Compound
D0602 | 1-amino-2,4-dibromoanthraquinone
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 2.78±3.75 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | human | HepG2 | MMP assay | Negative | IC50 | 163 | ||
| MEMBRANE POTENTIAL | 27.37±4.44 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
  |
Warning |
Aggregated GHS information provided by 44 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H319 (90.91%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H351 (13.64%): Suspected of causing cancer [Warning Carcinogenicity] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P264, P280, P281, P305+P351+P338, P308+P313, P337+P313, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H350: May cause cancer [Danger Carcinogenicity] |
P201, P202, P281, P308+P313, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 8900ug/kg (8.9mg/kg) | Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 3, Pg. 101, 1982. | |
| mouse | LD50 | intraperitoneal | 9200ug/kg (9.2mg/kg) | Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 3, Pg. 101, 1982. | |
| mouse | LD50 | oral | 293mg/kg (293mg/kg) | Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 3, Pg. 101, 1982. | |
| 1-AMINO-2,4-DIBROMOANTHRA-QUINONE | 1-AMINO-2,4-DIBROMOANTHRAQUINONE | 1-Amino-2, 4-dibromoanthraquinone |
| 1-Amino-2,4-dibromanthrachinon | 1-Amino-2,4-dibromanthrachinon [Czech] | 1-Amino-2,4-dibromoanthra-9,10-quinone |
| 1-amino-2,4-dibromo-9,10-Anthracenedione | 1-amino-2,4-dibromo-9,10-anthraquinone | 1-amino-2,4-dibromo-9,10-dihydroanthracene-9,10-dione; |
| 1-amino-2,4-dibromoanthracene-9,10-dione | 2,4-Dibromo-1-anthraquinonylamine | 4-14-00-00444 (Beilstein Handbook Reference) |
| 81-49-2 | 9, 1-amino-2,4-dibromo- | 9,10-Anthracenedione, 1-amino-2,4-dibromo- |
| AC-13906 | AE-641/00127034 | AI3-16445 |
| AKOS000668885 | AS-61164 | Anthraquinone, 1-amino-2,4-dibromo- |
| Anthraquinone,4-dibromo- | BBL013158 | BRN 1993373 |
| C-58057 | C14H7Br2NO2 | C19211 |
| CAS-81-49-2 | CCRIS 5884 | CHEBI:82304 |
| CHEMBL559749 | CTK8E3193 | DB-056532 |
| DSSTox_CID_52 | DSSTox_GSID_39235 | DSSTox_RID_79429 |
| DTXSID4039235 | Dibromoaminoanthraquinone | Dibromoaminoanthraquinone (Related) |
| EINECS 201-354-0 | FT-0607312 | HSDB 5241 |
| LS-74 | MCULE-1430116078 | MFCD00019155 |
| NCGC00260131-01 | NCI-C55458 | NSC 3529 |
| NSC-3529 | NSC3529 | Q27155867 |
| RF75O3IKOZ | SCHEMBL3272427 | ST50409824 |
| STK803590 | TR-031304 | Tox21_202582 |
| U138 | UNII-RF75O3IKOZ | W-104207 |
| WLN: L C666 BV IVJ DZ EE GE | ZINC3873982 | ZINRVIQBCHAZMM-UHFFFAOYSA-N |
| l-amino-2,4-dibromoanthraquinone |