D0153 | Tebufenpyrad
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| ELECTRON TRANSPORT CHAIN | 6 nM | NADH–Q-1 | decrease | IC50 | 108 | |||
| GLUCOSE GALACTOSE IC50 RATIO | 2700 | LUHMES (Lund human mesencephalic) cells | Glc–Gal–NeuriTox assay | EC25(NA) [Glc/Gal] | 326 | |||
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| NADH:ubiquinone reductase | 6 nM | NADH–Q-1 | inhibitor | IC50 | 108 | |||
| NADH:ubiquinone reductase | 2700 | LUHMES (Lund human mesencephalic) cells | Glc–Gal–NeuriTox assay | EC25(NA) [Glc/Gal] | 326 | |||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
    |
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P260, P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P312, P304+P340, P312, P314, P321, P330, P333+P313, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
Aggregated GHS information provided by 287 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301 (85.71%): Toxic if swallowed [Danger Acute toxicity, oral] H302 (14.29%): Harmful if swallowed [Warning Acute toxicity, oral] H317 (85.71%): May cause an allergic skin reaction [Warning Sensitization, Skin] H332 (86.76%): Harmful if inhaled [Warning Acute toxicity, inhalation] H373 (85.71%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H400 (85.71%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (85.71%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P260, P261, P264, P270, P271, P272, P273, P280, P301+P310, P301+P312, P302+P352, P304+P312, P304+P340, P312, P314, P321, P330, P333+P313, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P260, P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P312, P304+P340, P312, P314, P321, P330, P333+P313, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H320: Causes eye irritation [Warning Serious eye damage/eye irritation] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P309+P311, P312, P314, P321, P330, P333+P313, P337+P313, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H320: Causes eye irritation [Warning Serious eye damage/eye irritation] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure Narcotic effects] H351: Suspected of causing cancer [Warning Carcinogenicity] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P281, P301+P310, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P309+P311, P312, P314, P321, P330, P333+P313, P337+P313, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| 119168-77-3 | 168T773 | 1H-Pyrazole-5-carboxamide, 4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl- |
| 1H-Pyrazole-5-carboxamide, 4-chloro-N-[[4-(1,1-dimethylethyl)phenyl]methyl]-3-ethyl-1-methyl- | 4-Chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide | A804212 |
| AB0011825 | AC 801757 | AKOS015895772 |
| AS-12374 | AX8152491 | C11126 |
| CAS-119168-77-3 | CHEBI:9422 | CHEMBL1897070 |
| Comanche | DSSTox_CID_14223 | DSSTox_GSID_34223 |
| DSSTox_RID_79126 | DTXSID0034223 | FT-0603186 |
| HSDB 7271 | IRU3P7ZB3F | InChI=1/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) |
| K-1355 | LS-128147 | MK 239 |
| MK239 | N-(4-(tert-Butyl)benzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide | N-(4-t-Butylbenzyl)-4-chloro-3-ethyl-1-methylpyrazole-5-carboxamide |
| N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide | N-(p-tert-butylbenzyl)-4-chloro-3-ethyl-1-methylpyrazole-5-carboxamide | N-[(4-tert-butylphenyl)methyl]-4-chloranyl-5-ethyl-2-methyl-pyrazole-3-carboxamide |
| N-[(4-tert-butylphenyl)methyl]-4-chloro-5-ethyl-2-methyl-3-pyrazolecarboxamide | N-[(4-tert-butylphenyl)methyl]-4-chloro-5-ethyl-2-methylpyrazole-3-carboxamide | NCGC00168338-01 |
| NCGC00168338-02 | NCGC00254940-01 | Pesticide4_Tebufenpyrad_C18H24ClN3O_1H-Pyrazole-5-carboxamide, 4-chloro-N-[[4-(1,1-dimethylethyl)phenyl]methyl]-3-ethyl-1-methyl- |
| Pyranica | Q285594 | SCHEMBL26848 |
| TR-022882 | TR-022926 | Tebufenpyrad |
| Tebufenpyrad 10 microg/mL in Acetonitrile | Tebufenpyrad 10 microg/mL in Cyclohexane | Tebufenpyrad 100 microg/mL in Cyclohexane |
| Tebufenpyrad [ISO] | Tebufenpyrad, PESTANAL(R), analytical standard | Tox21_301038 |
| UNII-IRU3P7ZB3F | ZINC967721 | ZZYSLNWGKKDOML-UHFFFAOYSA- |
| ZZYSLNWGKKDOML-UHFFFAOYSA-N |
| CAS Number | 119168-77-3, 68459-97-2, 68716-49-4 |
| PubChem Compound | 86354 |
| KEGG Compound ID | C11126 |
| ChEBI | 9422 |
| ChemSpider | 77872 |
| Wikipedia | Tebufenpyrad |