D0594 | 1,4-benzenediamine
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 3.28±0.42 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 2.18 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H331: Toxic if inhaled [Danger Acute toxicity, inhalation] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P311, P312, P321, P322, P330, P333+P313, P337+P313, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Danger |
Aggregated GHS information provided by 553 companies from 24 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301+H311+H331 (14.83%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral acute toxicity, dermal acute toxicity, inhalation] H301 (99.82%): Toxic if swallowed [Danger Acute toxicity, oral] H311 (99.82%): Toxic in contact with skin [Danger Acute toxicity, dermal] H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin] H319 (99.82%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H331 (99.82%): Toxic if inhaled [Danger Acute toxicity, inhalation] H370 (11.75%): Causes damage to organs [Danger Specific target organ toxicity, single exposure] H400 (92.59%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (99.82%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P260, P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P307+P311, P311, P312, P321, P322, P330, P333+P313, P337+P313, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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|
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H331: Toxic if inhaled [Danger Acute toxicity, inhalation] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P311, P312, P321, P322, P330, P333+P313, P337+P313, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H315: Causes skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H320: Causes eye irritation [Warning Serious eye damage/eye irritation] H331: Toxic if inhaled [Danger Acute toxicity, inhalation] H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P260, P261, P264, P270, P271, P272, P280, P285, P301+P310, P302+P352, P304+P340, P304+P341, P305+P351+P338, P307+P311, P311, P314, P321, P330, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H315: Causes skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H333: May be harmful if inhaled [Warning Acute toxicity, inhalation] H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P260, P261, P264, P270, P271, P272, P280, P285, P301+P310, P302+P352, P304+P312, P304+P340, P304+P341, P305+P351+P338, P307+P311, P310, P312, P314, P321, P330, P332+P313, P333+P313, P342+P311, P362, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H320: Causes eye irritation [Warning Serious eye damage/eye irritation] H331: Toxic if inhaled [Danger Acute toxicity, inhalation] H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P260, P261, P264, P270, P271, P272, P273, P280, P285, P301+P310, P302+P352, P304+P340, P304+P341, P305+P351+P338, P307+P311, P311, P314, P321, P330, P333+P313, P337+P313, P342+P311, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| 1,4 phenylene diamine | 1,4-BENZENEDIAMINE | 1,4-Benzenediamine |
| 1,4-DIAMINO-BENZENE | 1,4-Diaminobenzene | 1,4-Diaminobenzene |
| 1,4-Phenylenediamine | 1,4-Phenylenediamine | 1,4-Phenylenediamine 1000 microg/mL in Acetonitrile |
| 1,4-Phenylenediamine 2000 microg/mL in Acetonitrile | 1,4-Phenylenediamine-13N2 | 1,4-diamino benzene |
| 106-50-3 | 4-Aminoaniline | 4-Phenylenediamine |
| 4-amino-aniline | 4-aminophenylamine | 4-phenylene diamine |
| AB1002877 | ACMC-1CUCB | ACT07286 |
| AI3-00710 | AKOS005716327 | ANW-15356 |
| AS00466 | ATTERCOP-CHM AT126215 | Aminogen II |
| BASF ursol D | BBL011602 | Benzofur D |
| C.I. 76060 | C.I. 76076 (Salt/Mix) | C.I. Developer 13 |
| C.I. Oxidation Base 10 | C19499 | CAS-106-50-3 |
| CBCKQZAAMUWICA-UHFFFAOYSA-N | CCRIS 509 | CHEBI:51403 |
| CHEMBL403741 | CI 76060 | CI Developer 13 |
| CI Oxidation Base 10 | CTK0H4606 | DB14141 |
| DSSTox_CID_1138 | DSSTox_GSID_21138 | DSSTox_RID_75969 |
| DTXSID9021138 | Developer 13 | Developer PF |
| Durafur Black R | EC 203-404-7 | EINECS 203-404-7 |
| EN300-19064 | Epitope ID:114080 | F0001-0125 |
| FT-0606928 | FUR Brown 41866 | Fenylenodwuamina |
| Fenylenodwuamina [Polish] | Fouramine D | Fourrine 1 |
| Fourrine D | Fur Black 41866 | Fur Black 41867 |
| Fur Yellow | Furro D | Futramine D |
| HSDB 2518 | HSDB 6256 (Salt/Mix) | I809 |
| InChI=1/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H | JAROCOL PPD | KS-00000V64 |
| KSC174M0N | LABOTEST-BB LTBB002107 | LS-402 |
| MCULE-9588027148 | MFCD00007901 | NCGC00159375-02 |
| NCGC00159375-03 | NCGC00159375-04 | NCGC00159375-05 |
| NCGC00256482-01 | NCGC00259542-01 | NE10526 |
| NSC 4777 | NSC-4777 | NSC4777 |
| Nako H | OTAVA-BB 1509975 | Orsin |
| Oxidation base 10 | P-PHENYLENE DIAMINE | P0170 |
| PARA PHENYLENE DIAMINE | PHENYLENEDIAMINE, P- | Paraphenylen-diamine |
| Paraphenylenediamine | Pelagol D | Pelagol DR |
| Pelagol Grey D | Peltol D | Phenylenediamine, para |
| Phenylenediamine, para- | Phenylenediamines | PubChem22180 |
| Q415024 | RTR-013269 | Renal PF |
| Rodol D | SC-77433 | SCHEMBL27981 |
| ST2419110 | STL163334 | STR01091 |
| Santoflex IC | Santoflex LC | TRA0038404 |
| Tertral D | Tox21_111615 | Tox21_111615_1 |
| Tox21_201993 | Tox21_302943 | U770QIT64J |
| UN 1673 | UNII-TJX894Z2PK component CBCKQZAAMUWICA-UHFFFAOYSA-N | UNII-U770QIT64J |
| Ursol D | Usaf ek-394 | WLN: ZR DZ |
| Z426537038 | ZINC8294962 | Zoba Black D |
| benzene-1,4-diamine | p-Aminoaniline | p-Benzenediamine |
| p-Diaminobenzene | p-Fenylendiamin | p-Fenylendiamin [Czech] |
| p-Phenyldiamine | p-Phenylenediamine | p-Phenylenediamine [UN1673] [Keep away from food] |
| p-Phenylenediamine [UN1673] [Keep away from food] | p-Phenylenediamine, 99+% | p-Phenylenediamine, >=99.0% (GC/NT) |
| p-Phenylenediamine, flakes, >=99.5% | p-Phenylenediamine, sublimed, >=99% | p-Phenylenediamine, technical, >=97.0% (GC/NT) |
| p-Phenylenediamine, zone-refined, purified by sublimation, >=99%; | p-phenylendiamine | p-phenylene-diamine |
| p-phenylenediamine base | para-diaminobenzene | para-phenylene diamine |
| para-phenylenediamine | paraphenylene diamine | paraphenylene-diamine |