Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 49.48±9.45 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 25.12 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Danger |
Aggregated GHS information provided by 307 companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 3 of 307 companies. For more detailed information, please visit ECHA C&L website Of the 11 notification(s) provided by 304 of 307 companies with hazard statement code(s): H302 (89.14%): Harmful if swallowed [Warning Acute toxicity, oral] H312 (59.21%): Harmful in contact with skin [Warning Acute toxicity, dermal] H314 (89.14%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H318 (46.71%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H332 (59.21%): Harmful if inhaled [Warning Acute toxicity, inhalation] H411 (43.75%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P260, P261, P264, P270, P271, P273, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure Narcotic effects] H401: Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard] H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] |
P260, P261, P264, P270, P271, P273, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] |
P260, P264, P270, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P309+P311, P310, P321, P330, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] |
P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
(R)-2-sec-butylphenol | 2-(1-METHYLPROPYL)PHENOL | 2-(2-Butyl)phenol |
2-(butan-2-yl)phenol | 2-(methylpropyl)phenol | 2-(sec-Butyl)phenol |
2-Sec. butylphenol | 2-s-butylphenol | 2-sec-Butylphenol |
2-sec-Butylphenol, 98% | 2-sec.Butylfenol | 2-sec.Butylfenol [Czech] |
3-06-00-01852 (Beilstein Handbook Reference) | 53466-96-9 | 89-72-5 |
ACMC-209r2m | AKOS000120753 | ANW-39356 |
B0732 | BDBM50410500 | BRN 1210026 |
C14138 | CAS-89-72-5 | CCRIS 6218 |
CHEBI:34303 | CHEMBL30193 | CTK3J2919 |
DSSTox_CID_2331 | DSSTox_GSID_22331 | DSSTox_RID_76551 |
DTXSID2022331 | EC 201-933-8 | EINECS 201-933-8 |
F0001-2199; | FT-0613410 | HMS3039C13 |
HSDB 5266 | Isopropyl o-cresol | KS-00000V8H |
LS-1899 | MCULE-1162869855 | MFCD00002225 |
MLS001055345 | NCGC00090979-01 | NCGC00090979-02 |
NCGC00090979-03 | NCGC00090979-04 | NCGC00090979-05 |
NCGC00254042-01 | NCGC00258923-01 | NGFPWHGISWUQOI-UHFFFAOYSA-N |
Phenol, 2-(1-methylpropyl)- | Phenol, 2-methyl(1-methylethyl)- | Phenol, o-sec-butyl- |
Q20156241 | Q27115978 | RTR-028159 |
S653 | SBB061123 | SCHEMBL282162 |
SCHEMBL8988151 | SGCUT00117 | SMR000673564 |
ST50824243 | TR-028159 | Tox21_201372 |
Tox21_300047 | W-100361 | o-sec-Butylphenol |
o-sec.-butylphenol | ortho-sec-butylphenol | sec-butylphenol |
to_000028 |