Compound

D0648 | 2,4-di-tert-butylphenol

Molecular Formula C14H22O
Molecular Weight 206.32
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 3.50±0.73 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 3.98 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 24.04±16.59 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 1607 companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


Reported as not meeting GHS hazard criteria by 19 of 1607 companies. For more detailed information, please visit ECHA C&L website


Of the 22 notification(s) provided by 1588 of 1607 companies with hazard statement code(s):


H302 (54.97%): Harmful if swallowed [Warning Acute toxicity, oral]


H315 (92.07%): Causes skin irritation [Warning Skin corrosion/irritation]


H318 (61.59%): Causes serious eye damage [Danger Serious eye damage/eye irritation]


H319 (30.48%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335 (20.59%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


H400 (68.77%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (75.13%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H315: Causes skin irritation [Warning Skin corrosion/irritation]


H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P264, P273, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P362, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H315: Causes skin irritation [Warning Skin corrosion/irritation]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P260, P264, P270, P273, P280, P301+P312, P302+P352, P305+P351+P338, P309+P311, P314, P321, P330, P332+P313, P337+P313, P362, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H315: Causes skin irritation [Warning Skin corrosion/irritation]


H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P260, P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P309+P311, P314, P321, P330, P332+P313, P337+P313, P362, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (2S)-N-[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-1-[[(1S)-4-amino-1-[(2S)-2-[(2-amino-2-oxo-ethyl)carbamoyl]pyrrolidine-1-carbonyl]-4-oxo-butyl]carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-1-(hydro 1-Hydroxy-2,4-di-tert-butylbenzene 2,4-Ditert-Butyl-Phenol
    2,4-Bis(1,1-dimethylethyl)phenol 2,4-DI-T-BUTYLPHENOL 2,4-DTBP
    2,4-Di-tert-butylhydroxybenzene 2,4-Di-tert-butylphenol 2,4-Di-tert-butylphenol, 97%
    2,4-Di-tert-butylphenol, 99% 2,4-Di-tert.-butylphenol 2,4-Di-tertbutyl-phenol
    2,4-bis(tert-butyl)phenol 2,4-di-t-butyl-phenol 2,4-di-tert-butyl phenol
    2,4-di-tert.butylphenol 2,4-di-tertbutyl phenol 2,4-di-tertbutylphenol
    2,4-ditert-butyl phenol 2,4-ditert-butyl-phenol 2,4-ditert-butylphenol
    2,4-ditertbutylphenol 2,4-ditertiary-butyl phenol 2,4-ditertiarybutylphenol
    2,4di-tert-butylphenol 24-Ditert-Butyl-Phenol 96-76-4
    ACMC-209s7n AKOS003669719 ANW-40833
    AS-13983 Antioxidant No. 33 BCP24012
    BDBM50409544 BRN 1910383 CAS-96-76-4
    CHEBI:89188 CHEMBL29873 CTK3J0546
    D0229 DSSTox_CID_6602 DSSTox_GSID_26602
    DSSTox_RID_78158 DTXSID2026602 EC 202-532-0
    EINECS 202-532-0 F0001-2302 FOB94G6HZT
    FT-0610222 ICKWICRCANNIBI-UHFFFAOYSA-N InChI=1/C14H22O/c1-13(2,3)10-7-8-12(15)11(9-10)14(4,5)6/h7-9,15H,1-6H;
    K743 KS-00000MO8 KSC490K4N
    LS-104318 MCULE-6010467095 MFCD00008828
    NCGC00164059-01 NCGC00164059-02 NCGC00164059-03
    NCGC00254167-01 NCGC00259869-01 NE10618
    NSC 174502 NSC-174502 NSC174502
    Phenol, 2,4-bis(1,1-dimethylethyl)- Phenol, 2,4-di(1,1-dimethylethyl)- Phenol, 2,4-di-tert-butyl-
    Phenol,2,4-Bis(1,1-dimethylethyl) Phenol,4-bis(1,1-dimethylethyl)- Phenol,4-di-tert-butyl-
    Prodox 146 Prodox 146A-85X PubChem16035
    Q-200191 Q26840829 RTR-031280
    SBB060741 SCHEMBL109921 ST2415739
    ST50308551 TR-031280 TRA-0206429
    Tox21_202320 Tox21_300114 UNII-FOB94G6HZT
    WLN: 1X1&1&R BQ CX1&1&1 ZINC1081075

    CAS Number 10523-68-9, 119345-01-6, 1246816-88-5, 141-91-3, 4180-12-5, 96-76-4
    PubChem Compound 7311
    ChEBI 89188