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2021 MitoTox | (CC BY-NC 4.0)
Compound

D1004 | mk-2206

Molecular Formula C25H21N5O
Molecular Weight 407.5
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 17.78±7.38 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 17.34 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163


  • 1,2,4-Triazolo(3,4-f)(1,6)naphthyridin-3(2H)-one, 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl- 1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-;1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl- 1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-;1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-;8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-ol
    1032349-93-1 51HZG6MP1K 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthy ridin-3(2H)-one
    8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f]-1,6-naphthyridin-3(2H)-one; 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one
    8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one AKOS032945686
    API0006847 BCP20200 BCP9000938
    BDBM50313650 BRD-K68065987-300-02-6 CAS-1032350-13-2
    CHEBI:67271 CHEMBL1079175 DB-058959
    DSSTox_CID_28874 DSSTox_GSID_48948 DSSTox_RID_83143
    DTXSID3048948 FT-0738942 GTPL7945
    MK 2206;MK2206 MK-2206 MK-2206 free base
    MK2206;MK 2206;MK-2206 dihydrochloride NCGC00186465-01 NCGC00186465-02
    NCGC00186465-03 NCGC00186465-04 NCGC00186465-08
    Q25100065 SB16805 SCHEMBL530721
    Tox21_113368 Tox21_113368_1 ULDXWLCXEDXJGE-UHFFFAOYSA-N
    UNII-51HZG6MP1K Z-3283 ZINC36382821
    cas:1032350-13-2;MK 2206

    CAS Number 1032349-77-1, 1032349-93-1, 1032350-13-2
    PubChem Compound 24964624
    ChEBI 67271