Drug

D0905 | ebselen

Molecular Formula C13H9NOSe
Molecular Weight 274.2
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 23.16±0.93 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 19.45 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 21.42±5.35 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 42 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H301 (97.62%): Toxic if swallowed [Danger Acute toxicity, oral]


H331 (97.62%): Toxic if inhaled [Danger Acute toxicity, inhalation]


H373 (100%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P260, P261, P264, P270, P271, P273, P301+P310, P304+P340, P311, P314, P321, P330, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 1,2-Benzisoselenazol-3(2H)-one, 2-phenyl- 2-Phenyl-1,2-benzisoselenazol-3(2H)-one 2-Phenyl-1,2-benzisoselenazolin-3-one
    2-Phenyl-benzo[d]isoselenazol-3-one 2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen) 2-phenyl-1,2-benzisoselazol-3(2H)-one
    2-phenyl-1,2-benzisoselenazole-3(2H)-one 2-phenyl-1,2-benzoisoselenazol-3(2H)-one 2-phenyl-1,2-benzoisoselenazole-3(2H)-one
    2-phenyl-1,2-benzoisoselenazole-3-(2H)-one 2-phenyl-1,2-benzoselenazol-3(2h)-one 2-phenyl-1,2-benzoselenazol-3-one
    2-phenylbenzo[d][1,2]selenazol-3(2H)-one 40X2P7DPGH 60940-34-3
    940E343 AB00053217 AB00053217_25
    AB0020911 AC-1124 AC1L1FDW
    AK115695 AKOS015898841 API0002512
    AX8127093 BCBcMAP01_000149 BCP17134
    BDBM34233 BN0569 BPBio1_000770
    BRD-K29359156-001-06-1 BRD-K29359156-001-23-6 BSPBio_000700
    BSPBio_001342 BSPBio_002538 Bio2_000062
    Bio2_000542 C042986 C13H9NOSe
    CAS-60940-34-3 CCG-39161 CCRIS 3714
    CHEBI:175507 CHEBI:77543 CHEMBL51085
    CID3194 CPD000058445 CS-5534
    CTK7H1817 DAP001372 DB-072873
    DB12610 DR 3305 DR-3305
    DR3305 DSSTox_CID_25150 DSSTox_GSID_45150
    DSSTox_RID_80704 DTXSID7045150 DYEFUKCXAQOFHX-UHFFFAOYSA-N
    DivK1c_000951 E 3520 E0946
    E3520_SIGMA EU-0100541 EX-A1447
    Ebselen (C5) Ebselen [INN] Ebselen, 99%
    Ebselen, cysteine modifier Ebselene Ebselene [French]
    Ebseleno Ebseleno [Spanish] Ebselenum
    Ebselenum [Latin] FT-0759332 GP4285
    HMS1361D04 HMS1570C22 HMS1791D04
    HMS1989D04 HMS2052N09 HMS2097C22
    HMS2235A11 HMS3394N09 HMS3402D04
    HMS3649O05 HMS3714C22 HMS502P13
    HY-13750 Harmokisane I09-1611
    IDI1_000951 IDI1_033812 KBio1_000951
    KBio2_000062 KBio2_002630 KBio2_005198
    KBio3_000123 KBio3_000124 KBio3_001758
    KBioGR_000062 KBioGR_000830 KBioSS_000062
    KS-00000G4G KSC-325-014 KUC112559N
    LP00541 LS-33527 Lopac-E-3520
    Lopac0_000541 MFCD00210937 MLS-0003066.0001
    MLS000028488 MLS001148646 MLS001424261
    MLS006010108 NC00431 NCGC00015412-01
    NCGC00015412-02 NCGC00015412-03 NCGC00015412-04
    NCGC00015412-05 NCGC00015412-06 NCGC00015412-07
    NCGC00015412-08 NCGC00015412-09 NCGC00015412-10
    NCGC00015412-11 NCGC00015412-12 NCGC00015412-13
    NCGC00024072-03 NCGC00024072-04 NCGC00024072-05
    NCGC00178610-01 NCGC00178610-02 NCGC00178610-03
    NINDS_000951 NSC 639762 NSC-639762
    NSC-757883 NSC639762 NSC757883
    Opera_ID_1643 PZ 51 PZ-51
    PZ51 Pharmakon1600-01501188 Prestwick0_000740
    Prestwick1_000740 Prestwick2_000740 Prestwick3_000740
    Prestwick_1057 Q5332073 QTL1_000035
    RP 60931 SAM001247071 SBI-0050524.P003
    SCHEMBL33829 SMR000058445 SPBio_001301
    SPBio_002639 SPI-1005 SPI-3005
    SR-01000003081 SR-01000003081-10 SR-01000003081-14;
    SR-01000003081-2 SR-01000003081-7 SR-01000003081-8
    Spectrum2_001441 Spectrum3_000799 Spectrum4_000445
    Spectrum5_001713 TRA0091838 Tox21_110140
    UNII-40X2P7DPGH V1941 cid_3194
    ebselen nchembio.109-comp1 phenyl-1,2-benzisoselenazol-3(2H)-one

    DrugBank Name ebselen
    DrugBank DB12610
    CAS Number 172732-68-2, 60940-34-3
    PubChem Compound 3194
    ChEBI 77543