Compound
D0687 | 2-tert-butyl-4-methoxyphenol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 25.29±1.71 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 35.48 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 36.50±19.25 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
  |
Warning |
H303: May be harmful if swallowed [Warning Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure Narcotic effects] H351: Suspected of causing cancer [Warning Carcinogenicity] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] |
P201, P202, P261, P271, P272, P280, P281, P302+P352, P304+P340, P308+P313, P312, P321, P333+P313, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 29mg/kg (29mg/kg) | gastrointestinal: other changes | Pharmacological Research Communications. Vol. 16, Pg. 1041, 1984. |
| rat | LD50 | oral | 2910mg/kg (2910mg/kg) | gastrointestinal: other changes | Pharmacological Research Communications. Vol. 16, Pg. 1041, 1984. |
| mouse | LD50 | oral | 1583mg/kg (1583mg/kg) | gastrointestinal: other changes | Pharmacological Research Communications. Vol. 16, Pg. 1041, 1984. |
| rat | LD50 | intraperitoneal | 32mg/kg (32mg/kg) | gastrointestinal: other changes | Pharmacological Research Communications. Vol. 16, Pg. 1041, 1984. |
| 121-00-6 | 2(3)-t-Butyl-4-hydroxyanisole | 2(3)-tert-Butyl-4-hydroxyanisole |
| 2-(1,1-Dimethylethyl)-4-methoxy-phenol | 2-(1,1-dimethylethyl)-4-methoxyphenol | 2-(tert-butyl)-4-methoxyphenol |
| 2-Butyl-4-hydroxyanisole | 2-t-butyl-4-methoxyphenol | 2-tert-Bha |
| 2-tert-Butyl-4-methoxy-phenol | 2-tert-Butyl-4-methoxyphenol | 2-tert-Butyl-4-methoxyphenol 100 microg/mL in Ethanol |
| 25013-16-5 | 3-(1,1-Dimethylethyl)-4-hydroxyanisole | 3-BHA |
| 3-T-BUTYL-4-HYDROXYANISOLE | 3-tert-Butyl-4-hydroxyani | 3-tert-Butyl-4-hydroxyanisole |
| 3-tert-Butyl-4-hydroxyanisole, 98% | 3-tert-Butyl-4-hydroxyanisole, >=98% (sum of isomers, GC), <=10% 2-BHA basis (GC) | 3-tert-Butyl-4-hydroxyanisole, Pharmaceutical Secondary Standard |
| 3-tert-Butyl-4-hydroxyanisole, United States Pharmacopeia (USP) Reference Standard | 3-tert-Butyl-4-hydroxyanisole, tested according to Ph.Eur. | 3-tert-Butyl-p-hydroxyanisole |
| 3-tert-butyl-4-hydroxyanisol | 3670AA | 4-Hydroxy-3-tert-butylanisole |
| 4-Methoxy-2-tert-butylphenol | 4-Methoxy-6-tert-butylphenol | 62RAC24292 |
| 921-00-6; | AB00514297_09 | ACMC-209a8y |
| AKOS000120777 | ALBB-023610 | ANW-17552 |
| AS-63590 | B0723 | BBL027948 |
| BENZENE,1-TERT.BUTYL,2-HYDROXY,5-METHOXY | BIDD:ER0078 | BRN 1867499 |
| Bha-33 | Butylated hydroxyanisole I (D) | Butylated hydroxyanisole, 96% |
| CAS-121-00-6 | CAS-25013-16-5 | CB-1801 |
| CCG-107062 | CCRIS 3746 | CHEBI:76358 |
| CHEMBL192451 | CTK3J0489 | Certified Reference Material |
| DSSTox_CID_215 | DSSTox_GSID_20215 | DSSTox_GSID_40788 |
| DSSTox_RID_75439 | DSSTox_RID_79600 | DTXSID7040788 |
| EINECS 204-442-7 | EU-0072133 | FT-0616393 |
| FT-0689268 | HMS1610G14 | HMS2233F16 |
| HMS3370C01 | HSDB 2750 | InChI=1/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H |
| LS-104168 | M136 | MCULE-8962607460 |
| MFCD01779059 | MLS000069623 | MRBKEAMVRSLQPH-UHFFFAOYSA-N |
| NCGC00159405-02 | NCGC00159405-03 | NCGC00159405-04 |
| NCGC00159405-05 | NCGC00254068-01 | NCGC00259371-01 |
| Phenol, (1,1-dimethylethyl)-4-methoxy- | Phenol, 2-(1,1-dimethylethyl)-4-methoxy- | Phenol, 2-tert-butyl-4-methoxy- |
| Phenol,2-(1,1-dimethylethyl)-4-methoxy- | Q-200395 | Q27145913 |
| R1687 | SBB043781 | SCHEMBL35535 |
| SMR000058171 | ST24039776 | ST45022092 |
| STL377914 | TC-106297 | TRA0163777 |
| Tertiary butyl hydroxyanisole (Related) | Tox21_201822 | Tox21_300082 |
| UNII-62RAC24292 | UNII-REK4960K2U component MRBKEAMVRSLQPH-UHFFFAOYSA-N | ZINC1080 |
| butylhydroxyanisol | o-tert-Butyl-p-methoxyphenol | p-methoxy-o-tert-butylphenol |