Drug

D1124 | thiram

Molecular Formula C6H12N2S4
Molecular Weight 240.4
Structure

P

P03AA05 Thiram


[P03AA] Sulfur containing products


[P03A] ECTOPARASITICIDES, INCL. SCABICIDES


[P03] ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS


[P] Antiparasitic products, insecticides and repellents


Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 1.94±25.92 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 24.49 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 16.51±20.26 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H315: Causes skin irritation [Warning Skin corrosion/irritation]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H332: Harmful if inhaled [Warning Acute toxicity, inhalation]


H373 **: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P260, P261, P264, P270, P271, P272, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P314, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

Aggregated GHS information provided by 962 companies from 19 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]


H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]


H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]


H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]


H373 (100%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


H400 (98.44%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P260, P261, P264, P270, P271, P272, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P314, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H315: Causes skin irritation [Warning Skin corrosion/irritation]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H332: Harmful if inhaled [Warning Acute toxicity, inhalation]


H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P314, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H330: Fatal if inhaled [Danger Acute toxicity, inhalation]


H340: May cause genetic defects [Danger Germ cell mutagenicity]


H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P314, P320, P321, P330, P333+P313, P337+P313, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H316: Causes mild skin irritation [Warning Skin corrosion/irritation]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H320: Causes eye irritation [Warning Serious eye damage/eye irritation]


H340: May cause genetic defects [Danger Germ cell mutagenicity]


H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P201, P202, P260, P261, P264, P270, P272, P280, P281, P301+P312, P302+P352, P305+P351+P338, P307+P311, P308+P313, P314, P321, P330, P332+P313, P333+P313, P337+P313, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P273, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (dimethylamino){[(dimethylamino)thioxomethyl]disulfanyl}methane-1-thione .alpha.,.alpha.'-Dithiobis(dimethylthio)formamide 0D771IS0FH
    1-(3-{[hydroxy(methoxy)methylidene]amino}phenoxy)-N-(3-methylphenyl)methanimidic acid 1-(dimethylthiocarbamoyldisulfanyl)-N,N-dimethyl-methanethioamide 137-26-8
    26833-EP2280009A1 26833-EP2305658A1 26833-EP2314583A1
    37T268 4-04-00-00242 (Beilstein Handbook Reference) AB00052345_10
    AB1002114 AI3-00987 AKOS000120200
    Aapirol Aatiram Accel TMT
    Accelerant T Accelerator T Accelerator thiuram
    Aceto TETD Agrichem flowable thiram Akrochem TMTD
    Anles Arasan Arasan 42-S
    Arasan 42S Arasan 50 red Arasan 70
    Arasan 70-S Red Arasan 75 Arasan m
    Arasan-M Arasan-SF Arasan-SF-X
    Atiram Attack Attack [Antifungal]
    Aules B0486 BDBM43362
    BIDD:ER0359 BRD-K29254801-001-06-3 BRN 1725821
    BSPBio_003184 Basultra Betoxin
    Bis((dimethylamino)carbonothioyl) disulfide Bis((dimethylamino)carbonothioyl) disulphide Bis(dimethyl thiocarbamoyl)disulfide
    Bis(dimethyl-thiocarbamoyl)-disulfid Bis(dimethyl-thiocarbamoyl)-disulfid [German] Bis(dimethylaminothiocarbonyl)disulfide
    Bis(dimethylthiocarbamoyl) disulfide Bis(dimethylthiocarbamoyl) disulfide Bis(dimethylthiocarbamoyl) disulphide
    Bis(dimethylthiocarbamyl) disulfide Bis(dimethylthiocarbamyl) disulfide Bis[(dimethylamino)carbonothioyl] disulfide
    C-31381 C11160 C6H12N2S4
    CAS-137-26-8 CC-34914 CCG-35460
    CCRIS 1282 CHEBI:9495 CHEMBL120563
    CS-0012858 CTK3J1182 Caswell No. 856
    Chipco thiram 75 Cunitex Cyuram DS
    D06114 DB-042384 DB13245
    DSSTox_CID_1332 DSSTox_GSID_21332 DSSTox_RID_76087
    DTXSID5021332 Delsan Disolfuro di tetrametiltiourame
    Disolfuro di tetrametiltiourame [Italian] Disulfide, bis(dimethylthiocarbamoyl) Disulfure de tetramethylthiourame
    Disulfure de tetramethylthiourame [French] Disulfuro di tetrametiltiourame Disulfuro di tetrametiltiourame [Italian]
    DivK1c_000741 EC 205-286-2 EINECS 205-286-2
    ENT 987 ENT-987 EPA Pesticide Chemical Code 079801
    Ekagom TB F0001-0468 FMC 2070
    FT-0083178 FT-0631799 Falitiram
    Fermide Fermide 850 Fernacol
    Fernasan Fernasan A Fernide
    Flo Pro T Seed Protectant Formalsol Formamide, 1,1'-dithiobis(N,N-dimethylthio-
    Formamide,1'-dithiobis(N,N-dimethylthio- Granuflo HMS1922A12
    HMS2093E03 HMS2234B08 HMS3374C05
    HMS502F03 HSDB 863 Hermal
    Hermat TMT Heryl Hexathir
    Hy-Vic IDI1_000741 InChI=1/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
    J-006992 J-524968 KBio1_000741
    KBio2_002167 KBio2_004735 KBio2_007303
    KBio3_002684 KBioGR_001499 KBioSS_002167
    KS-00000Z7X KS-5354 KSC491C8F
    KUAZQDVKQLNFPE-UHFFFAOYSA- KUAZQDVKQLNFPE-UHFFFAOYSA-N Kregasan
    LS-803 MCULE-4171536161 MFCD00008325
    MLS000069752 MLS002702972 Mercuram
    Methyl Thiram Methyl thiuramdisulfide Methyl tuads
    Methylthiuram disulfide Metiur Metiurac
    Micropearls N(1),N(1),N(3),N(3)-tetramethyl-2-dithioperoxy-1,3-dithiodicarbonic diamide N,N',N'-Tetramethylthiuram disulfide
    N,N'-(Dithiodicarbonothioyl)bis(N-methylmethanamine) N,N,N',N'-Tetramethylthiuram disulfide N,N-Tetramethylthiuram disulfide
    N,N-Tetramethylthiuram disulphide N,N-dimethyl[(dimethylcarbamothioyl)disulfanyl]carbothioamide N,N-dimethylcarbamodithioic acid (dimethylthiocarbamoylthio) ester
    N,N-dimethylcarbamodithioic acid [[dimethylamino(sulfanylidene)methyl]thio] ester; NCGC00091563-01 NCGC00091563-02
    NCGC00091563-03 NCGC00091563-04 NCGC00091563-05
    NCGC00091563-06 NCGC00091563-07 NCGC00091563-08
    NCGC00091563-09 NCGC00091563-10 NCGC00091563-12
    NCGC00255002-01 NCGC00259118-01 NCI60_001477
    NCI60_006736 NCIMech_000272 NCIOpen2_007854
    NINDS_000741 NSC 1771 NSC 49512
    NSC 59637 NSC 622696 NSC-1771
    NSC-49512 NSC-622696 NSC-758454
    NSC1771 NSC49512 NSC59637
    NSC622696 NSC758454 Naftocit thiuram 16
    Nobecutan Nocceler TT Nomersan
    Normersan Orac TMTD Panoram 75
    Perkacit TMTD Pharmakon1600-01503322 Pol-Thiuram
    Polyram ultra Pomarsol Pomarsol forte
    Pomasol Puralin Q416572
    QTL1_000082 RCRA waste no. U244 RCRA waste number U244
    RTR-004967 Radothiram Rezifilm
    Rezifilm (TN) Robac TMT Royal TMTD
    SBB000804 SBI-0051813.P002 SC-18941
    SCHEMBL21144 SMR000059023 SPBio_001428
    SPECTRUM1503322 SQ 1489 SQ-1489
    SR-01000736911 SR-01000736911-2 ST044501
    STL264104 Sadoplon Sadoplon 75
    Spectrum2_001554 Spectrum3_001592 Spectrum4_000860
    Spectrum5_001653 Spectrum_001687 Spotrete
    Spotrete WP 75 Spotrete-F Sranan-sf-X
    TETRAMETHYLTHIOPEROXYDICARBONIC ACID [(H2N)C(S)]2S2 TMT Disulfide TMTD
    TMTDS TNTD TR-004967
    TRA-0180716 TUEX Teramethylthiuram disulfide
    Tersan Tersan 75 Tersantetramethyldiurane sulfide
    Tetramethyl thiuram disulfide Tetramethyl thiuramdisulfide Tetramethyl thiurane disulfide
    Tetramethyl thiurane disulphide Tetramethyl-thiram disulfid Tetramethyl-thiram disulfid [German]
    Tetramethyldiurane sulphite Tetramethylenethiuram disulfide Tetramethylenethiuram disulphide
    Tetramethylthiocarbamoyldisulphide Tetramethylthioperoxydicarbonic diamide Tetramethylthioramdisulfide
    Tetramethylthioramdisulfide [Dutch] Tetramethylthiouram disulfide Tetramethylthiuram
    Tetramethylthiuram bisulfide Tetramethylthiuram bisulphide Tetramethylthiuram disulfide
    Tetramethylthiuram disulfide, 97% Tetramethylthiuram disulphide Tetramethylthiuran disulphide
    Tetramethylthiurane disulfide Tetramethylthiurum disulfide Tetramethylthiurum disulphide
    Tetrapom Tetrasipton Tetrathiuram disulfide
    Tetrathiuram disulphide Thianosan Thillate
    Thimar Thimer Thioknock
    Thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N',N'-tetramethyl- Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetramethyl- Thioperoxydicarbonic diamide ((H2N)C(S))2S2, tetramethyl-
    Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N,N',N'-tetramethyl- Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), tetramethyl- Thioperoxydicarbonic diamide, tetramethyl-
    Thiosan Thioscabin Thiotex
    Thiotox Thiotox (fungicide) Thiram
    Thiram (Tmtd) Thiram (USAN/INN) Thiram 10 microg/mL in Cyclohexane
    Thiram 75 Thiram 80 Thiram B
    Thiram [BSI:ISO] Thiram [USAN:INN:BSI:ISO] Thiram [USAN:INN]
    Thiram, PESTANAL(R), analytical standard Thiram, certified reference material, TraceCERT(R) Thiramad
    Thirame Thirame [INN-French] Thirampa
    Thiramum Thiramum [INN-Latin] Thirasan
    Thiulin Thiulix Thiurad
    Thiuram Thiuram D Thiuram M
    Thiuram M rubber accelerator Thiuram disulfide, tetramethyl- Thiuram-M
    Thiuramin Thiuramyl Thylate
    Tiradin Tirampa Tiuramyl
    Tox21_111150 Tox21_111150_1 Tox21_201569
    Tox21_301102 Trametan Tridipam
    Tripomol Tuads Tutan
    Tyradin UNII-0D771IS0FH VUAgT-I-4
    Vancida tm-95 Vancide TM Vancide TM-95
    Vanguard GF Vulcafor TMT Vulcafor TMTD
    Vulkacit DTMT Vulkacit TH Vulkacit mtic
    Vulkacit thiuram Vulkazam S WLN: 1N1 & YUS & SSYUS & N1 & 1
    ZINC1532176 Zaprawa Nasienna T [Me2NC(S)S]2
    [disulfanediylbis(carbonothioylnitrilo)]tetramethane [dithiobis(carbonothioylnitrilo)]tetramethane alpha,alpha'-Dithiobis(dimethylthio)formamide
    bis (dimethyl thiocarbamoyl) disulfide bmse000928 cid_5455
    dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate thiram tiramo

    DrugBank DB13245
    CAS Number 137-26-8, 69193-86-8, 991-20-8
    PubChem Compound 5455
    KEGG Compound ID C11160
    KEGG Drug D06114
    ChEBI 9495