D0582 | 1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 30.64±18.87 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 28.18 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Warning |
Aggregated GHS information provided by 1752 companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (99.83%): Harmful if swallowed [Warning Acute toxicity, oral] H400 (93.09%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P273, P301+P312, P330, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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Warning |
Aggregated GHS information provided by 355 companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 5 of 355 companies. For more detailed information, please visit ECHA C&L website Of the 12 notification(s) provided by 350 of 355 companies with hazard statement code(s): H302 (99.43%): Harmful if swallowed [Warning Acute toxicity, oral] H400 (88.57%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (99.14%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P273, P301+P312, P330, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P260, P264, P270, P273, P280, P301+P312, P305+P351+P338, P314, P330, P337+P313, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| (+/-)-1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydro-2-naphthalenyl)-1-ethanone | 1,1,3,4,4,6-Hexamethyl-7-acetyl-1,2,3,4-tetrahydronaphthalene | 1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydro-2-naphthalenyl)ethanone # |
| 1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)ethanone | 1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-one | 1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone |
| 1-(3,5,5,6,8,8-hexamethyl-6,7-dihydronaphthalen-2-yl)ethanone | 1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)ethan- one | 1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one |
| 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)-ethanone | 145T777 | 1506-02-1 |
| 2'-Acetonaphthone, 5',6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl- | 2'-Acetonaphthone, 5',6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl- (VAN) | 2'-Acetonaphthone, 5',6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl- (VAN) (8CI) |
| 2'-Acetonaphthone,6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl- | 2-Acetyl-3,5,5,6,8,8-hexamethyl-5,6,7,8- tetrahydronaphthalene | 21145-77-7 |
| 4CH-007834 | 6-Acetyl-1,1,2,4,4,7-hexamethyl-1,2,3,4-tetrahydronaphthalene | 6-Acetyl-1,1,2,4,4,7-hexamethyltetralin |
| 6-Acetyl-1,1,2,4,4,7-hexamethyltetralin, >=98% | 6-Acetyl-1,1,2,4,4,7-hexamethyltetralin, AldrichCPR | 6-Acetyl-1,1,2,4,4,7-hexamethyltetralin, analytical standard |
| 6-acetyl-1,1,2,4,4,7-hexamethyltetraline | 7-Acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene | 7-Acetyl-1,1,3,4,4,6-hexamethyl-tetra-hydronaphtalene |
| 7-Acetyl-1,1,3,4,4,6-hexamethyltetrahydronaphthalene | 7-Acetyl-1,1,3,4,4,6-hexamethyltetralin | 7-Acetyl-1,3,4,4,6-hexamethyltetrahydronaphthalene |
| AHMT | AHMT (perfume) | AHTN |
| AHTN (Tonalide) | AHTN 10 microg/mL in Cyclohexane | AI3-28517 |
| AK-72913 | AKOS015920154 | AX8157828 |
| Acetyl hexamethyl tetralin | BBL018868 | BR-72913 |
| CAS-21145-77-7 | CCRIS 8403 | CCRIS 8496 |
| CHEBI:88666 | CHEMBL3184267 | CTK3J2140 |
| DNRJTBAOUJJKDY-UHFFFAOYSA-N | DSSTox_CID_21544 | DSSTox_GSID_41544 |
| DSSTox_RID_79772 | DTXSID7041544 | EC 216-133-4 |
| EC 244-240-6 | EINECS 216-133-4 | EINECS 244-240-6 |
| Ethanone, 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)- | Ethanone, 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)- (VAN) | Ethanone, 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)- (VAN) (9CI); |
| Ethanone,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)- (VA | FT-0675293 | FT-0688135 |
| GS-4166 | HSDB 7515 | KS-00000HC4 |
| KS-00000ZD4 | KSC492C4B | LS-67597 |
| LS-67598 | MCULE-5128561438 | Musk tonalid |
| NCGC00255431-01 | NSC 19550 | NSC-19550 |
| NSC19550 | Q2409972 | RT-000301 |
| S-5529 | SCHEMBL110818 | ST24026857 |
| STL195398 | TR-009939 | Tentarome |
| Tetralide | Tonalid | Tonalide |
| Tox21_301256 | W-107569 | W-109114 |
| W4412 | acetyl methyl tetramethyl tetralin | fixolide |