Drug

D0552 | nitric oxide

Molecular Formula NO
Molecular Weight 30.006
Structure
State liquid
Route of elimination Nitrate has been identified as the predominant nitric oxide metabolite excreted in the urine, accounting for >70% of the nitric oxide dose inhaled.
Half life 2–6 seconds
Absorption Nitric oxide is absorbed systemically after inhalation.

R

R07AX01 Nitric oxide


[R07AX] Other respiratory system products


[R07A] OTHER RESPIRATORY SYSTEM PRODUCTS


[R07] OTHER RESPIRATORY SYSTEM PRODUCTS


[R] Respiratory system


Toxicity Dose Time Species Model Method Action Positive criterion Reference
ELECTRON TRANSPORT CHAIN affect 167

Target Dose Time Species Model Method Action Positive criterion Reference
oxygen competitive inhibitor 167

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 276 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H270 (100%): May cause or intensify fire


oxidizer [Danger Oxidizing gases]


H280 (86.23%): Contains gas under pressure


may explode if heated [Warning Gases under pressure]


H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]


H318 (32.25%): Causes serious eye damage [Danger Serious eye damage/eye irritation]


H330 (86.23%): Fatal if inhaled [Danger Acute toxicity, inhalation]


H331 (13.77%): Toxic if inhaled [Danger Acute toxicity, inhalation]


H373 (30.07%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P220, P244, P260, P261, P264, P271, P280, P284, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P311, P314, P320, P321, P363, P370+P376, P403, P403+P233, P405, P410+P403, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H270: May cause or intensify fire


oxidizer [Danger Oxidizing gases]


H280: Contains gas under pressure


may explode if heated [Warning Gases under pressure]


H330: Fatal if inhaled [Danger Acute toxicity, inhalation]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


P220, P244, P260, P264, P270, P271, P284, P304+P340, P307+P311, P310, P320, P321, P370+P376, P403, P403+P233, P405, P410+P403, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H270: May cause or intensify fire


oxidizer [Danger Oxidizing gases]


H280: Contains gas under pressure


may explode if heated [Warning Gases under pressure]


H331: Toxic if inhaled [Danger Acute toxicity, inhalation]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


P220, P244, P260, P261, P264, P270, P271, P304+P340, P307+P311, P311, P321, P370+P376, P403, P403+P233, P405, P410+P403, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (.)NO (NO)(.) 10102-43-9
    C00533 CHEBI:16480 CHEMBL1200689
    CTK0H7679 D00074; DB00435
    DTXSID1020938 EDRF HOA
    INOmax (TN) Mononitrogen monoxide NO(.)
    Nitric oxide (JAN) Nitric oxide, 98.5% Nitrosoradical
    OHM 11771 Stickstoff(II)-oxid Stickstoffmonoxid
    [NO] endothelium-derived relaxing factor monoxido de nitrogeno
    monoxyde d'azote nitric oxide nitrogen monooxide
    nitrogen monoxide nitrosyl oxido de nitrogeno(II)
    oxido nitrico oxidonitrogen(.) oxoazanyl
    oxyde azotique

    DrugBank Name nitric oxide
    DrugBank DB00435
    CAS Number 10102-43-9, 11104-93-1
    PubChem Compound 145068
    KEGG Compound ID C00533
    KEGG Drug D00074
    ChEBI 16480