Compound
D0700 | 3-amino-9-ethylcarbazole hydrochloride
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 35.36±24.49 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 14.13 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 56.23±0.00 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Danger |
Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P301+P310, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | oral | 234mg/kg (234mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 450, 1950. | |
| 12C4938KM9 | 3-AMINO-9-ETHYL CARBAZOLE HYDROCHLORIDE | 3-Amino-9-ethylcarbazole HCl |
| 3-Amino-9-ethylcarbazole hydrochloride | 3-Amino-9-ethylcarbazole hydrochloride (1:1) | 3-Amino-9-ethylcarbazole monohydrochloride |
| 3-Amino-9-ethylcarbazole.HCl | 3-Amino-9-ethylcarbozole hydrochloride | 3-amino-9-eth-ylcarbazole hydrochloride |
| 57360-17-5 | 6109-97-3 | 9-ethyl-9H-carbazol-3-amine hydrochloride |
| 9-ethylcarbazol-3-amine hydrochloride | 9H-Carbazol-3-amine, 9-ethyl-, hydrochloride | 9H-Carbazol-3-amine, 9-ethyl-, monohydrochloride (1:1) |
| AKOS008056530 | CAS-6109-97-3 | CCRIS 5885 |
| CHEMBL3182857 | CTK1H0849 | Carbazole, 3-amino-9-ethyl-, hydrochloride |
| Carbazole, hydrochloride | DSSTox_CID_54 | DSSTox_GSID_20054 |
| DSSTox_RID_75338 | DTXSID2020054 | EINECS 228-072-0 |
| LS-1459 | MCULE-5752964360 | NCGC00258040-01 |
| NCI-C03043 | NSC 7426 | NSC-7426 |
| NSC7426 | Q27251403; | Tox21_200486 |
| UNII-12C4938KM9 | WLN: T B656 HNJ DZ H2 &GH |
| CAS Number | 57360-17-5, 6109-97-3 |
| PubChem Compound | 62130 |