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Compound

D0875 | dibutyltin dilaurate

Molecular Formula C32H64O4Sn
Molecular Weight 631.6
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL human qHTS-HepG2 MMP assay Negative IC50 163
MEMBRANE POTENTIAL 27.48 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 22.41±7.17 rat hepatocytes MMP assay decrease IC50 163

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 intraperitoneal 180mg/kg (180mg/kg) Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (4), Pg. 36, 1995.
rat LDLo intraperitoneal 85mg/kg (85mg/kg) British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 16, 1955.
rabbit LD50 oral 100mg/kg (100mg/kg) "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 66, 1999.
rabbit LD skin > 2gm/kg (2000mg/kg) National Technical Information Service. Vol. OTS0555424,
rat LD50 oral 175mg/kg (175mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 44, 1960.
mouse LC50 inhalation 150mg/m3/2H (150mg/m3) "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 66, 1999.
rat LD50 intravenous 33mg/kg (33mg/kg) "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 66, 1999.
mouse LD50 oral 210mg/kg (210mg/kg) Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (4), Pg. 36, 1995.
mammal (species unspecified) LC50 inhalation 2400mg/m3 (2400mg/m3) Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (4), Pg. 36, 1995.


  • ACMC-1BH4P AKOS015909826 ANW-37061
    CTK2H7090 D0303; DBTDL
    Di-n-butyldilauryltin KS-00000V6C KSC377A9B
    RTR-024785 SC-18233 SCHEMBL35315
    TR-024785 di-butyltin dilaurate di-n-butyl tin dilaurate
    dibutyl tin laurate dibutyl-tin dilaurate dibutyltindilaurate

    CAS Number 77-58-7
    PubChem Compound 9809426