Compound
D0601 | 17alpha-ethinylestradiol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 19.12±5.99 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 15.45 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 18.39±1.50 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
   |
Danger |
Aggregated GHS information provided by 127 companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (50.39%): Harmful if swallowed [Warning Acute toxicity, oral] H350 (77.17%): May cause cancer [Danger Carcinogenicity] H351 (19.69%): Suspected of causing cancer [Warning Carcinogenicity] H360 (66.93%): May damage fertility or the unborn child [Danger Reproductive toxicity] H362 (19.69%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation] H372 (41.73%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400 (21.26%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (64.57%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P263, P264, P270, P273, P281, P301+P312, P308+P313, P314, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| (17-alpha)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17,diol | (17alpha)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol | (17beta)-17-ethynylestra-1(10),2,4-triene-3,17-diol |
| (17beta)-17-ethynylestra-1,3,5(10)-triene-3,17-diol | (1S,10R,11S,14R,15S)-14-ethynyl-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol | (1S,11S,15S,10R,14R)-14-ethynyl-15-methyltetracyclo[8.7.0.0<2,7>.0<11,15>]hept adeca-2(7),3,5-triene-5,14-diol |
| (1S,11S,15S,10R,14R)-14-ethynyl-15-methyltetracyclo[8.7.0.0<2,7>.0<11,15>]hept adeca-2,4,6-triene-5,14-diol; | (8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol | (8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol |
| (9beta,13alpha,14beta,17alpha)-17-ethynylestra-1(10),2,4-triene-3,17-diol | 003E690 | 17 alpha Ethynylestradiol |
| 17 alpha-ethinyestradiol | 17-Ethinyl-3,17-estradiol | 17-Ethinyl-3,17-oestradiol |
| 17-Ethinylestradiol | 17-Ethynyl-3,17-dihydroxy-1,3,5-oestratriene | 17-Ethynyl-3-17-dihydroxy-1,3,5-oestratriene |
| 17-Ethynyl-3-17-dihydroxy-1,5-oestratriene | 17-Ethynylestra-1,3,5(10)-triene-3,17beta-diol | 17-Ethynylestradiol |
| 17-Ethynylestradiol ram | 17-Ethynyloestra-1,3,5(10)-triene-3,17.beta.-diol | 17-Ethynyloestra-1,5(10)-triene-3,17.beta.-diol |
| 17-Ethynyloestradiol | 17-alpha-Ethinyl-17-beta-estradiol | 17-alpha-Ethinyl-3,17-dihydroxy-delta(sup 1,3,5)-estratriene |
| 17-alpha-Ethinyl-delta(sup 1,3,5(10))oestratriene-3,17-beta-diol | 17-alpha-Ethinylestra-1,3,5(10)-triene-3,17-beta-diol | 17-alpha-Ethinyloestra-1,3,5(10)-triene-3,17-beta-diol |
| 17-alpha-Ethynyl-1,3,5(10)-estratriene-3,17-beta-diol | 17-alpha-Ethynyl-1,3,5(10)-oestratriene-3,17-beta-diol | 17-alpha-Ethynyl-1,3,5-oestratriene-3,17-beta-diol |
| 17-alpha-Ethynyl-17-beta-oestradiol | 17-alpha-Ethynylestradiol | 17-alpha-Ethynylestradiol-17-beta |
| 17-alpha-ethynyl estradiol | 17.alpha.-Ethinyl-1,3,5(10)-estratriene-3,17-diol | 17.alpha.-Ethinyl-17.beta.-estradiol |
| 17.alpha.-Ethinyl-3,17-dihydroxy-.delta.(sup1,3,5)-estratriene | 17.alpha.-Ethinyl-3,3,5)-estratriene | 17.alpha.-Ethinylestradiol |
| 17.alpha.-Ethynyl-1,3,5(10)-estratriene-3,17.beta.-diol | 17.alpha.-Ethynyl-1,3,5(10)-oestratriene-3,17.beta.-diol | 17.alpha.-Ethynyl-1,5-estratriene-3,17.beta.-diol |
| 17.alpha.-Ethynyl-1,5-oestratriene-3,17.beta.-diol | 17.alpha.-Ethynyl-17.beta.-oestradiol | 17.alpha.-Ethynylestra-1,3,5(10)-triene-3,17.beta.-diol |
| 17.alpha.-Ethynylestra-1,5(10)-triene-3,17.beta.-diol | 17.alpha.-Ethynylestradiol | 17.alpha.-Ethynylestradiol-l7.beta. |
| 17.alpha.-Ethynyloestra-1,3,5(10)-triene-3,17.beta.-diol | 17.alpha.-Ethynyloestra-1,5(10)-triene-3,17.beta.-diol | 17.alpha.-Ethynyloestradiol |
| 17.alpha.-Ethynyloestradiol-17.beta. | 17.alpha.-ethinyl-.delta.(sup1,3,5(10))oestratriene-3,17-.beta. -diol | 17.alpha.-ethinyl-.delta.(sup1,5(10))oestratriene-3,17-.beta.-diol |
| 17.alpha.-ethinyl-3,17-dihydroxy-.delta.(sup1,3,5)oestratriene | 17.alpha.-ethinyl-3,3,5)oestratriene | 17.alpha.-ethinylestra-1,3,5(10)-triene-3,17.beta.-diol |
| 17.alpha.-ethinylestra-1,5(10)-triene-3,17.beta.-diol | 17.alpha.-ethinyloestra-1,3,5(10)-triene-3,17.beta.-diol | 17.alpha.-ethinyloestra-1,5(10)-triene-3,17.beta.-diol |
| 17.beta.-Estradiol, 17-ethynyl- | 17a-Ethinyl-17b-estradiol | 17a-Ethinylestradiol |
| 17a-Ethinylestradiol 100 microg/mL in Acetonitrile | 17a-Ethynyl-17b-oestradiol | 17a-Ethynylestradiol |
| 17a-Ethynylestradiol-l7b | 17a-Ethynyloestradiol | 17a-Ethynyloestradiol-17b |
| 17alpha-Ethinyl estradiol | 17alpha-Ethinyl-1,3,5(10)-estratriene-3,17-diol | 17alpha-Ethinyl-17beta-estradiol |
| 17alpha-Ethinyl-3,17-dihydroxy-delta(sup1,3,5)-estratriene | 17alpha-Ethinylestradiol | 17alpha-Ethinylestradiol-17beta |
| 17alpha-Ethynyl-1,3,5(10)-estratriene-3,17beta-diol | 17alpha-Ethynylestra-1,3,5(10)-triene-3,17beta-diol | 17alpha-Ethynylestradiol |
| 17alpha-Ethynylestradiol, >=98% | 17alpha-Ethynylestradiol, >=98.0% (HPLC) | 17alpha-Ethynylestradiol, VETRANAL(TM), analytical standard |
| 17alpha-Ethynyloestradiol | 17alpha-Ethynyloestradiol-17beta | 17alpha-ethinyl-3,17-dihydroxy-delta(sup1,3,5)oestratriene |
| 17alpha-ethinyl-delta(sup1,3,5(10))oestratriene-3,17-beta -diol | 17alpha-ethinyl-estra-1,3,5(10)-triene-3,17beta-diol | 17alpha-ethinylestra-1,3,5(10)-triene-3,17beta-diol |
| 17alpha-ethinyloestra-1,3,5(10)-triene-3,17beta-diol | 17beta-Estradiol, 17-ethynyl- | 17|A-Ethynylestradiol |
| 17|A-Ethynylestradiol;Ethynylestradiol | 19-Nor-1,3,5(10),17alpha-pregnatrien-20-yne-3,17-diol | 19-Nor-17-alpha-pregna-1,3,5(10)-trien-20-yne-3,17-diol |
| 19-Nor-17-alpha-pregna-1,3,5(10)-triene-20-yne-3,17-diol | 19-Nor-17.alpha.-pregna-1,3,5(10)-trien-20-yn-3,17-diol | 19-Nor-17.alpha.-pregna-1,3,5(10)-trien-20-yne-3,17-diol |
| 19-Nor-17.alpha.-pregna-1,3,5(10)-trien-20-yne-3,17.beta.-diol | 19-Nor-17.alpha.-pregna-1,5(10)-trien-20-yne-3,17-diol | 19-Nor-17.alpha.-pregna-1,5[10]-trien-20-yne-3,17-diol |
| 19-Nor-17alpha-pregna-1,3,5(10)-trien-20-yne-3,17-diol | 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol | 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17.alpha.)- |
| 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17a)- | 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)- | 19-Norpregna-1,5(10)-trien-20-yne-3,17-diol, (17.alpha.)- |
| 19-nor-17.alpha.-Pregna-1,5(10)-trien-2-yne-3,17-diol | 3,17-beta-Dihydroxy-17-alpha-ethynyl-1,3,5(10)-estratriene | 3,17-beta-Dihydroxy-17-alpha-ethynyl-1,3,5(10)-oestratriene |
| 3,17.beta.-Dihydroxy-17.alpha.-ethynyl-1,3,5(10)-estratriene | 3,17.beta.-Dihydroxy-17.alpha.-ethynyl-1,3,5(10)-oestratriene | 3,17beta-Dihydroxy-17alpha-ethynyl-1,3,5(10)-estratriene |
| 3,17beta-Dihydroxy-17alpha-ethynyl-1,3,5(10)-oestratriene | 392-EP2270017A1 | 392-EP2272846A1 |
| 392-EP2275422A1 | 392-EP2277622A1 | 392-EP2281816A1 |
| 392-EP2308866A1 | 392-EP2372017A1 | 392-EP2374791A1 |
| 3WF | 423D2T571U | 57-63-6 |
| AB00441335-11 | AB00441335_12 | AB2000171 |
| AC-2169 | AI3-52941 | AKOS015894925 |
| Aethinyloestradiolum | Aethinyoestradiol | Aethinyoestradiol [German] |
| Amenoron | Amenorone | Anovlar |
| Anovlar (Salt/Mix) | BDBM50187243 | BFPYWIDHMRZLRN-SLHNCBLASA-N |
| BIDD:ER0162 | BRD-K48195008-001-19-9 | BRN 2419975 |
| C07534 | CAS-57-63-6 | CCG-100819 |
| CCRIS 286 | CHEBI:4903 | CHEMBL691 |
| CS-2161 | Certified Reference Material | Certostat |
| Chee-O-Gen | Chee-O-Genf | D00554 |
| DB00977 | DSSTox_CID_576 | DSSTox_GSID_20576 |
| DSSTox_RID_75668 | DTXSID5020576 | Desogen (Salt/Mix) |
| Diognat-E | Diogyn E | Diogyn-E |
| Diprol | Dyloform | EE |
| EE(sub 2) | EE2 | EINECS 200-342-2 |
| EN300-119516 | ENDOCRINE DISRUPTOR (ETHINYL ESTRADIOL) (SEE ALSO ETHINYL ESTRADIOL (57-63-6)) | EO |
| ETHINYLESTRADIOL | Ertonyl | Esteed |
| Estigyn | Estinyl | Estinyl (TN) |
| Eston-E | Estopherol | Estopherol (Salt/Mix) |
| Estoral | Estoral (Orion) | Estoral (VAN) |
| Estoral [Orion] | Estoral {[Orion]} | Estorals |
| Estra-1,3,5(10)-triene-3,17-beta-diol, 17-alpha-ethynyl- | Estra-1,3,5(10)-triene-3,17.beta.-diol, 17.alpha.-ethynyl- | Estra-1,3,5(10)-triene-3,17beta-diol, 17alpha-ethynyl- |
| Estra-1,5(10)-triene-3,17.beta.-diol, 17-ethynyl- | Estra-1,5(10)-triene-3,17.beta.-diol, 17.alpha.-ethynyl- | Estra-1,5[10]-triene-3,17.beta.-diol, 17-ethynyl- |
| Estradiol, 17-ethynyl- | Ethidol | Ethinoral |
| Ethinyl E2 | Ethinyl Estradiol [USP] | Ethinyl Estradiol, Pharmaceutical Secondary Standard |
| Ethinyl estradiol (USP) | Ethinyl estradiol, United States Pharmacopeia (USP) Reference Standard | Ethinyl-oestranol |
| Ethinylestradiol (JP17/INN) | Ethinylestradiol [INN:BAN:JAN] | Ethinylestradiol for system suitability, European Pharmacopoeia (EP) Reference Standard |
| Ethinylestradiol, 98% | Ethinylestradiol, European Pharmacopoeia (EP) Reference Standard | Ethinylestradiolum |
| Ethinylestradiolum [INN-Latin] | Ethinylestriol | Ethinyloestradiol |
| Ethinyloestradiol [Steroidal oestrogens] | Ethynyl estradiol | Ethynylestradiol |
| Ethynyloestradiol | Eticyclin | Eticyclol |
| Eticylol | Etinestrol | Etinestryl |
| Etinilestradiol | Etinilestradiol [INN-Spanish] | Etinilestradiolo |
| Etinilestradiolo [DCIT] | Etinoestryl | Etistradiol |
| Etivex | FT-0625736 | Feminone |
| Follicoral | GTPL7071 | Ginestrene |
| HMS2051I19 | HMS2235J09 | HMS3715J09 |
| HSDB 3587 | HY-B0216 | Inestra |
| KS-5257 | Kolpolyn | LMST02010036 |
| LS-231 | Levlen (Salt/Mix) | Linoral |
| Lynoral | MCULE-5991854877 | MFCD00003690 |
| MLS000028479 | MLS000758274 | MLS001424011 |
| Menolyn | Microfollin | Microfollin Forte |
| NC00069 | NCGC00091533-01 | NCGC00091533-04 |
| NCGC00091533-05 | NCGC00091533-07 | NCGC00091533-08 |
| NCGC00091533-09 | NCGC00091533-10 | NCGC00254514-01 |
| NCGC00258843-01 | NCI60_000234 | NSC-10973 |
| NSC10973 | Neo-Estrone | Nogest-S |
| Nordette (Salt/Mix) | Norinyl | Novestrol |
| OVULEN-21 | OVULEN-28 | Opera_ID_1808 |
| Oracon (Salt/Mix) | Oradiol | Orestralyn |
| Orestrayln | Ortho Evra (Salt/Mix) | Ortho-Cyclen (Salt/Mix) |
| Ortrel (Salt/Mix) | PUBERTAL ETHINYL ESTRADIOL STUDY | Palonyl |
| Perovex | Primogyn | Primogyn C |
| Primogyn M | Progynon C | Progynon M |
| Prosexol | Q-201076 | Q415563 |
| SBB066068 | SCHEMBL4071 | SGCUT00127 |
| SMR000058319 | SR-01000721903 | SR-01000721903-3 |
| ST081364 | Seasonale (Salt/Mix) | Seasonique (Salt/Mix) |
| Secrovin (Salt/Mix) | Spanestrin | TRANSGENIC MODEL EVALUATION (ETHINYL ESTRADIOL) |
| Tox21_111147 | Tox21_111147_1 | Tox21_201291 |
| Tox21_300413 | Tri-Levlen (Salt/Mix) | Triphasil (Salt/Mix) |
| UNII-423D2T571U | WLN: L E5 B666TTT&J E1 FQ F1UU1 OQ | Ylestol |
| Ylestrol | Z1541638513 | ZINC3812897 |
| component of Demulen | component of Oracon | component of Ortrel |
| component of Ovral | ethinyl estradiol | ethinyl-estradiol |
| ethynyl-estradiol | s1625 | to_000048 |