Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 3.50±0.73 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 3.98 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 24.04±16.59 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Danger |
Aggregated GHS information provided by 1607 companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 19 of 1607 companies. For more detailed information, please visit ECHA C&L website Of the 22 notification(s) provided by 1588 of 1607 companies with hazard statement code(s): H302 (54.97%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (92.07%): Causes skin irritation [Warning Skin corrosion/irritation] H318 (61.59%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H319 (30.48%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (20.59%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H400 (68.77%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (75.13%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Danger |
H315: Causes skin irritation [Warning Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P264, P273, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P362, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H315: Causes skin irritation [Warning Skin corrosion/irritation] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P260, P264, P270, P273, P280, P301+P312, P302+P352, P305+P351+P338, P309+P311, P314, P321, P330, P332+P313, P337+P313, P362, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H315: Causes skin irritation [Warning Skin corrosion/irritation] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P260, P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P309+P311, P314, P321, P330, P332+P313, P337+P313, P362, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
(2S)-N-[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-1-[[(1S)-4-amino-1-[(2S)-2-[(2-amino-2-oxo-ethyl)carbamoyl]pyrrolidine-1-carbonyl]-4-oxo-butyl]carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-1-(hydro | 1-Hydroxy-2,4-di-tert-butylbenzene | 2,4-Ditert-Butyl-Phenol |
2,4-Bis(1,1-dimethylethyl)phenol | 2,4-DI-T-BUTYLPHENOL | 2,4-DTBP |
2,4-Di-tert-butylhydroxybenzene | 2,4-Di-tert-butylphenol | 2,4-Di-tert-butylphenol, 97% |
2,4-Di-tert-butylphenol, 99% | 2,4-Di-tert.-butylphenol | 2,4-Di-tertbutyl-phenol |
2,4-bis(tert-butyl)phenol | 2,4-di-t-butyl-phenol | 2,4-di-tert-butyl phenol |
2,4-di-tert.butylphenol | 2,4-di-tertbutyl phenol | 2,4-di-tertbutylphenol |
2,4-ditert-butyl phenol | 2,4-ditert-butyl-phenol | 2,4-ditert-butylphenol |
2,4-ditertbutylphenol | 2,4-ditertiary-butyl phenol | 2,4-ditertiarybutylphenol |
2,4di-tert-butylphenol | 24-Ditert-Butyl-Phenol | 96-76-4 |
ACMC-209s7n | AKOS003669719 | ANW-40833 |
AS-13983 | Antioxidant No. 33 | BCP24012 |
BDBM50409544 | BRN 1910383 | CAS-96-76-4 |
CHEBI:89188 | CHEMBL29873 | CTK3J0546 |
D0229 | DSSTox_CID_6602 | DSSTox_GSID_26602 |
DSSTox_RID_78158 | DTXSID2026602 | EC 202-532-0 |
EINECS 202-532-0 | F0001-2302 | FOB94G6HZT |
FT-0610222 | ICKWICRCANNIBI-UHFFFAOYSA-N | InChI=1/C14H22O/c1-13(2,3)10-7-8-12(15)11(9-10)14(4,5)6/h7-9,15H,1-6H; |
K743 | KS-00000MO8 | KSC490K4N |
LS-104318 | MCULE-6010467095 | MFCD00008828 |
NCGC00164059-01 | NCGC00164059-02 | NCGC00164059-03 |
NCGC00254167-01 | NCGC00259869-01 | NE10618 |
NSC 174502 | NSC-174502 | NSC174502 |
Phenol, 2,4-bis(1,1-dimethylethyl)- | Phenol, 2,4-di(1,1-dimethylethyl)- | Phenol, 2,4-di-tert-butyl- |
Phenol,2,4-Bis(1,1-dimethylethyl) | Phenol,4-bis(1,1-dimethylethyl)- | Phenol,4-di-tert-butyl- |
Prodox 146 | Prodox 146A-85X | PubChem16035 |
Q-200191 | Q26840829 | RTR-031280 |
SBB060741 | SCHEMBL109921 | ST2415739 |
ST50308551 | TR-031280 | TRA-0206429 |
Tox21_202320 | Tox21_300114 | UNII-FOB94G6HZT |
WLN: 1X1&1&R BQ CX1&1&1 | ZINC1081075 |