Compound

D0939 | flunixin meglumine

Molecular Formula C21H28F3N3O7
Molecular Weight 491.5
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 9.02±0.00 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 7.4 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 5.77±4.59 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 206 companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


Reported as not meeting GHS hazard criteria by 1 of 206 companies. For more detailed information, please visit ECHA C&L website


Of the 15 notification(s) provided by 205 of 206 companies with hazard statement code(s):


H301 (79.51%): Toxic if swallowed [Danger Acute toxicity, oral]


H315 (19.51%): Causes skin irritation [Warning Skin corrosion/irritation]


H318 (35.12%): Causes serious eye damage [Danger Serious eye damage/eye irritation]


H319 (63.41%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H330 (77.07%): Fatal if inhaled [Danger Acute toxicity, inhalation]


H335 (55.12%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


H372 (24.39%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


H411 (77.56%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P260, P261, P264, P270, P271, P273, P280, P284, P301+P310, P302+P352, P304+P340, P305+P351+P338, P310, P312, P314, P320, P321, P330, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol 2-(2-methyl-3-(trifluoromethyl)phenylamino)nicotinate (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol;2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid 1-Deoxy-1-(methylamino)-D-glucitol 2-(2-methyl-3-(perfluoromethyl)anilino)nicotinate
    1-deoxy-1-(methylazaniumyl)-D-glucitol 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinate 2-((2-Methyl-3-(trifluoromethyl)-phenyl)amino)-3-pyridinecarboxylic acid with meglumine compounded 2-((2-methyl-3-(trifluoromethyl)- phenyl)amino)-3-pyridinecarboxylic acid with meglumine compounded
    2-(alpha(sup 3),alpha(sup 3),alpha(sup 3)-Trifluoro-2,3-xylidino)nicotinic acid compound with 1-deoxy-1-(methylamino)-D-glucitol (1:1) 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid--1-deoxy-1-(methylamino)-D-glucitol (1/1);
    3-Pyridinecarboxylic acid, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:1) 42461-84-7 461F847
    8Y3JK0JW3U AB00920714_05 AB00920714_06
    AB2000512 AC-6012 AKOS015895954
    API0025954 BSPBio_002558 Banamine
    Banamine (Veterinary) Banamine [vetarynary] (TN) C-22876
    C14H11F3N2O2.C7H17NO5 C21H28F3N3O7 CCG-213338
    CHEBI:76144 CHEMBL1733447 CS-2460
    CTK8F9789 Certified Reference Material D-Glucitol, 1-deoxy-1-(methylamino)-, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxylate (salt)
    D04216 EINECS 255-836-0 FLUNIXIN MEGLUMINE
    FT-0626443 Flumeglumine Flunixin (meglumine)
    Flunixin Meglumine [USAN] Flunixin Meglumine, Pharmaceutical Secondary Standard Flunixin N-methylglucanine
    Flunixin meglumin Flunixin meglumine (USP) Flunixin meglumine [USAN:USP]
    Flunixin meglumine, >=98% (HPLC) Flunixin meglumine, European Pharmacopoeia (EP) Reference Standard Flunixin meglumine, United States Pharmacopeia (USP) Reference Standard
    Flunixin-S HMS2093I10 HMS2234K05
    HY-B0386 K-8817 KS-000010G2
    KS-5126 LS-71360 MGCCHNLNRBULBU-WZTVWXICSA-N
    MLS001333159 MLS002153985 NCGC00180889-01
    NSC-759583 NSC759583 Pharmakon1600-01505113
    PubChem15394 Q-201124 Q27145782
    SC-18614 SCHEMBL43691 SMR000875279
    SPECTRUM1505113 SR-05000001901 SR-05000001901-1
    SR-05000001901-3 SW196448-3 Sch 14714 meglumine
    Sch-14714 meglumine UNII-8Y3JK0JW3U finadyne
    flunixin-meglumin s2108

    CAS Number 42461-84-7
    PubChem Compound 39212
    KEGG Drug D04216
    ChEBI 76144