Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
ELECTRON TRANSPORT CHAIN | rat | isolated liver mitochondria | measurements of mitochondrial respiration; RST inhibition assay, RST uncoupling assay; IC 50ratio of glucose/galactose assay | decrease | 53 | |||
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Danger |
Aggregated GHS information provided by 15 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H317 (66.67%): May cause an allergic skin reaction [Warning Sensitization, Skin] H360 (66.67%): May damage fertility or the unborn child [Danger Reproductive toxicity] H361 (33.33%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H373 (66.67%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P261, P272, P280, P281, P302+P352, P308+P313, P314, P321, P333+P313, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
(11beta,16beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione | (1R,2S,10S,11S,13S,14R,15S,17S)-1-Chloro-14-(2-glycoloyl)-14,17-dihydroxy-2,13,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one; | (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one | (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one | (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
179957-EP2272832A1 | 20528-EP2295402A2 | 20528-EP2295409A1 |
20528-EP2314585A1 | 20528-EP2314590A1 | 4419-39-0 |
8060AH | 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione | 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione (Beclometasone) |
9alpha-Chloro-11beta,17alpha,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione | 9alpha-Chloro-16beta-methyl-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione | 9alpha-Chloro-16beta-methylprednisolone |
API0001600 | AS-58067 | BCBcMAP01_000159 |
BDBM53488 | BIDD:GT0556 | BMJ 5800 |
Beclocort | Beclometason (TN) | Beclometasona |
Beclometasona [INN-Spanish] | Beclometasone | Beclometasone |
Beclometasone (INN) | Beclometasone [INN:BAN] | Beclometasone [INN] |
Beclometasone. Short expiry date due to chemical nature of component(s) | Beclometasonum | Beclometasonum [INN-Latin] |
Beclomethasone Solution | C06842 | C22H29ClO5 |
CAS-4419-39-0 | CHEBI:3001 | CHEMBL1586 |
CS-5872 | D07495 | DSSTox_CID_20750 |
DSSTox_GSID_40750 | DSSTox_RID_79587 | DTXSID5040750 |
EINECS 224-585-9 | FT-0662507 | GTPL7059 |
HMS2233A18 | HY-B1540 | KGZ1SLC28Z |
LS-174992 | MFCD00135614 | MLS000028668 |
MLS001076089 | NBMKJKDGKREAPL-DVTGEIKXSA-N | NCGC00164402-01 |
NCGC00179392-03 | Opera_ID_1081 | Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11beta,16beta)- |
SC-65670 | SCHEMBL3183 | SMP1_000039 |
SMR000058899 | SR-01000000273 | SR-01000000273-4 |
Tox21_112116 | Tox21_112116_1 | UNII-KGZ1SLC28Z |
ZINC4097285 | beclomethasone | cid_20469 |
pulvinal |