MITOTOX

Compound

D0438 | aminooxyacetate

Properties

Molecular Formula	C2H5NO3
Molecular Weight	91.07
Structure
Trade names	Aminooxyacetate Acid
Description	GABA transaminase (GABA-T) inhibitor that induces GABA accumulation ; a general inhibitor of pyridoxal phosphate (PLP)-dependent enzymes (by attacking the Schiff base linkage between PLP and the enzyme, forming oxime type complexes)

Therapeutic Classification Source: DrugBank

Targets

Target	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
Aspartate aminotransferase, mitochondrial			Dunkin-Hartley strain guinea pigs	Synaptosomes from cerebral cortices		inhibitor		198

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Warning	Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (97.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Warning

Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (97.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure

Respiratory tract irritation]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Indications Source: SIDER

Synonyms Source: PubChem

(Carboxymethoxy)amine	(aminooxy)acetic acid	(o-Carboxymethyl)hydroxylamine
106809-EP2272537A2	106809-EP2295407A1	106809-EP2298736A1
1239AJ	14I68GI3OQ	2-(Aminooxy)acetic acid
2-(Aminooxy)acetic acid pound>>AOAA pound>>U 7524 pound>>U7524	2-(aminoxy)acetic acid	396FBBC5-D28E-448C-A696-BF9163EA8B1A
645-88-5	AB00172543-06	ACETIC ACID, (AMINOOXY)-
AKOS015919037	AOA	AOA hemihydrochloride
AOAA	Acetic acid, aminooxy-	Acetic acid,2-(aminooxy)-
Aminooxy-acetic acid	Aminooxyacetate	Aminooxyacetate Acid
Aminooxyacetic acid	BCP30347	BRN 0878238
CCG-204103	CHEMBL347862	CTK5C1432
Carboxymethoxyamine	DB02079	DTXSID50214756
GTPL5136	Hydroxylamine, O-(carboxymethyl)-	J-650057
LS-10973	Lopac-A-4508	Lopac0_000007
MCULE-4566186819	Methoxyamine, 1-carboxy-	NCGC00015058-01
NCGC00015058-02	NCGC00015058-03	NCGC00162041-01
NE62756	NQRKYASMKDDGHT-UHFFFAOYSA-N	Q4746466
SR-01000075676	SR-01000075676-1	STL197511
U 7524	U-7524 pound>>Hydroxylamine, O-(carboxymethyl)-;	UNII-14I68GI3OQ
ZINC4689151	amino-oxyacetic acid	aminoxy-acetic acid
aminoxyacetic acid	carboxymethoxylamine	hydroxylamine acetic acid
u-7524

External IDs

DrugBank Name	Aminooxyacetic acid
CAS Number	1246817-66-2, 20295-82-3, 2921-14-4, 645-88-5, 66304-03-8
PubChem Compound	286
ChEBI	347862
ChemSpider	280
Wikipedia	Aminooxyacetic acid