Compound

D0660 | 2-amino-4-chloro-5-nitrophenol

Molecular Formula C6H5ClN2O3
Molecular Weight 188.57
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 21.51±2.48 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 25.12 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 31.27±8.72 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Warning

Aggregated GHS information provided by 73 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


Reported as not meeting GHS hazard criteria by 1 of 73 companies. For more detailed information, please visit ECHA C&L website


Of the 3 notification(s) provided by 72 of 73 companies with hazard statement code(s):


H302 (98.61%): Harmful if swallowed [Warning Acute toxicity, oral]


H312 (98.61%): Harmful in contact with skin [Warning Acute toxicity, dermal]


H315 (54.17%): Causes skin irritation [Warning Skin corrosion/irritation]


H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H332 (98.61%): Harmful if inhaled [Warning Acute toxicity, inhalation]


H335 (98.61%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


H411 (45.83%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 2-13-00-00196 (Beilstein Handbook Reference) 2-Amino-4-chloro-5-nitrophenol 2-Amino-4-chloro-5-nitrophenol, 98%
    2-Naphthalenecarboxamide,N-(2,3-dimethylphenyl)-3-hydroxy- 2-amino-4-chloro-5-nitro-phenol 2-amino4-chloro-5-nitrophenol
    2-azanyl-4-chloranyl-5-nitro-phenol 5-Chloro-2-hydroxy-4-nitroaniline 6358-02-7
    6358-07-2 A1228 A834422
    AC-8703 ACMC-1B2SV AKOS000120072
    ANW-14044 AS-11969 BRN 3268343
    CAS-6358-07-2 CCRIS 4577 CHEMBL1588831
    CTK5B9498 DB-015257 DSSTox_CID_4471
    DSSTox_GSID_24471 DSSTox_RID_77414 DTXSID5024471
    EINECS 228-760-0 FT-0618123 FT-0636112
    InChI=1/C6H5ClN2O3/c7-3-1-4(8)6(10)2-5(3)9(11)12/h1-2,10H,8H; KS-000002HJ KS-00000YM4
    LS-1528 LS10705 MCULE-7495798993
    NCGC00091280-01 NCGC00091280-02 NCGC00257627-01
    NE10682 NSC 7537 NSC-7537
    NSC7537 Phenol, 2-amino-4-chloro-5-nitro- Phenol,2-amino-4-chloro-5-nitro-
    PubChem1477 SCHEMBL303378 ST2416382
    ST50973623 TC-102789 Tox21_200073
    VZ23615 W-104901 ZARYBZGMUVAJMK-UHFFFAOYSA-N
    ZINC4411144 amino-4-chloro-5-nitrophenol

    CAS Number 6358-02-7, 6358-07-2
    PubChem Compound 3894848