Compound

D0651 | 2,5-di-tert-butylbenzene-1,4-diol

Molecular Formula C14H22O2
Molecular Weight 222.32
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 7.41±1.27 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 7.94 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 39.15±15.51 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Warning

Aggregated GHS information provided by 156 companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


Reported as not meeting GHS hazard criteria by 2 of 156 companies. For more detailed information, please visit ECHA C&L website


Of the 13 notification(s) provided by 154 of 156 companies with hazard statement code(s):


H302 (56.49%): Harmful if swallowed [Warning Acute toxicity, oral]


H315 (33.77%): Causes skin irritation [Warning Skin corrosion/irritation]


H317 (40.91%): May cause an allergic skin reaction [Warning Sensitization, Skin]


H319 (33.77%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335 (38.31%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 1, 2,5-bis(1,1-dimethylethyl)- 1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)- 1,4-Dihydroxy-2,5-di-tert-butylbenzene
    2,5-Bis(1,1-dimethylethyl)-1,4-benzenediol 2,5-DI-(TERT-BUTYL)-1,4,BENZOHYDROQUINONE 2,5-DITERT-BUTYLBENZENE-1,4-DIOL
    2,5-Di-(t-butyl)-1,4-hydroquinone 2,5-Di-t-butylhydroquinone 2,5-Di-tert-butyl-1,4-benzenediol
    2,5-Di-tert-butyl-1,4-benzohydroquinone 2,5-Di-tert-butyl-1,4-hydroquinone 2,5-Di-tert-butylbenzene-1,4-diol
    2,5-Di-tert-butylhydroquinone 2,5-Di-tert-butylhydroquinone, 99% 2,5-Di-tert-butylquinol
    2,5-Ditert-butyl-1,4-benzenediol # 2,5-TBHQ 2,5-bis(tert-butyl)benzene-1,4-diol
    2,5-di(tert-butyl)-1,4-benzohydroquinone 2,5-di-t-butyl hydroquinone 2,5-di-t-butylquinol
    2,5-di-tert--butyl-hydroquinone 2,5-di-tert--butylbenzene-1,4-diol 2,5-di-tert-butyl-1,4-dihydroxybenzene
    2,5-di-tert-butyl-hydroquinone 2,5-di-tertbutylhydroquinone 2,5-ditert-butyl hydroquinone
    26XK13B61B 2agv 88-58-4
    AC-2488 ACMC-209qun AI3-16630
    AK-44131 AKOS003627062 ANW-39069
    Antage DBH B6648 BDBM176764
    BR-44131 BRD-K95603879-001-03-4 BRD-K95603879-001-06-7
    BRN 2049542 BSPBio_001029 Bio1_000419
    Bio1_000908 Bio1_001397 Bio2_000345
    Bio2_000825 CAS# 88-58-4 CAS-88-58-4
    CBDivE_001992 CCRIS 5218 CHEBI:41094
    CHEMBL480626 CTK3J0584 Cambridge id 5105618
    D0940 DB-057086 DB04638
    DSSTox_CID_21248 DSSTox_GSID_41248 DSSTox_RID_79662
    DTBHQ DTXSID8041248 Di-t-butylhydroquinone
    Dibug Dybug EINECS 201-841-8
    Eastman DTBHQ FT-0610494 HMS1362C11
    HMS1792C11 HMS1990C11 HMS3267F19
    HMS3403C11 HMS3412A14 HMS3676A14
    HSCI1_000289 HYDROQUINONE, 2,5-DI-tert-BUTYL- Hydroquinone,5-di-tert-butyl-
    Hydrpquinone, 2,5-di-tert-butyl- IDI1_002100 InChI=1/C14H22O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8,15-16H,1-6H;
    JZODKRWQWUWGCD-UHFFFAOYSA-N KBio2_000369 KBio2_002937
    KBio2_005505 KBio3_000717 KBio3_000718
    KBioGR_000369 KBioSS_000369 KS-0000012Y
    KSC490K8J LS-77292 M-5878
    MCULE-4467634712 MFCD00008825 MLS001066345
    NCGC00025066-01 NCGC00025066-02 NCGC00025066-03
    NCGC00025066-04 NCGC00254338-01 NSC 11
    NSC-11 NSC-9886 NSC11
    NSC9886 Naugard 451 Nocrac NS 7
    Nonflex Alba Oprea1_534698 PS-7822
    PubChem14586 Q-200201 Q27095374
    RTR-027845 SCHEMBL38604 SMR000135117
    SR-01000597417 SR-01000597417-1 ST2409136
    ST50308012 Santovar O TR-027845
    TRA0067998 Tocris-1236 Tox21_300385
    U029 UNII-26XK13B61B US9688816, 7
    WLN: L6V DVJ BX1&1&1 EX1&1&1 Z1741982433 ZINC56404
    bhq di-tert-butylhydroquinone s3628
    t-BuBHQ tBuBHQ

    CAS Number 88-58-4, 94386-29-5
    PubChem Compound 2374
    ChEBI 41094