Compound
D0653 | 2,6-di(butan-2-yl)phenol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 13.69±3.19 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 15.85 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Danger |
Aggregated GHS information provided by 103 companies from 2 notifications to the ECHA C&L Inventory. Reported as not meeting GHS hazard criteria by 65 of 103 companies. For more detailed information, please visit ECHA C&L website Of the 1 notification(s) provided by 38 of 103 companies with hazard statement code(s): H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rabbit | LDLo | intravenous | 10mg/kg (10mg/kg) | Journal of Medicinal Chemistry. Vol. 23, Pg. 1350, 1980. | |
| mouse | LD50 | intravenous | 60mg/kg (60mg/kg) | Journal of Medicinal Chemistry. Vol. 23, Pg. 1350, 1980. | |
| (-)-2,6-di-sec-butylphenol | 2,6-Di(sec-butyl)phenol | 2,6-Di-sec-butyl-phenol |
| 2,6-Di-sec-butylfenol | 2,6-Di-sec-butylfenol [Czech] | 2,6-Di-sec-butylphenol |
| 2,6-bis(butan-2-yl)phenol | 2,6-bis(methylpropyl)phenol | 2,6-di(butan-2-yl)phenol |
| 2,6-di-s-butyl-phenol | 4-06-00-03490 (Beilstein Handbook Reference) | 5510-99-6 |
| ACM31291608 | AKOS024286538 | BRN 2258305 |
| CAS-5510-99-6 | CHEMBL416393 | CTK5A3054 |
| DSSTox_CID_24440 | DSSTox_GSID_44440 | DSSTox_RID_80230 |
| DTXSID0044440 | Di-sec-butylphenol, mixed isomers | Di-sec-butylphenol, mixture of isomers, predom. 2,6-isomer; |
| EC 226-854-6 | EINECS 226-854-6 | FHTGJZOULSYEOB-UHFFFAOYSA-N |
| FT-0610723 | LS-104317 | MCULE-1481324611 |
| NCGC00255992-01 | P193 | PHENOL, 2,6-DI-sec-BUTYL- |
| Phenol, 2,6-bis(1-methylpropyl)- | Phenol,2,6-bis(1-methylpropyl)- | Q27269692 |
| SCHEMBL202738 | ST094896 | Tox21_302075 |
| CAS Number | 31291-60-8, 5510-99-6 |
| PubChem Compound | 21685 |