,1-dimethylethyl)-phenol
    728-40-5 7L-850 AG-205/01424014
    AI3-25569 AK175953 AKOS005100920
    B-28589 BAY 28589 BBL001771
    BDBM95401 BRN 2056124 Bayer 28,589
    Bayer 28589 Bayer 4889 CAS-728-40-5
    CHEMBL224869 CTK5D6928 DA-41549
    DSSTox_CID_1559 DSSTox_GSID_21559 DSSTox_RID_76210
    DTXSID4021559 EBD2321976 ENT 25,569
    FCGKUUOTWLWJHE-UHFFFAOYSA-N FT-0714407 HMS2620M07
    InChI=1/C14H21NO3/c1-13(2,3)10-7-9(15(17)18)8-11(12(10)16)14(4,5)6/h7-8,16H,1-6H; KS-000000VG LS-104326
    MCULE-3794159716 MLS000755910 NCGC00246556-01
    NCGC00255264-01 NCIOpen2_004262 NSC 81682
    NSC-81682 NSC81682 Oprea1_462619
    Phenol, 2,6-bis(1,1-dimethylethyl)-4-nitro- Phenol, 2,6-bis(1,1-dimethylethyl)-4-nitro- (9CI) Phenol, 2,6-di-t-butyl-4-nitro-
    Phenol, 2,6-di-tert-butyl-4-nitro- Phenol,2,6-bis(1,1-dimethylethyl)-4-nitro- Phenol,6-bis(1,1-dimethylethyl)-4-nitro-
    Phenol,6-di-tert-butyl-4-nitro- Q63441408 SBB100978
    SCHEMBL17411458 SCHEMBL3236587 SMR000337938
    STK331796 T8809 Tox21_301750
    WLN: 1X1&1&R BQ ENW CX1&1&1 ZINC2513362 cid_69765

    CAS Number 10452-78-5, 728-40-5, 7554-16-7
    PubChem Compound 69765