Compound

D0594 | 1,4-benzenediamine

Molecular Formula C6H8N2
Molecular Weight 108.14
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 3.28±0.42 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 2.18 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H311: Toxic in contact with skin [Danger Acute toxicity, dermal]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H331: Toxic if inhaled [Danger Acute toxicity, inhalation]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P311, P312, P321, P322, P330, P333+P313, P337+P313, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

Aggregated GHS information provided by 553 companies from 24 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H301+H311+H331 (14.83%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral


acute toxicity, dermal


acute toxicity, inhalation]


H301 (99.82%): Toxic if swallowed [Danger Acute toxicity, oral]


H311 (99.82%): Toxic in contact with skin [Danger Acute toxicity, dermal]


H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]


H319 (99.82%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H331 (99.82%): Toxic if inhaled [Danger Acute toxicity, inhalation]


H370 (11.75%): Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H400 (92.59%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (99.82%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P260, P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P307+P311, P311, P312, P321, P322, P330, P333+P313, P337+P313, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H311: Toxic in contact with skin [Danger Acute toxicity, dermal]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H331: Toxic if inhaled [Danger Acute toxicity, inhalation]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P311, P312, P321, P322, P330, P333+P313, P337+P313, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H315: Causes skin irritation [Warning Skin corrosion/irritation]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H320: Causes eye irritation [Warning Serious eye damage/eye irritation]


H331: Toxic if inhaled [Danger Acute toxicity, inhalation]


H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P260, P261, P264, P270, P271, P272, P280, P285, P301+P310, P302+P352, P304+P340, P304+P341, P305+P351+P338, P307+P311, P311, P314, P321, P330, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H315: Causes skin irritation [Warning Skin corrosion/irritation]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]


H333: May be harmful if inhaled [Warning Acute toxicity, inhalation]


H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P260, P261, P264, P270, P271, P272, P280, P285, P301+P310, P302+P352, P304+P312, P304+P340, P304+P341, P305+P351+P338, P307+P311, P310, P312, P314, P321, P330, P332+P313, P333+P313, P342+P311, P362, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H320: Causes eye irritation [Warning Serious eye damage/eye irritation]


H331: Toxic if inhaled [Danger Acute toxicity, inhalation]


H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P260, P261, P264, P270, P271, P272, P273, P280, P285, P301+P310, P302+P352, P304+P340, P304+P341, P305+P351+P338, P307+P311, P311, P314, P321, P330, P333+P313, P337+P313, P342+P311, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 1,4 phenylene diamine 1,4-BENZENEDIAMINE 1,4-Benzenediamine
    1,4-DIAMINO-BENZENE 1,4-Diaminobenzene 1,4-Diaminobenzene
    1,4-Phenylenediamine 1,4-Phenylenediamine 1,4-Phenylenediamine 1000 microg/mL in Acetonitrile
    1,4-Phenylenediamine 2000 microg/mL in Acetonitrile 1,4-Phenylenediamine-13N2 1,4-diamino benzene
    106-50-3 4-Aminoaniline 4-Phenylenediamine
    4-amino-aniline 4-aminophenylamine 4-phenylene diamine
    AB1002877 ACMC-1CUCB ACT07286
    AI3-00710 AKOS005716327 ANW-15356
    AS00466 ATTERCOP-CHM AT126215 Aminogen II
    BASF ursol D BBL011602 Benzofur D
    C.I. 76060 C.I. 76076 (Salt/Mix) C.I. Developer 13
    C.I. Oxidation Base 10 C19499 CAS-106-50-3
    CBCKQZAAMUWICA-UHFFFAOYSA-N CCRIS 509 CHEBI:51403
    CHEMBL403741 CI 76060 CI Developer 13
    CI Oxidation Base 10 CTK0H4606 DB14141
    DSSTox_CID_1138 DSSTox_GSID_21138 DSSTox_RID_75969
    DTXSID9021138 Developer 13 Developer PF
    Durafur Black R EC 203-404-7 EINECS 203-404-7
    EN300-19064 Epitope ID:114080 F0001-0125
    FT-0606928 FUR Brown 41866 Fenylenodwuamina
    Fenylenodwuamina [Polish] Fouramine D Fourrine 1
    Fourrine D Fur Black 41866 Fur Black 41867
    Fur Yellow Furro D Futramine D
    HSDB 2518 HSDB 6256 (Salt/Mix) I809
    InChI=1/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H JAROCOL PPD KS-00000V64
    KSC174M0N LABOTEST-BB LTBB002107 LS-402
    MCULE-9588027148 MFCD00007901 NCGC00159375-02
    NCGC00159375-03 NCGC00159375-04 NCGC00159375-05
    NCGC00256482-01 NCGC00259542-01 NE10526
    NSC 4777 NSC-4777 NSC4777
    Nako H OTAVA-BB 1509975 Orsin
    Oxidation base 10 P-PHENYLENE DIAMINE P0170
    PARA PHENYLENE DIAMINE PHENYLENEDIAMINE, P- Paraphenylen-diamine
    Paraphenylenediamine Pelagol D Pelagol DR
    Pelagol Grey D Peltol D Phenylenediamine, para
    Phenylenediamine, para- Phenylenediamines PubChem22180
    Q415024 RTR-013269 Renal PF
    Rodol D SC-77433 SCHEMBL27981
    ST2419110 STL163334 STR01091
    Santoflex IC Santoflex LC TRA0038404
    Tertral D Tox21_111615 Tox21_111615_1
    Tox21_201993 Tox21_302943 U770QIT64J
    UN 1673 UNII-TJX894Z2PK component CBCKQZAAMUWICA-UHFFFAOYSA-N UNII-U770QIT64J
    Ursol D Usaf ek-394 WLN: ZR DZ
    Z426537038 ZINC8294962 Zoba Black D
    benzene-1,4-diamine p-Aminoaniline p-Benzenediamine
    p-Diaminobenzene p-Fenylendiamin p-Fenylendiamin [Czech]
    p-Phenyldiamine p-Phenylenediamine p-Phenylenediamine [UN1673] [Keep away from food]
    p-Phenylenediamine [UN1673] [Keep away from food] p-Phenylenediamine, 99+% p-Phenylenediamine, >=99.0% (GC/NT)
    p-Phenylenediamine, flakes, >=99.5% p-Phenylenediamine, sublimed, >=99% p-Phenylenediamine, technical, >=97.0% (GC/NT)
    p-Phenylenediamine, zone-refined, purified by sublimation, >=99%; p-phenylendiamine p-phenylene-diamine
    p-phenylenediamine base para-diaminobenzene para-phenylene diamine
    para-phenylenediamine paraphenylene diamine paraphenylene-diamine

    CAS Number 106-50-3, 119516-82-4, 119516-83-5, 3114-70-3, 688-78-8
    PubChem Compound 7814
    KEGG Compound ID C19499
    ChEBI 51403