D1150 | triphenyltin acetate
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 0.12±0.04 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 1.12 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 24.13±10.14 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
     |
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H315: Causes skin irritation [Warning Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H351: Suspected of causing cancer [Warning Carcinogenicity] H361d ***: Suspected of damaging the unborn child [Warning Reproductive toxicity] H372 **: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P261, P264, P270, P271, P273, P280, P281, P284, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P310, P312, P314, P320, P321, P322, P330, P332+P313, P361, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
Aggregated GHS information provided by 196 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301+H311 (19.39%): Toxic if swallowed or in contact with skin [Danger Acute toxicity, oral acute toxicity, dermal] H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] H311 (100%): Toxic in contact with skin [Danger Acute toxicity, dermal] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H330 (100%): Fatal if inhaled [Danger Acute toxicity, inhalation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H351 (100%): Suspected of causing cancer [Warning Carcinogenicity] H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H371 (19.39%): May cause damage to organs [Warning Specific target organ toxicity, single exposure] H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P261, P264, P270, P271, P273, P280, P281, P284, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P309+P311, P310, P312, P314, P320, P321, P322, P330, P332+P313, P361, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H315: Causes skin irritation [Warning Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H351: Suspected of causing cancer [Warning Carcinogenicity] H361d: Suspected of damaging the unborn child [Warning Reproductive toxicity] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P261, P264, P270, P271, P273, P280, P281, P284, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P310, P312, P314, P320, P321, P322, P330, P332+P313, P361, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P284, P301+P310, P302+P352, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P320, P321, P322, P330, P333+P313, P361, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P284, P301+P310, P302+P352, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P320, P321, P322, P330, P333+P313, P361, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| bird - wild | LD50 | oral | 100mg/kg (100mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |
| guinea pig | LDLo | skin | 180mg/kg (180mg/kg) | British Journal of Industrial Medicine. Vol. 23, Pg. 222, 1966. | |
| guinea pig | LD50 | intraperitoneal | 3740ug/kg (3.74mg/kg) | British Journal of Industrial Medicine. Vol. 23, Pg. 222, 1966. | |
| rat | LD50 | oral | 125mg/kg (125mg/kg) | Tin and Its Uses. Vol. 43, Pg. 9, 1958. | |
| guinea pig | LD50 | oral | 21mg/kg (21mg/kg) | "Pflanzenschutz-und Schaedlingsbekaempfungsmittel: Abriss einer Toxikologie und Therapie von Vergiftungen," 2nd ed., Klimmer, O.R., Hattingen, Fed. Rep. Ger., Hundt-Verlag, 1971Vol. -, Pg. 127, 1971. | |
| mouse | LD50 | intraperitoneal | 7900ug/kg (7.9mg/kg) | behavioral: somnolence (general depressed activity) | British Journal of Industrial Medicine. Vol. 23, Pg. 222, 1966. |
| mouse | LD50 | intravenous | 18mg/kg (18mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00648, | |
| rabbit | LD50 | oral | 30mg/kg (30mg/kg) | "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976. | |
| mouse | LD50 | oral | 81mg/kg (81mg/kg) | behavioral: somnolence (general depressed activity) | British Journal of Industrial Medicine. Vol. 23, Pg. 222, 1966. |
| rat | LD50 | skin | 450mg/kg (450mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 934, 1969. | |
| quail | LD50 | oral | 100mg/kg (100mg/kg) | Journal of Reproduction and Fertility. Vol. 48, Pg. 371, 1976. | |
| rat | LD50 | intraperitoneal | 8500ug/kg (8.5mg/kg) | behavioral: somnolence (general depressed activity) | British Journal of Industrial Medicine. Vol. 23, Pg. 222, 1966. |
| rat | LD50 | intravenous | 18mg/kg (18mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 281, 1973. | |
| chicken | LDLo | intraperitoneal | 40mg/kg (40mg/kg) | British Journal of Industrial Medicine. Vol. 23, Pg. 222, 1966. | |
| mouse | LD50 | subcutaneous | 44mg/kg (44mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 281, 1973. | |
| rabbit | LD50 | intraperitoneal | 10mg/kg (10mg/kg) | lungs, thorax, or respiration: dyspnea | Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 432, 1963. |
| chicken | LD | oral | > 300mg/kg (300mg/kg) | British Journal of Industrial Medicine. Vol. 23, Pg. 222, 1966. | |
| (Acetyloxy)(triphenyl)stannane | (Acetyloxy)(triphenyl)stannane # | (Acetyloxy)triphenylstannane |
| (acetyloxy)triphenyl-Stannane | 900-45-8 | 900-95-8 |
| AI3-25208 | AKOS015902800 | Acetate de triphenyl-etain |
| Acetate de triphenyl-etain [French] | Acetato di stagno trifenile | Acetato di stagno trifenile [Italian] |
| Acetatotriphenylstannane | Acetic acid, triphenylstannyl ester | Acetoxy-triphenyl-stannan |
| Acetoxy-triphenyl-stannan (german) | Acetoxy-triphenyl-stannan [German] | Acetoxy-triphenylstannane |
| Acetoxytriphenyl-Stannane | Acetoxytriphenyl-Tin | Acetoxytriphenylstannane |
| Acetoxytriphenyltin | BRN 4146107 | Batasan |
| Benzaldehyde, m-nitro-, 3-thio-4-o-tolylsemicarbazone | Brestan | Brestan 60 |
| C18728 | CAS-900-95-8 | CCRIS 8605 |
| CHEBI:81918 | Caswell No. 896C | DB-057182 |
| DSSTox_CID_1408 | DSSTox_GSID_21408 | DSSTox_RID_76144 |
| DTXSID6021408 | EINECS 212-984-0 | ENT 25208 |
| EPA Pesticide Chemical Code 496700 | FT-0603522 | Fenolovo acetate |
| Fentin acetaat | Fentin acetaat [Dutch] | Fentin acetat |
| Fentin acetat (german) | Fentin acetat [German] | Fentin acetate |
| Fentin acetate [BSI:ISO] | Fentin acetate [BSI] | Fentin acetate, PESTANAL(R), analytical standard |
| Fentin azetat | Fentin azetat [German] | Fentin-acetate |
| Fentinacetat | Fentine acetate | Fentine acetate [French] |
| Fintin acetato | Fintin acetato [Italian] | GC 6936 |
| HOE-2824 | HSDB 1783 | LS-7742 |
| Liromatin | Lirostanol | NCGC00166128-01 |
| NCGC00260148-01 | NSC 76068 | NSC-76068 |
| NSC76068 | OMS 1020 | Phenostat A |
| Phentin acetate | Phentinoacetate | Q168685 |
| SCHEMBL68978 | Stannane, (acetyloxy)triphenyl- | Stannane, acetoxytriphenyl- |
| Suzu | TPTA | TPZA |
| TRIPHENYLTIN ACETATE | Tin triphenyl acetate | Tin, acetoxytriphenyl- |
| Tinestan | Tinestan 60 wp | Tinestan WP 20 |
| Tinestan WP 60 | Tox21_202600 | Trifenil stagno acetato |
| Trifenil stagno acetato [Italian] | Trifenyl-tinacetaat | Trifenyl-tinacetaat [Dutch] |
| Triphenyl-zinnacetat | Triphenyl-zinnacetat (german) | Triphenyl-zinnacetat [German] |
| Triphenylaceto stannane | Triphenylstannium acetate | Triphenyltin(IV) acetate |
| VP 19-40 | Vp 1940 | W-100342; |
| WLN: 1VO-SN-R&R&R | ZINC169795090 | acetoxy(triphenyl)stannane |
| m-Nitrobenzaldehyde 3-thio-4-o-tolylsemicarbazone | triphenylstannyl acetate |