Compound
D0225 | Peroxynitrite
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| NADH:ubiquinone reductase | 2mM, IC50=1.52mM | rat | heart mitochondria | rate of NADH-dependent ferrycynide reduction at 420nm | inhibit | IC50 | 298 | |
| Succinate dehydrogenase | 2mM, IC50=0.9mM | rat | heart mitochondria | spectrophotometrically with DCPIP at 600nm | inhibit | IC50 | 298 | |
| Cytochrome c oxidase | 2mM | rat | heart mitochondria | oxidation of reduced cytochrome c oxidase at 550nm | Negative | 298 | ||
| ATP synthase | 2mM, IC50=0.63mM | rat | heart mitochondria | ATPase activity was assayed by coupling to the reactions of pyruvate kinase with lactace dehydrogenase following NADH oxidation at 340nm | inhibit | IC50 | 298 | |
| 19059-14-4 | C16845 | CHEBI:25941 |
| CMFNMSMUKZHDEY-UHFFFAOYSA-M | CTK0H5961 | DTXSID10172540 |
| LS-102485 | ONOO- | Oxoperoxonitrate(1-) |
| Peroxonitrous acid anion | Peroxynitrite (8CI,9CI) | Peroxynitrosyl (NO3) (6CI) |
| Q419130 | [NO(OO)](-) | oxidoperoxidonitrate(1-) |
| peroxynitrite ion |
| CAS Number | 19059-14-4 |
| PubChem Compound | 104806 |
| KEGG Compound ID | C16845 |
| ChEBI | 25941 |
| PharmGKB | PA166178652 |
| ChemSpider | 94607 |
| Wikipedia | Peroxynitrite |
1. Ballinger et al., 2000