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Compound

D0836 | carminomycin

Molecular Formula C26H27NO10
Molecular Weight 513.5
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 1.25±0.73 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 21.82 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 oral 7250ug/kg (7.25mg/kg) Antibiotiki. Vol. 28, Pg. 90, 1983.
mouse LD50 intraperitoneal 1100ug/kg (1.1mg/kg) Antibiotiki. Vol. 29, Pg. 666, 1984.
mouse LD50 intravenous 3400ug/kg (3.4mg/kg) Antibiotiki. Vol. 28, Pg. 90, 1983.
mouse LD50 subcutaneous 3800ug/kg (3.8mg/kg) Antibiotiki. Vol. 19, Pg. 57, 1974.


  • (1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,10,12-tetrahydroxy-6,11-dioxo-1-naphthacenyl-3-amino-2,3,6-tridesoxy-alpha-L-lyxo-hexopyranosid (1S,3S)-3-acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione
    39472-31-6 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S-cis)- 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S,10S)-
    50935-04-1 935C041 B5825
    BDBM50103635 C12432 C26H27NO10
    CAS-50935-04-1 CCRIS 6185 CCRIS 961
    CHEBI:31359 CHEMBL474260 Carminomicin I
    Carminomycin Carminomycin Carminomycin I
    Carminomycin I|||(8S,10S)-8-acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,6,8,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Carminomycin, O-Demethyldaunomycin, CCRIS 961 Carubicin
    Carubicin Carubicin [INN] Carubicina
    Carubicina [INN-Spanish] Carubicine Carubicine [INN-French]
    Carubicinum Carubicinum [INN-Latin] DSSTox_CID_2742
    DSSTox_GSID_22742 DSSTox_RID_76711 DTXSID3022742
    E7437K3983 EX-A2244 FT-0664386
    KARMINOMYCIN Karminomitsin MCULE-8337547015
    NCGC00159344-02 NCGC00160675-01 NSC-180024
    O-Demethyldaunomycin Q5047474 SCHEMBL9552
    Tox21_111589 Tox21_111978 UNII-E7437K3983
    V1723 ZINC4654755

    CAS Number 39472-31-6, 50935-04-1
    PubChem Compound 443831
    KEGG Compound ID C12432
    ChEBI 31359