Compound

D0510 | amytal

Molecular Formula C11H18N2O3
Molecular Weight 226.27
Structure
Trade names Amobarbital, amylobarbitone, sodium amytal
Description Complex I inhibitor; barbiturate with hypnotic and sedative properties

N

N05CA02 Amobarbital


[N05CA] Barbiturates, plain


[N05C] HYPNOTICS AND SEDATIVES


[N05] PSYCHOLEPTICS


[N] Nervous system


Toxicity Dose Time Species Model Method Action Positive criterion Reference
ELECTRON TRANSPORT CHAIN affect 53
ELECTRON TRANSPORT CHAIN 0.2 mM NADH–Q-1 decrease IC50 112

Target Dose Time Species Model Method Action Positive criterion Reference
NADH:ubiquinone reductase 0.2 mM NADH–Q-1 inhibitor IC50 112
NADH:ubiquinone reductase 185
semiquinone antagonist 53

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 40 companies from 1 notifications to the ECHA C&L Inventory.


H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P264, P270, P301+P310, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 057A558 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)- 2,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-
    5-Ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione 5-Ethyl-5-(3-methylbutyl)-2,6(1H,3H,5H)-pyrimidinetrione 5-Ethyl-5-(3-methylbutyl)barbituric acid
    5-Ethyl-5-isoamylbarbituric acid 5-Ethyl-5-isoamylmalonyl urea 5-Ethyl-5-isopentyl-2,4,6(1H,3H,5H)-pyrimidinetrione #
    5-Ethyl-5-isopentylbarbituric acid 5-Ethyl-5-isopentylbarbitursaeure 5-Isoamyl-5-ethylbarbituric acid
    5-ethyl-5-(3-methylbutyl)-1,3-diazinane-2,4,6-trione 5-ethyl-5-(3-methylbutyl)pyrimidine-2,4,6(1H,3H,5H)-trione 57-43-2
    AMAL API0001485 Amasust
    Amital Amobarbital (JP17/INN) Amobarbital 0.1 mg/ml in Methanol
    Amobarbital 1.0 mg/ml in Methanol Amobarbital [INN:JAN] Amobarbital [USP:INN:BAN:JAN]
    Amobarbital solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material Amobarbital suppository dosage form Amobarbitale
    Amobarbitale [DCIT] Amobarbitalum Amobarbitalum [INN-Latin]
    Amobarbitone Amospan Amybal
    Amylbarbitone Amylobarbital Amylobarbitone
    Amylobarbitone|||Amytal|||5-Ethyl-5-isoamylbarbituric acid Amytal BIDD:PXR0091
    Barbamil Barbamyl Barbamyl acid
    Barbituric acid, 5-ethyl-5-isoamyl- Barbituric acid, 5-ethyl-5-isopentyl- Binoctal
    C07536 CAS-57-43-2 CBDivE_006514
    CCRIS 5454 CHEBI:2673 CHEMBL267894
    D00555 DB01351 DEA No. 2125
    DSSTox_CID_81 DSSTox_GSID_20081 DSSTox_RID_75353
    DTXSID9020081 Dexamyl (Salt/Mix) DivK1c_000994
    Dorlotyn Dormytal EINECS 200-330-7
    Ethylisopentylbarbituric acid Eunoctal FT-0662116
    GWH6IJ239E HSDB 3286 IDI1_000994
    InChI=1/C11H18N2O3/c1-4-11(6-5-7(2)3)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16); Isoamylethylbarbituric acid Isomyl
    Isomytal Isomytal (TN) KBio1_000994
    LS-7196 Mylodorm NCGC00247711-01
    NINDS_000994 NSC 10815 NSC-10815
    NSC-120800 NSC-32406 NSC10815
    NSC120800 NSC32406 Oprea1_587446
    Pentymal Pentymalum Q415850
    Robarb SCHEMBL15364946 SCHEMBL43780
    Schiwanox Sednotic Somnal
    Stadadorm Sumital Talamo
    Tox21_112866 UNII-GWH6IJ239E VIROVYVQCGLCII-UHFFFAOYSA-
    VIROVYVQCGLCII-UHFFFAOYSA-N WLN: T6VMVMV FHJ F2 F2Y1&1 ZINC4811698
    amobarbital component of 15-90 component of 15-90 (Salt/Mix)
    component of Amo-Dextrosule component of Amo-Dextrosule (Salt/Mix) component of Dexamyl
    component of Dexamyl (Salt/Mix) component of Q-Caps component of Q-Caps (Salt/Mix)

    CAS Number 57-43-2
    PubChem Compound 2164
    ChEBI 2673