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Compound

D0950 | geliomycin

Molecular Formula C22H16O6
Molecular Weight 376.4
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 0.52±0.04 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 0.19 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 0.55±0.31 rat hepatocytes MMP assay decrease IC50 163

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 intraperitoneal 20mg/kg (20mg/kg) "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 3, Pg. 351, 1980.
mouse LD50 oral 2gm/kg (2000mg/kg) "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 3, Pg. 354, 1980.


  • 1,2-Dihydro-1,1,9-trimethyl-3,5,7,10-tetrahydroxy-6H-benzo[c,d]pyrene-2,6-dione 11029-70-2 20004-62-0
    2H-Benzo(cd)pyrene-2,6(1H)-dione, 3,5,7,10-tetrahydroxy-1,1,9-trimethyl- 2H-Benzo[cf]pyrene-2,6(1H)-dione,3,5,7,10-tetrahydroxy-1,1,9-trimethyl- 3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-1H-benzo[cd]pyrene-2,6-dione
    3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-2H-benzo[cd]pyrene-2,6(1H)-dione 3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-2H-benzo[cd]pyrene-2,6(1H)-dione #; 4-08-00-03704 (Beilstein Handbook Reference)
    7N3A092A5X A 3733A ABLACSIRCKEUOB-UHFFFAOYSA-N
    ACM20004620 AKOS000715231 Antibiotic A 3733A
    Antibiotic obtained from cultures of Actinomyces flavochromogenes var. heliomycini or the same substance obtained by any other means BBL016487 BRD-K64517075-001-01-9
    BRN 2187224 C12080 CAS-20004-62-0
    CHEBI:29671 CHEMBL1320139 CTK8G2929
    Croceomycin DSSTox_CID_26101 DSSTox_GSID_46101
    DSSTox_RID_81339 DTXSID4046101 Geliomitsin
    Geliomycin Heliomicina Heliomicina [INN-Spanish]
    Heliomycin Heliomycin (Salt/Mix) Heliomycin [INN]
    Heliomycine Heliomycine [INN-French] Heliomycinum
    Heliomycinum [INN-Latin] Itamycin J-012937
    LS-40015 LS-74106 MCULE-5498366880
    NCGC00160275-01 NCGC00160275-01!RESISTOMYCIN NCGC00160275-02
    NCGC00160275-03 NCGC00160672-01 NP285
    Q27110219 Resistomycin SCHEMBL2134180
    SR-01000318568 SR-01000318568-1 ST50338003
    STK177255 Tox21_111753 Tox21_111753_1
    UNII-7N3A092A5X X-340 ZINC100150837

    CAS Number 11029-70-2, 20004-62-0
    PubChem Compound 135430323