D0624 | 2-(thiocyanomethylthio)benzothiazole
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 33.08±4.58 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 56.23 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 30.47±26.36 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
   |
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H315: Causes skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P320, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
Aggregated GHS information provided by 338 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H330 (100%): Fatal if inhaled [Danger Acute toxicity, inhalation] H400 (96.15%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P320, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H315: Causes skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P320, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Danger |
H227: Combustible liquid [Warning Flammable liquids] H302: Harmful if swallowed [Warning Acute toxicity, oral] H315: Causes skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P201, P202, P210, P260, P261, P264, P270, P271, P272, P280, P281, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P310, P314, P320, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Danger |
H227: Combustible liquid [Warning Flammable liquids] H302: Harmful if swallowed [Warning Acute toxicity, oral] H315: Causes skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H351: Suspected of causing cancer [Warning Carcinogenicity] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P210, P260, P261, P264, P270, P271, P272, P273, P280, P281, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P310, P320, P321, P330, P332+P313, P333+P313, P362, P363, P370+P378, P391, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LC50 | inhalation | > 170mg/m3 (170mg/m3) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| rat | LD50 | subcutaneous | 1300mg/kg (1300mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| mouse | LD50 | intraperitoneal | 143mg/kg (143mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| rat | LD50 | intraperitoneal | 73mg/kg (73mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| rat | LD50 | oral | 2538mg/kg (2538mg/kg) | Buckman Laboratories, Inc. Vol. 14FEB1980, | |
| rabbit | LD50 | skin | 10gm/kg (10000mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| rabbit | LD50 | skin | 642mg/kg (642mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| rat | LD50 | skin | > 5gm/kg (5000mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| duck | LD50 | oral | 1310mg/kg (1310mg/kg) | Buckman Laboratories, Inc. Vol. TCMTB, Pg. 1981, | |
| mouse | LD50 | oral | 445mg/kg (445mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| rat | LD50 | oral | 2gm/kg (2000mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| rat | LD50 | oral | 679mg/kg (679mg/kg) | Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 207, 1992. | |
| rat | LD50 | oral | 1590mg/kg (1590mg/kg) | Buckman Laboratories, Inc. Vol. TCMTB, Pg. 1981, | |
| rabbit | LD50 | skin | 200mg/kg (200mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| rabbit | LD50 | skin | 10gm/kg (10000mg/kg) | Buckman Laboratories, Inc. Vol. 14FEB1980, | |
| mouse | LD50 | subcutaneous | 205mg/kg (205mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 12, Pg. 343, 1987. | |
| (1,3-Benzothiazol-2-ylsulfanyl)methyl thiocyanate # | (1,3-Benzothiazol-2-ylsulfanyl)methyl thiocyanate (2-benzothiazolylthio)methylthiocyanate[qr]; | (1,3-benzothiazol-2-ylthio)methyl thiocyanate |
| (2-Benzothiazolylthio)methyl thiocyanate | (Benzothiazol-2-ylthio)methyl thiocyanate | 1,3-benzothiazol-2-ylsulfanylmethyl thiocyanate |
| 2-((Thiocyanatomethyl)thio)benzo[d]thiazole | 2-((Thiocyanatomethyl)thio)benzothiazole | 2-(4-Thiocyanomethythio)Benzothiazole |
| 2-(Benzothiazolylthio)methyl thiocyanate | 2-(Thiocyanatomethylthio)benzo[d]thiazole | 2-(Thiocyanatomethylthio)benzothiazole |
| 2-(Thiocyanatomethylthio)benzothiazole, PESTANAL(R), analytical standard | 2-(Thiocyanomethylthio)benzothiazole | 2-(Thiocyanomethylthio)benzothiazole, 60% |
| 2-Benzothiazolylthio methyl thiocyanate | 2-Thiocyanomethylthiobenzothiazole, 80% | 2-Tiocianometiltiobenzotiazolo |
| 2-Tiocianometiltiobenzotiazolo [Italian] | 2-Tiocianometiltiobenzotiazolo, 80% | 2-Tiocianometiltiobenzotiazolo, 80% [Italian] |
| 2-[(Thiocyanatomethyl)thio]benzothiazole | 21564-17-0 | 564T170 |
| 5GE166YVQV | A815476 | ACM21564170 |
| AI3-29396-X (USDA) | AKOS015915374 | AM84757 |
| AX8019384 | Acticide WB 300 | Alentisan |
| BCP25511 | BRN 1213014 | Benthiazole |
| Benthiazole 30% | Benzothiazole, 2-((thiocyanatomethyl)thio)- | Benzothiazole, 2-((thiocyanatomethyl)thio)- (8CI) |
| Busan | Busan 1030 | Busan 15 |
| Busan 30 | Busan 30-1 | Busan 30A |
| Busan 30I | Busan 44 | Busan 70 |
| Busan 71 | Busan 72 | Busan 72A |
| C-36790 | C9H6N2S3 | CAS-21564-17-0 |
| CHEMBL1903976 | CTK1A2536 | Caswell No. 853A |
| DB-030386 | DSSTox_CID_12647 | DSSTox_GSID_32647 |
| DSSTox_RID_79023 | DTXSID6032647 | Delsan 30 |
| EINECS 244-445-0 | EPA Pesticide Chemical Code 035603 | FCH1329754 |
| FT-0638130 | HSDB 6450 | Ichiban |
| J-014149 | KS-00000ZR0 | KVK 733059 |
| LS-152632 | NCGC00168337-01 | NCGC00168337-02 |
| NCGC00254973-01 | P282 | Protector 3L |
| PubChem23353 | Q158532 | SC-47242 |
| SCHEMBL54175 | ST24039028 | Sancelant TMB |
| Superdavloxan | TCMTB | TCMTB (2-(Thiocyanomethylthio)benzothiazole) |
| TCMTB (Busan) | TCMTB 100 microg/mL in Acetonitrile | TCMTB 30% |
| TCMTB 60% | TCMTB 80% | THIOCYANIC ACID, (2-BENZOTHIAZOLYLTHIO)METHYL ESTER |
| TUBQDCKAWGHZPF-UHFFFAOYSA-N | Thiocyanic acid, (2-benzothiazolylthio) methyl ester | Thiocyanic acid, (2-benzothiazolylthio)methyl ester, 30% |
| Thiocyanic acid, 2-(benzothiazolylthio)methyl ester, 60% | Thiocyanic acid, 2-(benzothiazolylthio)methyl ester, 80% | Tolcide 2230 |
| Tox21_301072 | UNII-5GE166YVQV | ZINC2016149 |
| thiocyanic acid (1,3-benzothiazol-2-ylthio)methyl ester |
| CAS Number | 21564-17-0 |
| PubChem Compound | 30692 |