Compound

D0955 | halobetasol propionate

Molecular Formula C25H31ClF2O5
Molecular Weight 485
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 15.18±5.52 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 13.77 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 25.21±7.02 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 4 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H315 (25%): Causes skin irritation [Warning Skin corrosion/irritation]


H319 (25%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H341 (50%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H361 (75%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]


H372 (50%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P201, P202, P260, P264, P270, P280, P281, P302+P352, P305+P351+P338, P308+P313, P314, P321, P332+P313, P337+P313, P362, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate (6|A,11|A,16|A)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione 21-Chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
    66852-54-8 852H548 91A0K1TY3Z
    AB01566925_01 AB2000750 AKOS025310143
    API0002882 BDSYKGHYMJNPAB-LICBFIPMSA-N BMY 30056
    BMY-30056 BMY-30056;CGP-14458;Ulobetasol propionate CAS-66852-54-8
    CGP-14,458 CGP-14458 CHEBI:135782
    CHEMBL1200908 CS-4305 CTK8G0126
    D04409 DSSTox_CID_26636 DSSTox_GSID_46636
    DSSTox_RID_81782 DTXSID6046636 HALOBETASOL PROPIONATE
    HY-B0878 Halobetasol (propionate) Halobetasol propionate (USAN)
    Halobetasol propionate [USAN:USP] Halobetasolpropionate Miracorten
    Miracorten NCGC00167451-01 NCGC00373230-02
    Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6alpha,11beta,16beta)- SC-18329 SCHEMBL33858
    SR-01000942239 SR-01000942239-1 Tox21_112455
    UNII-91A0K1TY3Z Ulobetasol propionate Ulobetasol propionate
    Ultravate Ultravate (TN) Ultravate;
    ZINC3920028 [(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate halobetasol-propionate
    s4089

    CAS Number 66852-54-8
    PubChem Compound 6918178
    KEGG Drug D04409
    ChEBI 135782