Compound

D0473 | pentamidine

Molecular Formula C23H36N4O10S2
Molecular Weight 592.7
Structure
Trade names Nebupent, Pentam,
Description antimicrobial

P

P01CX01 Pentamidine isethionate


[P01CX] Other agents against leishmaniasis and trypanosomiasis


[P01C] AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS


[P01] ANTIPROTOZOALS


[P] Antiparasitic products, insecticides and repellents


Toxicity Dose Time Species Model Method Action Positive criterion Reference
UNCOUPLING increase 51
ELECTROPHORETIC UNCOUPLING 278
ELECTRON TRANSPORT CHAIN decrease 51

Pictogram Signal Statements Precautionary Statement Codes
Warning

Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]


H317 (97.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]


H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P264, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 1,5-Bis(p-amidinophenoxy)pentane bis(2-hydroxyethanesulfonate salt) 1,5-Bis(p-amidinophenoxy)pentane bis(2-hydroxyethanesulfonate salt). 140-64-7
    140P647 2-Hydroxyethane-1-sulfonic acid--4,4'-[pentane-1,5-diylbis(oxy)]di(benzene-1-carboximidamide) (2/1) 2512 R.P.
    4,4'-(Pentamethylenedioxy)-dibenzamidine bis(2-hydroxyethanesulfonate) 4,4'-(Pentamethylenedioxy)dibenzamidine bis(2-hydroxyethanesulfonate) 4,4'-(Pentamethylenedioxy)dibenzamidine bis-2-hydroxyethanesulfonate salt
    4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate) 4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate);4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate) 4,4'-(pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethane-1-sulfonate)
    4,4'-Diamidino-alpha,omega-diphenoxypentane isethionate 4,4'-Diamidinodiphenoxypentane di(beta-hydroxyethanesulfonate) 4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide bis(2-hydroxyethanesulfonic acid)
    4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide bis(2-hydroxyethylsulfonate) 4-[5-(4-amidinophenoxy)pentyloxy]benzenecarboxamidine, 2-hydroxyethanesulfonic acid, 2-hydroxyethanesulfonic acid; 4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;2-hydroxyethanesulfonic acid
    4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide 4CH-018037 AB0015398
    AK-51766 AKOS015914189 ANW-48586
    API0003784 AX8027505 BR-51766
    Benzamidine, 4,4'-(pentamethylenedioxy)di-, bis(beta-hydroxyethanesulfonate) C-23299 C23H36N4O10S2
    CAS-140-64-7 CCG-39715 CCRIS 1660
    CHEBI:7977 CHEMBL361506 CS-4133
    CTK8B5397 D00834 DSSTox_CID_3796
    DSSTox_GSID_23796 DSSTox_RID_77194 DTXSID5023796
    Diamidine EINECS 205-424-1 Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-(1,5-pentanediylbis(oxy))bis(benzenecarboximidamide) (2:1)
    FT-0631814 HMS1569P07 HMS1921M19
    HMS2096P07 HMS3713P07 HMS501D11
    HY-B0537B KS-00000Z9I KS-5289
    Lomidin Lomidine Lomidine isoethionate
    M & B 800 M808 MB 800
    MCULE-6357662093 MFCD00079213 NCGC00017022-01
    NCGC00017022-02 NCGC00017022-03 NCGC00017022-04
    NCGC00017022-05 NCGC00091927-01 NCGC00091927-02
    NCGC00091927-03 NCGC00091927-04 NCGC00179034-07
    NCGC00254121-01 NCGC00259271-01 OCZ103-OS
    P-155 PENTAM PENTAMIDINE ISETHIONATE
    Pentacarinat Pentam 300 (TN) Pentamidin-Isethionat
    Pentamidine (isethionate) Pentamidine diisethionate Pentamidine diisetionate
    Pentamidine diisetionate, European Pharmacopoeia (EP) Reference Standard Pentamidine isethionate (USAN) Pentamidine isethionate [USAN:USP]
    Pentamidine isethionate salt Pentamidine isethionate salt, 97% Pentamidine isethionate salt, powder
    Pentamidine isethionate, United States Pharmacopeia (USP) Reference Standard Pentamidine isetionate Pentamidine isetionate (JAN)
    Pentamidine isothionate Pentaminide isetionate Pneumopent
    Prestwick_857 PubChem20964 Q26841221
    R.P. 2512 RP 2512 S-3112
    SCHEMBL33615 SPECTRUM1500641 SR-01000075174
    SR-01000075174-1 SR-01000075174-6 SR-01000075174-7
    ST2407516 ST51006692 TC-137331
    Tox21_110742 Tox21_110742_1 Tox21_201722
    Tox21_300312 UNII-V2P3K60DA2 USAF XR-10
    V2P3K60DA2 W-108199 WR 4931
    Z1558572531 [pentane-1,5-diylbis(oxy-4,1-phenylene)]bis(aminomethaniminium) bis(2-hydroxyethanesulfonate) bis(2-hydroxyethane-1-sulfonic acid)
    p,p'-(Pentamethylenedioxy)dibenzamidine bis(beta-hydroxyethanesulfonate) pentamidine-isethionate

    CAS Number 100-33-4, 140-64-7, 14230-00-3
    PubChem Compound 8813
    KEGG Drug D00834
    ChEBI 7977