Compound

D0132 | 3-NPA

Molecular Formula C3H5NO4
Molecular Weight 119.08
Structure
Description mycotoxin; a potent mitochondrial inhibitor; irreversibly inactivates SDH

Toxicity Dose Time Species Model Method Action Positive criterion Reference
GLUCOSE GALACTOSE IC50 RATIO permeabilized LUHMES cells Assessment of the function of individual mitochondrial complexes using Agilent Seahorse XFe24 EC25(NA) [Glc/Gal] 326

Target Dose Time Species Model Method Action Positive criterion Reference
Quinol--cytochrome-c reductase permeabilized LUHMES cells Assessment of the function of individual mitochondrial complexes using Agilent Seahorse XFe24 inhibit EC25(NA) [Glc/Gal] 326

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]


H315 (97.44%): Causes skin irritation [Warning Skin corrosion/irritation]


H319 (97.44%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335 (97.44%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • .beta.-Nitropropionic acid 13104-55-7 3-NP
    3-NP acid 3-NPA 3-Nitro-Propanoic acid
    3-Nitroporpionic Acid 3-Nitropropanoic acid 3-Nitropropanoic acid
    3-Nitropropionate 3-Nitropropionic acid, 8CI 3-Nitropropionic acid, 97%
    3-Nitropropionic acid, >=97% 3-nitro-1-propionate 3-nitro-propionic acid
    3-nitropropanoate 3-nitropropionic acid 3-nitropropionic-acid
    4-02-00-00771 (Beilstein Handbook Reference) 504-88-1 504-88-1 (FREE ACID)
    6949AB AKOS006221915 AKOS015833440
    BCP15066 BDBM82201 BNP
    BOVINOCIDIN (3-nitropropionic acid) BRN 1759889 BSPBio_002685
    Bovinocidin C-31013 C05669
    CAS-504-88-1 CC-15785 CCG-40325
    CCRIS 454 CHEBI:16348 CHEMBL451226
    CM10288 CS-W013591 CTK3I9712
    DB-008848 DSSTox_CID_982 DSSTox_GSID_20982
    DSSTox_RID_75904 DTXSID1020982 DivK1c_006788
    EINECS 208-003-0 EU-0100838 FCH3459604
    FT-0632243 HMS2235N03 HMS3262H17
    HMS3369D16 HSDB 4147 HY-W012875
    Hiptagenic acid KBio1_001732 KBio2_002154
    KBio2_004722 KBio2_007290 KBio3_001905
    KBioGR_001598 KBioSS_002154 KS-0000184K
    LP00838 LS-1311 Lopac-N-5636
    Lopac0_000838 MFCD00007406 MLS001066410
    N 5636 NCGC00015744-01 NCGC00015744-02
    NCGC00015744-03 NCGC00015744-04 NCGC00015744-05
    NCGC00015744-06 NCGC00015744-07 NCGC00094169-01
    NCGC00094169-02 NCGC00094169-03 NCGC00094169-04
    NCGC00256389-01 NCGC00260009-01 NCGC00261523-01
    NCI-C03076 NITROPROPIONIC ACID, BETA NSC 64266
    NSC-64266 NSC64266 Nitropropionic aci, beta
    Nitropropionic acid, .beta. OE</=-nitropropionic acid Propanoic acid, 3-nitro-
    Propanoic acid, 3-nitro- (9CI) Propionic acid, 3-nitro- Q223104
    QY4L0FOX0D RTR-031911 SC-89718
    SCHEMBL70072 SDCCGMLS-0066769.P001 SMR000471863
    SPBio_000951 SPECTRUM1504206 SR-01000076030
    SR-01000076030-1 SR-01000076030-5 SpecPlus_000692
    Spectrum2_000876 Spectrum3_000993 Spectrum4_001119
    Spectrum5_001895 Spectrum_001674 Substrate analogue, 20
    TR-031911 TRA0076505 Tox21_202460
    Tox21_303007 Tox21_500838 UNII-QY4L0FOX0D
    WBLZUCOIBUDNBV-UHFFFAOYSA-N WLN: WN2VQ ZINC895862
    beta -nitropropionic acid beta-Nitropropanoate beta-Nitropropanoic acid
    beta-Nitropropionic acid

    CAS Number 13104-55-7, 504-88-1, 52130-87-7
    PubChem Compound 1678
    KEGG Compound ID C05669
    ChemSpider 1615
    Wikipedia beta-Nitropropionic acid

    1. Mandavilli et al., 2005