MITOTOX

Compound

D0671 | 2-hydrazino-4-phenylthiazole

Properties

Molecular Formula	C9H9N3S
Molecular Weight	191.26
Structure

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Species	Model	Method	Action	Positive criterion	Reference
MEMBRANE POTENTIAL	2.32±0.79	human	qHTS-HepG2	MMP assay	decrease	IC50	163
MEMBRANE POTENTIAL	10	human	HepG2	MMP assay	decrease	IC50	163
MEMBRANE POTENTIAL	21.46±17.61	rat	hepatocytes	MMP assay	decrease	IC50	163

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Danger	Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P264, P270, P280, P301+P310, P305+P351+P338, P310, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Danger

Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P264, P270, P280, P301+P310, P305+P351+P338, P310, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Indications Source: SIDER

Synonyms Source: PubChem

(4-Phenyl-thiazol-2-yl)-hydrazine	(4-Phenylthiazol-2-yl)hydrazine	(4-phenyl-1,3-thiazol-2-yl)hydrazine
(4-phenyl-2-thiazolyl)hydrazine	1-(4-Phenyl-2-thiazolyl)hydrazine	2(3H)-Thiazolone, 4-phenyl-, hydrazone
2(3H)-Thiazolone, 4-phenyl-, hydrazone (9CI)	2-Hydrazino-4-phenyl-1,3-thiazole	2-Hydrazino-4-phenyl-1,3-thiazole #
2-Hydrazino-4-phenylthiazole	2-Hydrazino-4-phenylthiazole, 97%	2-Hydrazinyl-4-phenylthiazole
2-hydrazino-4-phenyl-1,3-thiazole hydrochloride	2-hydrazinyl-4-phenyl-1,3-thiazole	34176-52-8
4-Phenylthiazolone-(2)-hydrazone	4-phenyl-1,3-thiazole-2-ylhydrazine	8802AH
AKOS000294577	AS-47268	BB 0217833
BBL038136	CAS-34176-52-8	CBMicro_024563
CHEBI:103947	CHEMBL82154	CTK4H1863
DSSTox_CID_707	DSSTox_GSID_20707	DSSTox_RID_75748
DTXSID8020707	FT-0709722	J-019480
LS-7435	MCULE-5361613079	NCGC00246115-01
NCGC00246115-02	NCGC00258451-01	NE36519
NSC 153290	NSC-153290	NSC153290
Oprea1_007602	Q27181172;	SBB017484
SCHEMBL1302488	ST078483	STK299448
Thiazole,2-hydrazinyl-4-phenyl-	Thiazole-2-hydrazine, 4-phenyl-	Tox21_200897
UNII-V93UR7ZO5R	V93UR7ZO5R	VTOUNUQLXMNNMQ-UHFFFAOYSA-N
ZINC18101453

External IDs

CAS Number	17574-10-6, 34176-52-8
PubChem Compound	98613