Search References Drug Actions/Targets About Access data Feedback
Sign In
mitontu@gmail.com
2021 MitoTox | (CC BY-NC 4.0)
Drug

D0276 | o-phenanthroline

Molecular Formula C12H8N2
Molecular Weight 180.2
Structure
State solid
Description metal chelator

Toxicity Dose Time Species Model Method Action Positive criterion Reference
ELECTRON TRANSPORT CHAIN 0.25 mM NADH–Q decrease IC50 130

Target Dose Time Species Model Method Action Positive criterion Reference
NADH:ubiquinone reductase 0.25 mM NADH–Q inhibitor IC50 130

Pictogram Signal Statements Precautionary Statement Codes
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


 P264, P270, P273, P301+P310, P321, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

Aggregated GHS information provided by 986 companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H301 (99.9%): Toxic if swallowed [Danger Acute toxicity, oral]


H400 (99.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (99.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


 P264, P270, P273, P301+P310, P321, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


 P264, P270, P273, P301+P310, P321, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • DrugBank Name 1,10-Phenanthroline
    DrugBank DB02365
    CAS Number 12678-01-2, 14634-91-4, 3829-86-5, 5144-89-8, 527-72-0, 66-71-7
    PubChem Compound 1318
    KEGG Compound ID C00604
    ChEBI 44975
    ChemSpider 1278
    BindingDB 50092158.0
    Wikipedia Phenanthroline