D0583 | 1,1,1-trichloropropanone
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 1.22±0.56 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 3.16 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 23.74±29.59 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Warning |
Aggregated GHS information provided by 44 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 3 of 44 companies. For more detailed information, please visit ECHA C&L website Of the 4 notification(s) provided by 41 of 44 companies with hazard statement code(s): H315 (97.56%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (97.56%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (95.12%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| .alpha.,.alpha.,.alpha.-Trichloroacetone | .alpha.,.alpha.-Trichloroacetone | 1,1,1-TRICHLOROACETONE |
| 1,1,1-TRICHLOROACETONE 95+% | 1,1,1-Trichloro-2-propanone | 1,1,1-Trichloropropanone |
| 1,1,1-trichloro-propan-2-one | 1,1,1-trichloropropan-2-one | 1,1-Trichloro-2-propanone |
| 1,1-Trichloroacetone | 1,1-Trichloropropanone | 2-Propanone, 1,1,1-trichloro- |
| 2-Propanone, trichloro- | 2-Propanone,1,1-trichloro- | 72497-18-8 |
| 918-00-3 | ACMC-209rdn | AI3-19851 |
| AKOS015848746 | ANW-39753 | BRN 1748883 |
| CAS-918-00-3 | CCRIS 7196 | CCl3COCH3 |
| CHEMBL3185648 | CTK2H9253 | DB-057269 |
| DSSTox_CID_1679 | DSSTox_GSID_21679 | DSSTox_RID_76279 |
| DTXSID5021679 | FT-0605937 | HSDB 7625 |
| InChI=1/C3H3Cl3O/c1-2(7)3(4,5)6/h1H | LS-123195 | MCULE-6100811363 |
| NCGC00248963-01 | NCGC00258774-01 | NSC 2645 |
| NSC-2645 | NSC2645 | NW27ZG5LDA |
| Q27285080; | SCHEMBL136756 | SMZHKGXSEAGRTI-UHFFFAOYSA-N |
| TR-028911 | Tox21_201222 | Trichloroacetone |
| UNII-NW27ZG5LDA | ZINC1641054 | alpha,alpha,alpha-Trichloroacetone |
| CAS Number | 72497-18-8, 918-00-3 |
| PubChem Compound | 13514 |