Compound

D1134 | tributyltin benzoate

Molecular Formula C19H32O2Sn
Molecular Weight 411.2
Structure
Description organotin compound ( organic compounds that contain tin); inhibit ATP synthase

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 0.15±0.23 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 0.5 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 5.33±4.70 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


Reported as not meeting GHS hazard criteria by 1 of 40 companies. For more detailed information, please visit ECHA C&L website


Of the 2 notification(s) provided by 39 of 40 companies with hazard statement code(s):


H301+H311 (97.44%): Toxic if swallowed or in contact with skin [Danger Acute toxicity, oral


acute toxicity, dermal]


H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]


H311 (100%): Toxic in contact with skin [Danger Acute toxicity, dermal]


H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]


H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P260, P264, P270, P273, P280, P301+P310, P302+P352, P305+P351+P338, P312, P314, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Organism Test type Route Dose (normalized dose) Effect Source
rat LD50 oral 132mg/kg (132mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 934, 1969.
rat LD50 skin 503mg/kg (503mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 934, 1969.
mouse LD50 intravenous 178mg/kg (178mg/kg) U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00090,
mouse LD50 oral 108mg/kg (108mg/kg) Archiv fuer Toxikologie. Vol. 23, Pg. 283, 1968.


  • 4342-36-3 Benzoic acid, tributylstannyl ester Benzoyloxytributylstannane
    Biomet 11 C-55984 CAS-4342-36-3
    Caswell No. 867AA DSSTox_CID_14981 DSSTox_GSID_34981
    DSSTox_RID_79233 DTXSID5034981 EINECS 224-399-8
    EPA Pesticide Chemical Code 083106 KS-0000265S LS-146427
    NCGC00164179-01 NCGC00164179-02 NCGC00164179-03
    NCGC00257290-01 NSC 221308 NSC-221308
    NSC221308 Q27275993; Stannane, (benzoyloxy)tributyl-
    Stannane, benzoyloxytributyl- TRIBUTYLTIN BENZOATE Tin, (benzoyloxy)tributyl-
    Tin, (benzoyloxy)tributyl- (7CI) Tin, benzoate Tin, tributyl-, benzoate
    Tox21_303395 Tri-n-butyl-zinn benzoate Tri-n-butyl-zinn benzoate [German]
    Tri-n-butyltin benzoate Tributylstannyl benzoate Tributyltin benzoate, 98%
    Tris(n-butyl)tin benzoate WLN: 4-SN-4&4&OVR ZINC170172514
    tri-n-butylbenzoyloxytin

    CAS Number 4342-36-3
    PubChem Compound 16682834