Compound

D0627 | 2,2'4,4'-tetrabromodiphenyl ether

Molecular Formula C12H6Br4O
Molecular Weight 485.79
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 22.56±5.18 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 39.81 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 25.56±34.73 rat hepatocytes MMP assay decrease IC50 163

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 oral 225mg/kg (225mg/kg) Journal of Medicinal Chemistry. Vol. 18, Pg. 553, 1975.
mouse LD50 intravenous 33mg/kg (33mg/kg) Journal of Medicinal Chemistry. Vol. 18, Pg. 553, 1975.


  • 0N97R5X10X 1,1'-Oxybis(2,4-dibromo-Benzene 1,1'-Oxybis[2,4-dibromobenzene]
    1,1'-Oxybis[2,4-dibromobenzene], 9CI 1,1'-oxybis(2,4-dibromobenzene) 2,2',4,4' tetrabromodiphenyl ether
    2,2',4,4'-TetraBDE 2,2',4,4'-Tetrabromodiphenyl ether 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47)
    2,2',4,4'-tetrabromodiphenylether 2,2'4,4'-Tetrabromodiphenyl ether 2,4-dibromo-1-(2,4-dibromophenoxy)benzene
    4,4'-Oxybis(1,3-dibromobenzene) 5436-43-1 7840AB
    AK121881 AKOS016011206 AX8064085
    BDE 47 BDE No 47 solution, 50 mug/mL in isooctane, analytical standard; BDE No 47, analytical reference material
    BDE-47 BDE-47(2,2',4,4'-Tetrabromodiphenyl Ether) Benzene, 1,1'-oxybis(2,4-dibromo-
    Benzene, 1,1'-oxybis[2,4-dibromo- C12H6Br4O C18205
    CAS-5436-43-1 CHEBI:81584 CHEMBL229760
    CTK8D9905 DIBROMOPHENYL ETHER DS-6407
    DSSTox_CID_10056 DSSTox_GSID_30056 DSSTox_RID_78835
    DTXSID3030056 HMS3039P04 KS-00000MIH
    LS-182277 MLS001065577 NCGC00090912-01
    NCGC00090912-02 NCGC00257881-01 NSC 21724
    NSC-21724 NSC21724 PBDE 47
    PBDE 47 (2,2',4,4'-Tetrabromodiphenyl ether) PBDE No. 47 PBDE No. 47 100 microg/mL in Methanol
    PBDE-47 Q27155474 QC-2733
    RW2836 SCHEMBL899494 SMR000568461
    Tox21_200327 UNII-0N97R5X10X UNII-1J1A90VP8W component XYBSIYMGXVUVGY-UHFFFAOYSA-N
    XYBSIYMGXVUVGY-UHFFFAOYSA-N ZINC1583785 bis(2,4-dibromophenyl) ether

    CAS Number 5436-43-1, 55921-66-9
    PubChem Compound 95170
    ChEBI 81584