D1035 | p,p'-dde
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 25.60±1.71 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 44.67 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
   |
Danger |
Aggregated GHS information provided by 17 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 1 of 17 companies. For more detailed information, please visit ECHA C&L website Of the 4 notification(s) provided by 16 of 17 companies with hazard statement code(s): H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H311 (50%): Toxic in contact with skin [Danger Acute toxicity, dermal] H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation] H331 (50%): Toxic if inhaled [Danger Acute toxicity, inhalation] H332 (50%): Harmful if inhaled [Warning Acute toxicity, inhalation] H400 (87.5%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (37.5%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P311, P312, P321, P322, P330, P332+P313, P361, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H350: May cause cancer [Danger Carcinogenicity] H360: May damage fertility or the unborn child [Danger Reproductive toxicity] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P264, P270, P273, P281, P301+P312, P308+P313, P314, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | oral | 880mg/kg (880mg/kg) | Journal of Pharmaceutical Sciences. Vol. 63, Pg. 1068, 1974. | |
| 1,1'-(2,2-dichloroethene-1,1-diyl)bis(4-chlorobenzene) | 1,1'-(Dichloroethenylidene)bis(4-chlorobenzene) | 1,1'-(Dichloroethenylidene)bis[4-chlorobenzene] |
| 1,1'-(Dichlorovinylidene)bis(chlorobenzene) | 1,1'-Bis(chlorophenyl)-2,2-dichloroethylene | 1,1-BIS(CHLOROPHENYL)-2,2-DICHLOROETHYLENE |
| 1,1-Bis(p-chlorophenyl)-2,2-dichloroethylene | 1,1-DICHLORO-2,2-BIS(PARA-CHLOROPHENYL)ETYLENE | 1,1-Dichloro-2,2-bis(4'-chlorophenyl)ethylene |
| 1,1-Dichloro-2,2-bis(4'-chlorophenyl)ethylene (DDE) | 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethene | 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethene 99% |
| 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethene, 99% | 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene | 1,1-Dichloro-2,2-bis(p-chlorophenyl)ethene |
| 1,1-Dichloro-2,2-bis(p-chlorophenyl)ethylene | 1,1-Dichloro-2,2-bis(para-chlorophenyl) ethylene | 1,1-Dichloro-2,2-di(p-chlorophenyl)ethylene |
| 1,2-bis(p-chlorophenyl)ethene | 1,2-bis(p-chlorophenyl)ethylene | 1,2-di(p-chlorophenyl)ethylene |
| 1-Chloro-4-[2,2-dichloro-1-(4-chlorophenyl)vinyl]benzene | 1-Chloro-4-[2,2-dichloro-1-(4-chlorophenyl)vinyl]benzene # | 1-[2,2-Bis(Chloranyl)-1-(4-Chlorophenyl)ethenyl]-4-Chloranyl-Benzene |
| 1-chloro-4-[2,2-dichloro-1-(4-chlorophenyl)ethenyl]benzene | 2,2-Bis(4-chlorophenyl)-1,1-dichloroethene | 2,2-Bis(4-chlorophenyl)-1,1-dichloroethylene |
| 2,2-Bis(chlorophenyl)-1,1-dichloroethylene | 2,2-Bis(p-chlorophenyl)-1,1-dichloroethylene | 2,2-bis(p-chlorophenyl)-1,1-dichloroethene |
| 4,4'-DDE | 4,4'-DDE (1,1-Dichloro-2,2-bis(p-chlorophenyl)ethene) | 4,4'-DDE 10 microg/mL in Acetonitrile |
| 4,4'-DDE 10 microg/mL in Cyclohexane | 4,4'-DDE 100 microg/mL in Cyclohexane | 4,4'-DDE 1000 microg/mL in Toluene |
| 4,4'-DDE solution, 20 mug/mL in methanol, analytical standard | 4,4'-DDE solution, 200 mug/mL in isooctane, analytical standard | 4,4'-DDE solution, certified reference material, 5000 mug/mL in methanol |
| 4,4'-DDE, PESTANAL(R), analytical standard | 4,4-DDE | 4.4-DDE |
| 4M7FS82U08 | 68679-99-2 | 6WS; |
| 72-55-9 | A19100 | ACMC-209onl |
| AI3-01715 | AKOS015902433 | ANW-36223 |
| B0133 | BDBM50410512 | BIDD:ER0615 |
| BIDD:PXR0109 | BRN 1913355 | BSPBio_002501 |
| Benzene, 1,1'-(2,2-dichloroethenylidene)bis(chloro- | Benzene, 1,1'-(2,2-dichloroethenylidene)bis[chloro- | Benzene, 1,1'-(dichloroethenylidene)bis(4-chloro- |
| Benzene, 1,1'-(dichloroethenylidene)bis(4-chloro- (9CI) | Benzene, 1,1'-(dichloroethenylidene)bis(chloro- | Benzene, 1,1'-(dichloroethenylidene)bis[4-chloro- |
| Benzene,1'-(dichloroethenylidene)bis[4-chloro- | C04596 | CAS-72-55-9 |
| CCG-39403 | CCRIS 193 | CHEBI:16598 |
| CHEMBL363207 | CTK8B2236 | DDE |
| DDE (VAN) | DDE(p,p') | DDE, p,p'- |
| DDT dehydrochloride | DSSTox_CID_374 | DSSTox_GSID_20374 |
| DSSTox_RID_75550 | DTXSID9020374 | Dichlorodiphenyl Dichloroethylene |
| Dichlorodiphenyl dichloroethene | DivK1c_006678 | EINECS 200-784-6 |
| EINECS 272-060-8 | ETHYLENE, 2,2-BIS(CHLOROPHENYL)-1,1-DICHLORO- | Ethylene, 1,1-dichloro-2,2-bis(p-chlorophenyl)- |
| Ethylene,1-dichloro-2,2-bis(p-chlorophenyl)- | FT-0609172 | HMS2230C07 |
| HMS3369G06 | HSDB 1625 | KBio1_001622 |
| KBio2_002487 | KBio2_005055 | KBio2_007623 |
| KBio3_002001 | KBioGR_001221 | KBioSS_002495 |
| KS-000017LU | LS-1616 | LS-68298 |
| MLS001055473 | MLS002152918 | NCGC00090888-01 |
| NCGC00090888-02 | NCGC00090888-03 | NCGC00090888-04 |
| NCGC00090888-05 | NCGC00090888-06 | NCGC00090888-07 |
| NCGC00090888-08 | NCGC00090888-09 | NCGC00090888-10 |
| NCGC00254155-01 | NCGC00258812-01 | NCI-C00555 |
| NSC 1153 | NSC-1153 | NSC1153 |
| P,P'-DICHLORODIPHENYLDIC HLOROETHYLENE (DDE) | Q409592 | SCHEMBL177472 |
| SMR001224518 | SPBio_001710 | SPECTRUM330072 |
| SpecPlus_000582 | Spectrum2_001865 | Spectrum3_000861 |
| Spectrum4_000701 | Spectrum5_002042 | Spectrum_001941 |
| TR-031309 | Tox21_201260 | Tox21_300109 |
| UCNVFOCBFJOQAL-UHFFFAOYSA-N | UNII-4M7FS82U08 | WLN: GYGUYR DG&R DG |
| ZINC1530006 | dichlorodiphenyldichloroethylene | p,2-dichloroethylene |
| p,p' -DDE | p,p'-(Dichlorodiphenyl)-2,2-dichloroethylene | p,p'-(Dichlorodiphenyl)dichloroethylene |
| p,p'-:dde | p,p'-DDE | p,p'-DDE (p,p'-Dichlorodiphenyldichloroethylene) |
| p,p'-DDT mixture | p,p'-Dichlorodiphenoldichloroethylene | p,p'-Dichlorodiphenyl dichloroethylene |
| p,p'-Dichlorodiphenyldichloroethylene | p,p'-Dichlorodiphenyldichloroethylene (DDE) | p,p-Dde |
| p,p[-DDE | p,p`-DDE | para,para'-DDE |
| s5437 |