Drug

D0479 | ethynodiol diacetate

Molecular Formula C24H32O4
Molecular Weight 384.5
Structure
State solid
Protein binding 50-85%

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 15.40±0.84 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 21.82 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163
ELECTRON TRANSPORT CHAIN rat isolated liver mitochondria measurements of mitochondrial respiration; RST inhibition assay, RST uncoupling assay; IC 50ratio of glucose/galactose assay decrease 53

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 57 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H302 (96.49%): Harmful if swallowed [Warning Acute toxicity, oral]


H312 (96.49%): Harmful in contact with skin [Warning Acute toxicity, dermal]


H332 (96.49%): Harmful if inhaled [Warning Acute toxicity, inhalation]


H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]


H360 (29.82%): May damage fertility or the unborn child [Danger Reproductive toxicity]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P312, P322, P330, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (3 beta, 17 alpha)-19-Norpregn-4-en-20-yne-3,17 diol Diacetate (3-beta,17-alpha)-19-Norpregn-4-en-20-yne-3,17-diol diacetate (3S,8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl diacetate
    (3beta,17alpha)-19-Norpregn-4-en-20-yne-3,17-diyl diacetate (3beta,17beta)-17-ethynylestr-4-ene-3,17-diyl diacetate 17-alpha-Ethynyl-19-norandrost-4-ene-3-beta,17-beta-diol diacetate
    17-alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetate 17-alpha-Ethynyl-4-estrene-3-beta,17-beta-diol diacetate 17-alpha-Ethynylestr-4-ene-3-beta,17-beta-diol acetate
    17a-Ethynyl-4-estren-3b,17-diol diacetate 17alpha-Ethynyl-19-norandrost-4-ene-3beta,17-beta-diol diacetate 17alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetate
    17alpha-Ethynyl-4-estrene-3beta,17beta-diol diacetate 17alpha-Ethynylestr-4-ene-3beta,17beta-diol acetate 17alpha-ethynylestr-4-ene-3beta,17beta-diyl diacetate
    19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol diacetate 19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol, diacetate 19-Nor-17alpha-pregn-4-en-20-yne-3beta,17-diol diacetate
    19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3b,17a)- 19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3beta,17alpha)- 19-norpregn-4-en-20-yn-3beta,17alpha-diol, diacetate
    297-76-7 297E767 3-beta, 17-beta-Diacetoxy-17-alpha-ethynyl-4-oestrene
    3-beta,17-beta-Diacetoxy-19-nor-17-alpha-pregn-4-en-20-yne 3beta, 17beta-Diacetoxy-17alpha-ethynyl-4-oestrene 3beta,17beta-Diacetoxy-19-nor-17alpha-pregn-4-en-20-yne
    62H10A1236 8080 C. B 8080 C. B.
    8080 CB A820050 AB00513958
    AB00513958_02 AK129080 AKOS015895252
    AS-13382 B1508 BCP10923
    BDBM50237627 BPBio1_000832 BSPBio_000756
    C-21409 C12724 CAS-297-76-7
    CC-28314 CCG-220908 CCRIS 305
    CHEBI:31580 CHEMBL1200624 CS-4640
    Cervicundin Continuin D01294
    DB00823 DSSTox_CID_614 DSSTox_GSID_20614
    DSSTox_RID_75690 DTXSID4020614 EBD2209572
    EINECS 206-044-9 ETHYNODIOL DIACETATE Ethinodiol diacetate
    Ethynodiol (diacetate) Ethynodiol acetate Ethynodiol diacetate (JAN/USP)
    Ethynodiol diacetate [Progestins] Ethynodiol diacetate [USAN:USP] Ethynodiol diacetate [USAN]
    Ethynodiol diacetate, United States Pharmacopeia (USP) Reference Standard Etynodiol Acetate Etynodiol di(acetate)
    Etynodiol diacetate Femulen GTPL7072
    HMS1570F18 HMS2097F18 HMS3714F18
    HY-B1089 I036 J-017631
    LMST02030124 LS-7392 Luto-metrodiol
    MLS000028661 Metrodiol Metrodiol diacetate
    NCGC00166138-01 NCGC00166138-02 NCGC00166138-04
    NCGC00166138-05 NCGC00186466-01 ONKUMRGIYFNPJW-KIEAKMPYSA-N
    Ovulen 50 Prestwick0_000908 Prestwick1_000908
    Prestwick2_000908 Prestwick3_000908 Q5405160
    SC 11800 SC-11800 SCHEMBL40888
    SMR000058858 SPBio_002955 SR-01000872687
    SR-01000872687-1 Tox21_112333 Tox21_112333_1
    Tox21_112924 UNII-62H10A1236 ZINC3876023
    [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ethanoate acetic acid [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester;
    ethynodiol-diacetate s3160

    DrugBank Name ethynodiol diacetate
    DrugBank DB00823
    CAS Number 297-76-7, 8056-92-6
    PubChem Compound 9270
    KEGG Compound ID C12724
    KEGG Drug D01294
    ChEBI 31580