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Compound

D1006 | montelukast sodium

Molecular Formula C35H35ClNNaO3S
Molecular Weight 608.2
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 32.71±1.32 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL human HepG2 MMP assay Negative IC50 163
MEMBRANE POTENTIAL 24.08±9.54 rat hepatocytes MMP assay decrease IC50 163


  • 1-((((1R)-1-(3-((1E)-2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid monosodium salt 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt 1-[[[(R)-1-[3-[2-(7-Chloro-2-quinolyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-1-cyclopropaneacetic acid sodium salt
    142522-81-4 151767-02-1 176636-EP2287154A1
    2-[1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]thio]methyl]cyclopropyl]acetate ACN-052465 ACT06295
    AKOS015833416 AKOS032949734 AM62787
    AMX10104 AOB6098 BCP9000959
    C35H35ClNO3S.Na CAS-151767-02-1 CCG-101049
    CHEBI:6993 CHEMBL1200681 CM0155
    CPD000469188 CS-0548 CYC099
    Cyclopropaneacetic acid, 1-((((1R)-1-(3-((1E)-2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)-, monosodium salt Cyclopropaneacetic acid, 1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)-, sodium salt, (R-(E))- Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-, sodium salt (1:1)
    Cyclopropaneacetic acid,1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-,sodium salt D00529 DSSTox_CID_26450
    DSSTox_GSID_46450 DSSTox_RID_81624 DTXSID60931503
    DTXSID8046450 FT-0082752 HMS2051F18
    HMS2235H19 HY-13315 J-008841
    J-522711 KS-1087 Kipres
    Kokast L-706631 LBFBRXGCXUHRJY-HKHDRNBDSA-M
    LS-173407 Lukasm M2340
    MK 0476 MK 476 MK-0476
    MK-476 MLS001304727 MLS001424198
    MONTELUKAST Na MONTELUKAST SODIUM Montair
    Montelukast (sodium) Montelukast monosodium salt Montelukast sodium (JP17/USAN)
    Montelukast sodium [USAN] Montelukast sodium salt Montelukast sodium, 98%
    NC00299 NCGC00164568-01 NCGC00164568-04
    Q27107384 SAM001246657 SCHEMBL9414
    SCHEMBL9415 SMR000469188 SW197679-2
    Singulair Singulair (TN) Singular
    Sodium (1-{[(1-{3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl)sulfanyl]methyl}cyclopropyl)acetate Sodium 1-((((R)-m -((E)-2-(7-chloro-2-quinolyl)vinyl)-alpha-(o-(1-hydroxy-1-methylethyl)phenethyl)benzyl)thio)methyl)cyclopropaneacetate Sodium 1-((((R)-m-((E)-2-(7-chloro-2-quinolyl)vinyl)-alpha-(o-(1-hydroxy-1-methylethyl)phenethyl)benzyl)thio)methyl)cyclopropaneacetate
    Tox21_112197 Tox21_112197_1 U1O3J18SFL
    UNII-U1O3J18SFL montelukast-sodium s4211
    sodium sodium (R,E)-2-(1-((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylthio)methyl)cyclopropyl)acetate sodium 1-[[[(1R)-1-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetate
    sodium 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl)acetate; sodium {1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetate sodium;2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate

    CAS Number 151767-02-1
    PubChem Compound 23663996
    KEGG Drug D00529
    ChEBI 6993